BR9708369A - Process for the preparation of n-methyl-d-phenyl alanyl-n- [1- [3. (amino imino methyl) amino [propyl] -3,3-difluoro-2-oxo hexyl] -L-prolinamide - Google Patents

Process for the preparation of n-methyl-d-phenyl alanyl-n- [1- [3. (amino imino methyl) amino [propyl] -3,3-difluoro-2-oxo hexyl] -L-prolinamide

Info

Publication number
BR9708369A
BR9708369A BR9708369A BR9708369A BR9708369A BR 9708369 A BR9708369 A BR 9708369A BR 9708369 A BR9708369 A BR 9708369A BR 9708369 A BR9708369 A BR 9708369A BR 9708369 A BR9708369 A BR 9708369A
Authority
BR
Brazil
Prior art keywords
amino
methyl
prolinamide
difluoro
propyl
Prior art date
Application number
BR9708369A
Other languages
Portuguese (pt)
Inventor
Duane Eric Rudisill
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of BR9708369A publication Critical patent/BR9708369A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C277/00—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C277/08—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups of substituted guanidines
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BR9708369A 1996-03-26 1997-02-25 Process for the preparation of n-methyl-d-phenyl alanyl-n- [1- [3. (amino imino methyl) amino [propyl] -3,3-difluoro-2-oxo hexyl] -L-prolinamide BR9708369A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62472196A 1996-03-26 1996-03-26
PCT/US1997/002869 WO1997035874A1 (en) 1996-03-26 1997-02-25 Process for the preparation of n-methyl-d-phenylalanyl-n-[1-[3-[(aminoiminomethyl)amino]propyl]-3,3-difluoro-2-oxohexyl]-l-prolinamide

Publications (1)

Publication Number Publication Date
BR9708369A true BR9708369A (en) 1999-08-03

Family

ID=24503070

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9708369A BR9708369A (en) 1996-03-26 1997-02-25 Process for the preparation of n-methyl-d-phenyl alanyl-n- [1- [3. (amino imino methyl) amino [propyl] -3,3-difluoro-2-oxo hexyl] -L-prolinamide

Country Status (13)

Country Link
EP (1) EP1012165A1 (en)
JP (1) JP2000507267A (en)
KR (1) KR20000004991A (en)
CN (1) CN1121410C (en)
AR (1) AR006366A1 (en)
AU (1) AU710040B2 (en)
BR (1) BR9708369A (en)
CA (1) CA2250583C (en)
IL (1) IL126071A (en)
NO (1) NO984490D0 (en)
NZ (1) NZ331432A (en)
WO (1) WO1997035874A1 (en)
ZA (1) ZA972506B (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0503203A1 (en) * 1991-03-15 1992-09-16 Merrell Dow Pharmaceuticals Inc. Novel thrombin inhibitors

Also Published As

Publication number Publication date
AU710040B2 (en) 1999-09-09
CN1121410C (en) 2003-09-17
EP1012165A1 (en) 2000-06-28
WO1997035874A1 (en) 1997-10-02
NO984490L (en) 1998-09-25
KR20000004991A (en) 2000-01-25
CN1214691A (en) 1999-04-21
AU2055097A (en) 1997-10-17
JP2000507267A (en) 2000-06-13
ZA972506B (en) 1997-09-26
AR006366A1 (en) 1999-08-25
IL126071A (en) 2003-06-24
NO984490D0 (en) 1998-09-25
NZ331432A (en) 2000-03-27
CA2250583C (en) 2003-01-14
CA2250583A1 (en) 1997-10-02
IL126071A0 (en) 1999-05-09

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]