BR9403572A - Composto, processo para sua preparação e formulação farmacêutica - Google Patents
Composto, processo para sua preparação e formulação farmacêuticaInfo
- Publication number
- BR9403572A BR9403572A BR9403572A BR9403572A BR9403572A BR 9403572 A BR9403572 A BR 9403572A BR 9403572 A BR9403572 A BR 9403572A BR 9403572 A BR9403572 A BR 9403572A BR 9403572 A BR9403572 A BR 9403572A
- Authority
- BR
- Brazil
- Prior art keywords
- preparation
- compound
- pharmaceutical formulation
- difluororibosyl
- deoxynucleosides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
- C07H5/06—Aminosugars
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Quinoline Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Noodles (AREA)
- Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/122,876 US5480992A (en) | 1993-09-16 | 1993-09-16 | Anomeric fluororibosyl amines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9403572A true BR9403572A (pt) | 1995-05-16 |
Family
ID=22405359
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9403572A BR9403572A (pt) | 1993-09-16 | 1994-09-15 | Composto, processo para sua preparação e formulação farmacêutica |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US5480992A (pt) |
| EP (1) | EP0647654B1 (pt) |
| JP (1) | JP3762445B2 (pt) |
| KR (1) | KR100322355B1 (pt) |
| AT (1) | ATE186731T1 (pt) |
| BR (1) | BR9403572A (pt) |
| CA (1) | CA2130124C (pt) |
| DE (1) | DE69421665T2 (pt) |
| DK (1) | DK0647654T3 (pt) |
| ES (1) | ES2139714T3 (pt) |
| FI (1) | FI113179B (pt) |
| GR (1) | GR3032603T3 (pt) |
| HU (1) | HU220672B1 (pt) |
| IL (2) | IL110932A (pt) |
| TW (1) | TW342392B (pt) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6906495B2 (en) * | 2002-05-13 | 2005-06-14 | Splashpower Limited | Contact-less power transfer |
| US7214791B2 (en) * | 2004-07-01 | 2007-05-08 | Shenzhen Hande Technology Co., Ltd. | Method for preparation of 2′-deoxy-2′, 2′-difluoro-β-cytidine or pharmaceutically acceptable salts thereof by using 1,6-anhydro-β-d-glucose as raw material |
| KR20080099263A (ko) * | 2006-02-07 | 2008-11-12 | 케마지스 리미티드 | 젬시타빈 및 관련된 중간체의 제조 방법 |
| US20070249823A1 (en) * | 2006-04-20 | 2007-10-25 | Chemagis Ltd. | Process for preparing gemcitabine and associated intermediates |
| US20080262215A1 (en) * | 2007-04-23 | 2008-10-23 | Chemagis Ltd. | Gemcitabine production process |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2270235B1 (pt) * | 1974-02-15 | 1982-09-03 | Sanofi Sa | |
| FR2315500A2 (fr) * | 1975-06-24 | 1977-01-21 | Labaz | Procede de preparation d'un diazidocyclohexanediol |
| US4526988A (en) * | 1983-03-10 | 1985-07-02 | Eli Lilly And Company | Difluoro antivirals and intermediate therefor |
| US4879377A (en) * | 1983-11-18 | 1989-11-07 | Bristol-Myers Company | Nucleoside process |
| EP0184365B1 (en) * | 1984-12-04 | 1993-08-04 | Eli Lilly And Company | Improvements in the treatment of tumors in mammals |
| US4965374A (en) * | 1987-08-28 | 1990-10-23 | Eli Lilly And Company | Process for and intermediates of 2',2'-difluoronucleosides |
| JPH0232093A (ja) * | 1988-06-08 | 1990-02-01 | Merrell Dow Pharmaceut Inc | 抗レトロウィルスジフルオロ化ヌクレオシド類 |
-
1993
- 1993-09-16 US US08/122,876 patent/US5480992A/en not_active Expired - Lifetime
-
1994
- 1994-08-11 TW TW083107347A patent/TW342392B/zh not_active IP Right Cessation
- 1994-08-15 CA CA002130124A patent/CA2130124C/en not_active Expired - Fee Related
- 1994-09-12 IL IL11093294A patent/IL110932A/xx not_active IP Right Cessation
- 1994-09-12 AT AT94306670T patent/ATE186731T1/de active
- 1994-09-12 DE DE69421665T patent/DE69421665T2/de not_active Expired - Lifetime
- 1994-09-12 DK DK94306670T patent/DK0647654T3/da active
- 1994-09-12 EP EP94306670A patent/EP0647654B1/en not_active Expired - Lifetime
- 1994-09-12 ES ES94306670T patent/ES2139714T3/es not_active Expired - Lifetime
- 1994-09-14 JP JP21985394A patent/JP3762445B2/ja not_active Expired - Fee Related
- 1994-09-15 KR KR1019940023346A patent/KR100322355B1/ko not_active IP Right Cessation
- 1994-09-15 HU HU9402646A patent/HU220672B1/hu not_active IP Right Cessation
- 1994-09-15 BR BR9403572A patent/BR9403572A/pt not_active Application Discontinuation
- 1994-09-15 FI FI944281A patent/FI113179B/fi not_active IP Right Cessation
-
1995
- 1995-05-30 US US08/453,736 patent/US5541345A/en not_active Expired - Lifetime
- 1995-05-30 US US08/453,734 patent/US5594155A/en not_active Expired - Lifetime
-
2000
- 2000-02-09 GR GR20000400301T patent/GR3032603T3/el unknown
- 2000-07-10 IL IL13724800A patent/IL137248A0/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2139714T3 (es) | 2000-02-16 |
| EP0647654A3 (pt) | 1995-05-03 |
| CA2130124A1 (en) | 1995-03-17 |
| US5480992A (en) | 1996-01-02 |
| DE69421665T2 (de) | 2000-05-25 |
| HU220672B1 (hu) | 2002-04-29 |
| HU9402646D0 (en) | 1994-12-28 |
| JP3762445B2 (ja) | 2006-04-05 |
| KR950008529A (ko) | 1995-04-19 |
| TW342392B (en) | 1998-10-11 |
| HUT72590A (en) | 1996-05-28 |
| US5541345A (en) | 1996-07-30 |
| DE69421665D1 (de) | 1999-12-23 |
| ATE186731T1 (de) | 1999-12-15 |
| FI113179B (fi) | 2004-03-15 |
| EP0647654A2 (en) | 1995-04-12 |
| GR3032603T3 (en) | 2000-05-31 |
| JPH07149783A (ja) | 1995-06-13 |
| IL137248A0 (en) | 2001-07-24 |
| EP0647654B1 (en) | 1999-11-17 |
| IL110932A (en) | 2003-05-29 |
| FI944281A0 (fi) | 1994-09-15 |
| CA2130124C (en) | 2004-08-10 |
| US5594155A (en) | 1997-01-14 |
| IL110932A0 (en) | 1994-11-28 |
| DK0647654T3 (da) | 2000-03-13 |
| KR100322355B1 (ko) | 2002-11-30 |
| FI944281A (fi) | 1995-03-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EG | Technical examination (opinion): publication of technical examination (opinion) | ||
| FC | Decision: refusal | ||
| FC | Decision: refusal | ||
| CKFC | Appeal: appeal against refusal |