BR9608482A - Genes receptores de transferrina - Google Patents

Genes receptores de transferrina

Info

Publication number
BR9608482A
BR9608482A BR9608482-0A BR9608482A BR9608482A BR 9608482 A BR9608482 A BR 9608482A BR 9608482 A BR9608482 A BR 9608482A BR 9608482 A BR9608482 A BR 9608482A
Authority
BR
Brazil
Prior art keywords
transferrin receptor
nucleic acid
receptor protein
tbp1
receptor genes
Prior art date
Application number
BR9608482-0A
Other languages
English (en)
Inventor
Sheena M Loosmore
Robin E Harkness
Anthony B Schryvers
Pele Chong
Scott Gray-Owen
Yan-Pin Yang
Michel H Klein
Andrew D Murdin
Original Assignee
Connaught Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/483,577 external-priority patent/US6015688A/en
Application filed by Connaught Lab filed Critical Connaught Lab
Publication of BR9608482A publication Critical patent/BR9608482A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/285—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

<B>GENES RECEPTORES DE TRANSFERRINA<D> é proporcionado um ácido nucléico purificado e isolado que codifica uma proteína receptora de transferrina de uma cepa de Haemophilus, ou um fragmento ou um análogo da proteína receptora de transferrina. A seq³ência de ácido nucléico pode ser usada para produzir pepetídeos isentos de contaminantes derivados de bactéria contendo normalmente as proteínas Tbp1 ou Tbp2 para fins de diagnóstico e tratamento médico. Além disso, a molécula de ácido nucléico pode ser usada no diagnóstico de infecção. São também proporcionados Tbp1 e Tbp2 e métodos para purificação das mesmas. Vetores vivos expressando epitopos de proteína receptora de transferrina para vacinação também são proporcionados.
BR9608482-0A 1995-06-07 1996-06-07 Genes receptores de transferrina BR9608482A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/483,577 US6015688A (en) 1993-11-08 1995-06-07 Transferrin receptor genes
US08/649,518 US6361779B1 (en) 1993-11-08 1996-05-17 Transferrin receptor genes
PCT/CA1996/000399 WO1996040929A2 (en) 1995-06-07 1996-06-07 Transferrin receptor genes

Publications (1)

Publication Number Publication Date
BR9608482A true BR9608482A (pt) 2001-07-31

Family

ID=27047700

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9608482-0A BR9608482A (pt) 1995-06-07 1996-06-07 Genes receptores de transferrina

Country Status (8)

Country Link
US (2) US6361779B1 (pt)
EP (1) EP0833920B1 (pt)
AT (1) ATE274059T1 (pt)
AU (1) AU716506B2 (pt)
BR (1) BR9608482A (pt)
CA (1) CA2223503C (pt)
DE (1) DE69633179T2 (pt)
WO (1) WO1996040929A2 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7785609B1 (en) 1999-03-16 2010-08-31 Sanofi Pasteur Limited Recombinant Haemophilus influenzae adhesin proteins
US6335182B1 (en) * 1999-03-16 2002-01-01 Aventis Pasteur Limited Recombinant Haemophilus influenzae adhesin proteins
WO2004015099A2 (en) 2002-08-02 2004-02-19 Glaxosmithkline Biologicals Sa Vaccine composition comprising lipooligosaccharide with reduced phase variability
JP2013521770A (ja) 2010-03-10 2013-06-13 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム ワクチン組成物
PT2646470T (pt) 2010-11-30 2017-05-03 Hoffmann La Roche Anticorpos anti-recetor da transferrina de baixa afinidade e a sua utilização na transferência de scfv terapêuticos através da barreira hematoencefálica
BR112015030892A2 (pt) 2013-06-10 2017-08-29 Merck Sharp & Dohme Proteína de ligação ao antígeno, anticorpo monoclonal, ácido nucleico recombinante, vetor de expressão, célula hospedeira, composição farmacêutica, uso de uma proteína de ligação ao antígeno ou anticorpo humanizado, e, método para produzir uma proteína de ligação ao antígeno
JP2016539950A (ja) 2013-12-02 2016-12-22 ビー． シュライバーズ，アンソニー 細菌表面受容体タンパク質由来の免疫原性組成物およびワクチン

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4258029A (en) 1979-04-23 1981-03-24 Connaught Laboratories Limited Synthetic adjuvants for stimulation of antigenic responses
US4596792A (en) 1981-09-04 1986-06-24 The Regents Of The University Of California Safe vaccine for hepatitis containing polymerized serum albumin
US4496538A (en) 1982-07-06 1985-01-29 Connaught Laboratories, Inc. Haemophilus influenzae b polysaccharide-diphtheria toxoid conjugate vaccine
US4599230A (en) 1984-03-09 1986-07-08 Scripps Clinic And Research Foundation Synthetic hepatitis B virus vaccine including both T cell and B cell determinants
US4599231A (en) 1984-03-09 1986-07-08 Scripps Clinic And Research Foundation Synthetic hepatitis B virus vaccine including both T cell and B cell determinants
US4952496A (en) 1984-03-30 1990-08-28 Associated Universities, Inc. Cloning and expression of the gene for bacteriophage T7 RNA polymerase
US4601903A (en) 1985-05-01 1986-07-22 The United States Of America As Represented By The Department Of Health And Human Services Vaccine against Neisseria meningitidis Group B serotype 2 invasive disease
DE3521994A1 (de) 1985-06-20 1987-01-02 Bayer Ag N-(2-aminoacylamido-2-desoxy-hexosyl)-amide-, -carbamate und -harnstoffe, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
US5194254A (en) 1986-05-06 1993-03-16 Connaught Laboratories Limited Enhancement of antigen immunogenicity
US5141743A (en) 1989-04-27 1992-08-25 University Technologies International, Inc. Method for isolating and purifying transferrin and lactoferrin receptor proteins and vaccines containing the same
ES2108111T3 (es) 1991-04-02 1997-12-16 Biotech Australia Pty Ltd Sistemas de suministro oral de microparticulas.
GB9224584D0 (en) 1992-11-23 1993-01-13 Connaught Lab Use of outer membrane protein d15 and its peptides as vaccine against haempohilus influenzae diseases
AU705998B2 (en) 1993-11-08 1999-06-03 Connaught Laboratories Limited Haemophilus transferrin receptor genes

Also Published As

Publication number Publication date
EP0833920A2 (en) 1998-04-08
DE69633179D1 (de) 2004-09-23
DE69633179T2 (de) 2005-08-18
US20030088086A1 (en) 2003-05-08
JPH11506335A (ja) 1999-06-08
JP3516688B2 (ja) 2004-04-05
AU716506B2 (en) 2000-02-24
CA2223503A1 (en) 1996-12-19
US7118749B2 (en) 2006-10-10
WO1996040929A2 (en) 1996-12-19
ATE274059T1 (de) 2004-09-15
WO1996040929A3 (en) 1997-03-06
EP0833920B1 (en) 2004-08-18
AU6117796A (en) 1996-12-30
CA2223503C (en) 2010-05-04
US6361779B1 (en) 2002-03-26

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Legal Events

Date Code Title Description
EG Technical examination (opinion): publication of technical examination (opinion)
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: DE ACORDO COM O ART. 36 DA LPI (LEI 9279/96) 2O, O PEDIDO VOLTA A EXAME SENDO CONSIDERADO NAO PATENTEAVEL PELAS RAZOES EXPOSTAS NO PARECER TECNICO ANTERIOR.