BR9205939A - Derivatives of 4-aryl-3- (heteroalylureido) quinoline - Google Patents

Derivatives of 4-aryl-3- (heteroalylureido) quinoline

Info

Publication number
BR9205939A
BR9205939A BR9205939A BR9205939A BR9205939A BR 9205939 A BR9205939 A BR 9205939A BR 9205939 A BR9205939 A BR 9205939A BR 9205939 A BR9205939 A BR 9205939A BR 9205939 A BR9205939 A BR 9205939A
Authority
BR
Brazil
Prior art keywords
heteroalylureido
quinoline
aryl
derivatives
Prior art date
Application number
BR9205939A
Other languages
Portuguese (pt)
Inventor
Ernest S Hamanaka
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of BR9205939A publication Critical patent/BR9205939A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
BR9205939A 1991-04-26 1992-03-16 Derivatives of 4-aryl-3- (heteroalylureido) quinoline BR9205939A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69232391A 1991-04-26 1991-04-26
PCT/US1992/001801 WO1992019614A1 (en) 1991-04-26 1992-03-16 4-aryl-3-(heteroarylureido)quinoline derivatives

Publications (1)

Publication Number Publication Date
BR9205939A true BR9205939A (en) 1994-09-27

Family

ID=24780107

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9205939A BR9205939A (en) 1991-04-26 1992-03-16 Derivatives of 4-aryl-3- (heteroalylureido) quinoline

Country Status (20)

Country Link
EP (1) EP0590094A1 (en)
JP (1) JPH0776215B2 (en)
CN (1) CN1066068A (en)
AU (1) AU1879792A (en)
BR (1) BR9205939A (en)
CA (1) CA2108014A1 (en)
CZ (1) CZ395592A3 (en)
DE (1) DE9290049U1 (en)
FI (1) FI934710A0 (en)
HU (1) HUT65748A (en)
IE (1) IE921330A1 (en)
IL (1) IL101627A0 (en)
MX (1) MX9201916A (en)
NO (1) NO933837L (en)
NZ (1) NZ242493A (en)
PT (1) PT100426A (en)
TW (1) TW197436B (en)
WO (1) WO1992019614A1 (en)
YU (1) YU44592A (en)
ZA (1) ZA922976B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3323393A (en) * 1992-01-23 1993-09-01 Pfizer Inc. 4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxo-quinoline derivatives as antihypercholesterolemic and antiatherosclerotic agents
US5565472A (en) * 1992-12-21 1996-10-15 Pfizer Inc. 4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxo-quinoline derivatives as antihypercholesterolemic and antiatherosclerotic agents
NZ264063A (en) * 1993-08-13 1995-11-27 Nihon Nohyaku Co Ltd N-(2-phenylpyrid-3-yl)- and n-(4-phenylpyrimidin-5-yl)-n'-phenylurea derivatives and pharmaceutical compositions
US5843957A (en) * 1995-05-19 1998-12-01 Sumitomo Pharmaceuticals Company, Ltd. Naphthyridine derivatives
CN1065243C (en) * 1995-05-31 2001-05-02 住友制药株式会社 Naphthyridine derivs.
EP0947515A4 (en) * 1996-11-26 2002-10-23 Sumitomo Pharma Novel naphthyridine derivatives
CA2321237A1 (en) 1998-02-25 1999-09-02 Masami Muraoka Pyridone derivatives and process for producing the same
US6452008B2 (en) 1998-02-25 2002-09-17 Sumitomo Pharmaceuticals Company, Limited Pyridone derivatives and process for preparing the same
EP2284157A1 (en) 2003-12-12 2011-02-16 Wyeth Quinolines useful in treating cardiovascular disease
CN103601677B (en) * 2013-11-19 2015-11-18 清华大学 Prepare the method for 2-alkylthio quinoline

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE892088L (en) * 1988-07-12 1990-01-12 William Henry Deryk Morris Quinoline derivatives, their production and use
WO1991004027A1 (en) * 1989-09-15 1991-04-04 Pfizer Inc. New n-aryl and n-heteroarylamide and urea derivatives as inhibitors of acyl coenzyme a: cholesterol acyl transferase (acat)
TW205037B (en) * 1989-10-06 1993-05-01 Takeda Pharm Industry Co Ltd

Also Published As

Publication number Publication date
CN1066068A (en) 1992-11-11
YU44592A (en) 1994-12-28
NO933837L (en) 1993-10-25
ZA922976B (en) 1993-10-25
JPH0776215B2 (en) 1995-08-16
IL101627A0 (en) 1992-12-30
TW197436B (en) 1993-01-01
HU9303025D0 (en) 1994-01-28
EP0590094A1 (en) 1994-04-06
FI934710A (en) 1993-10-25
WO1992019614A1 (en) 1992-11-12
MX9201916A (en) 1992-11-01
NZ242493A (en) 1994-08-26
FI934710A0 (en) 1993-10-25
PT100426A (en) 1993-08-31
AU1879792A (en) 1992-12-21
DE9290049U1 (en) 1994-01-05
IE921330A1 (en) 1992-11-04
CZ395592A3 (en) 1994-02-16
HUT65748A (en) 1994-07-28
CA2108014A1 (en) 1992-10-27
JPH06501025A (en) 1994-01-27

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Legal Events

Date Code Title Description
EG Technical examination (opinion): publication of technical examination (opinion)
FC Decision: refusal
FC Decision: refusal