BR9006128A - Processo para a obtencao de linhas de celulas de hibridoma,bem como aplicacao de anticorpos monoclonais obtidos por tal processo - Google Patents

Processo para a obtencao de linhas de celulas de hibridoma,bem como aplicacao de anticorpos monoclonais obtidos por tal processo

Info

Publication number
BR9006128A
BR9006128A BR909006128A BR9006128A BR9006128A BR 9006128 A BR9006128 A BR 9006128A BR 909006128 A BR909006128 A BR 909006128A BR 9006128 A BR9006128 A BR 9006128A BR 9006128 A BR9006128 A BR 9006128A
Authority
BR
Brazil
Prior art keywords
hibridoma
obtaining
well
application
cell lines
Prior art date
Application number
BR909006128A
Other languages
English (en)
Portuguese (pt)
Inventor
John Wijdenes
Brigitte Morel-Fourrier
Andre Peters
Michael Kloft
Walter Sebald
Udo Schwulera
Original Assignee
Centre Regional De Transfusion
Biotest Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Regional De Transfusion, Biotest Pharma Gmbh filed Critical Centre Regional De Transfusion
Publication of BR9006128A publication Critical patent/BR9006128A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/248—IL-6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
BR909006128A 1989-12-01 1990-12-03 Processo para a obtencao de linhas de celulas de hibridoma,bem como aplicacao de anticorpos monoclonais obtidos por tal processo BR9006128A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3939706A DE3939706C1 (cg-RX-API-DMAC7.html) 1989-12-01 1989-12-01

Publications (1)

Publication Number Publication Date
BR9006128A true BR9006128A (pt) 1991-09-24

Family

ID=6394559

Family Applications (1)

Application Number Title Priority Date Filing Date
BR909006128A BR9006128A (pt) 1989-12-01 1990-12-03 Processo para a obtencao de linhas de celulas de hibridoma,bem como aplicacao de anticorpos monoclonais obtidos por tal processo

Country Status (4)

Country Link
EP (1) EP0430193A1 (cg-RX-API-DMAC7.html)
JP (1) JPH03232485A (cg-RX-API-DMAC7.html)
BR (1) BR9006128A (cg-RX-API-DMAC7.html)
DE (1) DE3939706C1 (cg-RX-API-DMAC7.html)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3525221B2 (ja) * 1993-02-17 2004-05-10 味の素株式会社 免疫抑制剤
FR2707882B1 (fr) * 1993-07-23 1997-08-01 Immunotech Sa Nouveaux kits thérapeutiques anti-médiateurs protéiques, procédé de préparation et compositions pharmaceutiques les renfermant.
US8017121B2 (en) 1994-06-30 2011-09-13 Chugai Seiyaku Kabushika Kaisha Chronic rheumatoid arthritis therapy containing IL-6 antagonist as effective component
ES2384222T3 (es) * 1994-10-07 2012-07-02 Chugai Seiyaku Kabushiki Kaisha Inhibición del crecimiento anómalo de células sinoviales utilizando un antagonista de IL-6 como principio activo
PL182089B1 (en) * 1994-10-21 2001-11-30 Chugai Pharmaceutical Co Ltd Pharmaceutic compositions for treating diseases caused by production of il-6
CN1075387C (zh) * 1994-12-29 2001-11-28 中外制药株式会社 含有il－6拮抗剂的抗肿瘤剂的作用增强剂
KR100374305B1 (ko) * 1995-01-24 2003-12-01 주식회사 엘지생명과학 인터류킨-6의존성성장반응을나타내는하이브리도마세포주및이를이용한인터류킨-6의활성도측정방법
ATE547119T1 (de) 1997-03-21 2012-03-15 Chugai Pharmaceutical Co Ltd Präventives oder therapeutisches mittel mit einem il-6-antagonisten als wirkstoff für durch sensibilisierte t-zellen vermittelte erkrankungen
FR2809182B1 (fr) * 2000-05-18 2003-08-15 Univ Rene Descartes Detection de l'il-6 pour la prevision des risques d'accouchement premature
CA2657763C (en) * 2006-08-03 2016-05-31 Vaccinex Inc. Anti-il-6 monoclonal antibodies and uses thereof
US8188235B2 (en) 2008-06-18 2012-05-29 Pfizer Inc. Antibodies to IL-6 and their uses
ES2539854T3 (es) 2010-03-02 2015-07-06 F. Hoffmann-La Roche Ag Diagnóstico y predicción precoces basados en la detección de IL-6 del síndrome de respuesta inflamatoria sistémica y sepsis en pacientes asintomáticos
ES2398646T3 (es) 2010-07-24 2013-03-20 F. Hoffmann-La Roche Ag Estabilización de la interleuquina-6 en soluciones de suero
WO2020178193A1 (en) 2019-03-01 2020-09-10 INSERM (Institut National de la Santé et de la Recherche Médicale) Method of treatment of sarcoidosis
US20220026426A1 (en) 2020-07-23 2022-01-27 Fresenius Medical Care Holdings, Inc. System for determining peritonitis using homodimer neutrophil gelatinase-associated lipocalin

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE67035B1 (en) * 1986-07-08 1996-02-21 Genetics Inst Production and use of non-glycosylated IL-6
JP2598666B2 (ja) * 1987-10-19 1997-04-09 忠三 岸本 抗ヒトｂｃｄｆモノクローナル抗体
CA1341588C (en) * 1988-01-26 2009-01-06 Michel Revel Human ifn-beta2/i1-6, its purification and use

Also Published As

Publication number Publication date
EP0430193A1 (de) 1991-06-05
DE3939706C1 (cg-RX-API-DMAC7.html) 1991-03-21
JPH03232485A (ja) 1991-10-16

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Legal Events

Date Code Title Description
EG Technical examination (opinion): publication of technical examination (opinion)
FC Decision: refusal