BR9708980A - Aperfeiçoamento das taxas de implantação após fertilização invitro - Google Patents
Aperfeiçoamento das taxas de implantação após fertilização invitroInfo
- Publication number
- BR9708980A BR9708980A BR9708980A BR9708980A BR9708980A BR 9708980 A BR9708980 A BR 9708980A BR 9708980 A BR9708980 A BR 9708980A BR 9708980 A BR9708980 A BR 9708980A BR 9708980 A BR9708980 A BR 9708980A
- Authority
- BR
- Brazil
- Prior art keywords
- invitro
- fertilization
- improvement
- implantation rates
- implantation
- Prior art date
Links
- 230000004720 fertilization Effects 0.000 title 1
- 238000002513 implantation Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/223—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of alpha-aminoacids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/34—Gestagens
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Diabetes (AREA)
- Pregnancy & Childbirth (AREA)
- Emergency Medicine (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/646,518 US6040340A (en) | 1996-05-07 | 1996-05-07 | Implantation rates after in vitro fertilization, treatment of infertility and early pregnancy loss with a nitric oxide donor alone or in combination with progesterone, and a method for contraception with nitric oxide inhibitors |
PCT/EP1997/002371 WO1997041866A1 (en) | 1996-05-07 | 1997-05-07 | Improvement of implantation rates after in vitro fertilization |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9708980A true BR9708980A (pt) | 1999-08-03 |
Family
ID=24593350
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9708980A BR9708980A (pt) | 1996-05-07 | 1997-05-07 | Aperfeiçoamento das taxas de implantação após fertilização invitro |
Country Status (17)
Country | Link |
---|---|
US (1) | US6040340A (pt) |
EP (1) | EP0906105A1 (pt) |
JP (1) | JP2000510462A (pt) |
KR (1) | KR20040097370A (pt) |
CN (2) | CN1315478C (pt) |
AP (1) | AP9801384A0 (pt) |
BG (1) | BG62953B1 (pt) |
BR (1) | BR9708980A (pt) |
CA (1) | CA2253751A1 (pt) |
EA (1) | EA199800986A1 (pt) |
EE (1) | EE9800387A (pt) |
IL (1) | IL126755A0 (pt) |
IS (1) | IS4882A (pt) |
NO (1) | NO985204L (pt) |
PL (1) | PL329766A1 (pt) |
TR (1) | TR199802254T2 (pt) |
WO (1) | WO1997041866A1 (pt) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2367002A1 (en) * | 1999-03-19 | 2000-09-28 | Michael A. Moskowitz | Increasing cerebral bioavailability of drugs |
US7629334B1 (en) * | 1999-08-31 | 2009-12-08 | Bayer Schering Pharma Aktiengesellschaft | Mesoprogrestins (progesterone receptor modulations) as a component of compositions for hormone replacement therapy (HRT) |
CO5190694A1 (es) * | 1999-08-31 | 2002-08-29 | Jenapharm Gmbh And Co Kg | Mesoprogestinas (moduladores de receptores de progesterona) como componentes de anticonceptivos femeninos |
AU1951701A (en) | 1999-12-10 | 2001-06-18 | Board Of Trustees Of The Leland Stanford Junior University | Methods for modulation of oocyte activation |
ITMI20002117A1 (it) * | 2000-09-29 | 2002-03-29 | Ibsa Inst Biochimique Sa | Uso di sodio nitroprussiato in ostetricia e ginecologia |
US7179798B2 (en) * | 2001-11-16 | 2007-02-20 | Russell R. Roby | Methods and compositions for the treatment of pain and other hormone-allergy-related symptoms using dilute hormone solutions |
WO2003099333A1 (en) * | 2002-05-23 | 2003-12-04 | Reproductive Health Technologies, Inc. | Methods of controlling fertility, cancers and reproductive tract diseases |
FR2842108B1 (fr) | 2002-07-09 | 2008-05-02 | Effik | Composes a base d'hormone et de monoxyde d'azote et leur utilisation en obstetrique et en gynecologie |
MXPA05004290A (es) * | 2002-10-24 | 2005-11-23 | Enos Pharmaceuticals Inc | Formulaciones de l-arginina de liberacion sostenida, y metodos para su fabricacion y uso. |
US20080145424A1 (en) * | 2002-10-24 | 2008-06-19 | Enos Phramaceuticals, Inc. | Sustained release L-arginine formulations and methods of manufacture and use |
US20050065136A1 (en) * | 2003-08-13 | 2005-03-24 | Roby Russell R. | Methods and compositions for the treatment of infertility using dilute hormone solutions |
JP2007521324A (ja) * | 2003-09-29 | 2007-08-02 | エノス ファーマシューティカルズ, インク. | 徐放性l−アルギニン調合物並びにその製造法及び使用法 |
US20090226397A1 (en) | 2003-10-24 | 2009-09-10 | Nora Therapeutics, Inc. | Compositions and methods for reducing the likelihood of implantation failure or miscarriage in recipients of artificial insemination |
DK2213295T3 (da) * | 2003-10-24 | 2013-05-06 | Nora Therapeutics Inc | Fremgangsmåde til opnåelse af data, som er nyttige til identifikation af en patient, som er udsat for risiko for at have vanskeligheder ved at opretholde en graviditet |
US8338373B2 (en) * | 2003-10-24 | 2012-12-25 | Nora Therapeutics, Inc. | Method for reducing the risk of spontaneous abortion in a human female subject |
EP1550447A1 (en) * | 2004-01-02 | 2005-07-06 | Schering Aktiengesellschaft | Menstrual cycle control and improvement of conception rates in females |
US20050239757A1 (en) * | 2004-04-21 | 2005-10-27 | Roby Russell R | Hormone treatment of macular degeneration |
US20050239758A1 (en) * | 2004-04-21 | 2005-10-27 | Roby Russell R | Hormone treatment of multiple sclerosis |
CA3009909A1 (en) | 2004-05-17 | 2005-12-22 | The General Hospital Corporation | Compositions comprising female germline stem cells and methods of use thereof |
US20060025390A1 (en) * | 2004-07-28 | 2006-02-02 | Roby Russell R | Treatment of hormone allergy and related symptoms and disorders |
US8828981B2 (en) * | 2007-02-06 | 2014-09-09 | George Creasy | Progesterone for the treatment or prevention of spontaneous preterm birth |
WO2012142500A2 (en) | 2011-04-14 | 2012-10-18 | The General Hospital Corporation | Compositions and methods for autologous germline mitochondrial energy transfer |
EP3495470A1 (en) | 2011-06-29 | 2019-06-12 | The General Hospital Corporation | In vivo methods for enhancing bioenergetic status in female germ cells |
US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
RS62297B1 (sr) | 2011-11-23 | 2021-09-30 | Therapeuticsmd Inc | Prirodne kombinovane hormonske supstitucione formulacije i terapije |
US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
JP2017516768A (ja) | 2014-05-22 | 2017-06-22 | セラピューティックスエムディー インコーポレーテッドTherapeuticsmd, Inc. | 天然の併用ホルモン補充療法剤及び療法 |
US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
RU2018133932A (ru) | 2016-04-01 | 2020-05-12 | Терапьютиксмд, Инк. | Фармацевтическая композиция стероидного гормона |
WO2017173044A1 (en) | 2016-04-01 | 2017-10-05 | Therapeuticsmd Inc. | Steroid hormone compositions in medium chain oils |
US11633405B2 (en) | 2020-02-07 | 2023-04-25 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical formulations |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5508045A (en) * | 1992-10-09 | 1996-04-16 | The Regents Of The University Of California | Method and agents for control and management of labor during pregnancy |
US5595970A (en) * | 1993-07-16 | 1997-01-21 | Schering Aktiengesellschaft | Treatment of climacteric disorders with nitric oxide synthase substrates and/or donors |
US5470847A (en) * | 1993-12-10 | 1995-11-28 | Board Of Regents, The University Of Texas System | Ovulation control by regulating nitric oxide levels with arginine derivatives |
-
1996
- 1996-05-07 US US08/646,518 patent/US6040340A/en not_active Expired - Fee Related
-
1997
- 1997-05-07 WO PCT/EP1997/002371 patent/WO1997041866A1/en active IP Right Grant
- 1997-05-07 IL IL12675597A patent/IL126755A0/xx not_active IP Right Cessation
- 1997-05-07 PL PL97329766A patent/PL329766A1/xx unknown
- 1997-05-07 AP APAP/P/1998/001384A patent/AP9801384A0/en unknown
- 1997-05-07 EE EE9800387A patent/EE9800387A/xx unknown
- 1997-05-07 JP JP09539553A patent/JP2000510462A/ja not_active Ceased
- 1997-05-07 TR TR1998/02254T patent/TR199802254T2/xx unknown
- 1997-05-07 CN CNB971944520A patent/CN1315478C/zh not_active Expired - Fee Related
- 1997-05-07 CN CNA2005100038226A patent/CN1679939A/zh active Pending
- 1997-05-07 EP EP97923032A patent/EP0906105A1/en not_active Withdrawn
- 1997-05-07 CA CA002253751A patent/CA2253751A1/en not_active Abandoned
- 1997-05-07 KR KR10-2004-7016777A patent/KR20040097370A/ko active IP Right Grant
- 1997-05-07 EA EA199800986A patent/EA199800986A1/ru unknown
- 1997-05-07 BR BR9708980A patent/BR9708980A/pt not_active Application Discontinuation
-
1998
- 1998-10-29 IS IS4882A patent/IS4882A/is unknown
- 1998-10-29 BG BG102881A patent/BG62953B1/bg unknown
- 1998-11-06 NO NO985204A patent/NO985204L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA2253751A1 (en) | 1997-11-13 |
TR199802254T2 (xx) | 1999-03-22 |
EE9800387A (et) | 1999-04-15 |
IS4882A (is) | 1998-10-29 |
NO985204L (no) | 1999-01-06 |
EA199800986A1 (ru) | 1999-04-29 |
CN1218402A (zh) | 1999-06-02 |
US6040340A (en) | 2000-03-21 |
CN1315478C (zh) | 2007-05-16 |
BG62953B1 (bg) | 2000-12-29 |
AP9801384A0 (en) | 1998-12-31 |
KR20040097370A (ko) | 2004-11-17 |
JP2000510462A (ja) | 2000-08-15 |
NO985204D0 (no) | 1998-11-06 |
WO1997041866A1 (en) | 1997-11-13 |
PL329766A1 (en) | 1999-04-12 |
CN1679939A (zh) | 2005-10-12 |
BG102881A (en) | 1999-06-30 |
IL126755A0 (en) | 1999-08-17 |
EP0906105A1 (en) | 1999-04-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |