BR7407614D0 - PROCESS TO PREPARE BENZYL-PYRIMIDINE DERIVATIVE AND COMPOUNDS SO OBTAINED - Google Patents

PROCESS TO PREPARE BENZYL-PYRIMIDINE DERIVATIVE AND COMPOUNDS SO OBTAINED

Info

Publication number
BR7407614D0
BR7407614D0 BR7614/74A BR761474A BR7407614D0 BR 7407614 D0 BR7407614 D0 BR 7407614D0 BR 7614/74 A BR7614/74 A BR 7614/74A BR 761474 A BR761474 A BR 761474A BR 7407614 D0 BR7407614 D0 BR 7407614D0
Authority
BR
Brazil
Prior art keywords
compounds
pyrimidine derivative
prepare benzyl
benzyl
prepare
Prior art date
Application number
BR7614/74A
Other languages
Portuguese (pt)
Inventor
I Kompis
G Zanetti
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BR7407614D0 publication Critical patent/BR7407614D0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C07D207/327—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
BR7614/74A 1973-09-12 1974-09-12 PROCESS TO PREPARE BENZYL-PYRIMIDINE DERIVATIVE AND COMPOUNDS SO OBTAINED BR7407614D0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1305773A CH591456A5 (en) 1973-09-12 1973-09-12

Publications (1)

Publication Number Publication Date
BR7407614D0 true BR7407614D0 (en) 1975-07-08

Family

ID=4388903

Family Applications (1)

Application Number Title Priority Date Filing Date
BR7614/74A BR7407614D0 (en) 1973-09-12 1974-09-12 PROCESS TO PREPARE BENZYL-PYRIMIDINE DERIVATIVE AND COMPOUNDS SO OBTAINED

Country Status (28)

Country Link
JP (1) JPS6042238B2 (en)
AR (2) AR207764A1 (en)
AT (1) AT338797B (en)
BE (1) BE819773A (en)
BR (1) BR7407614D0 (en)
CA (1) CA1037476A (en)
CH (1) CH591456A5 (en)
CU (1) CU34115A (en)
DD (2) DD122785A5 (en)
DE (1) DE2443682C2 (en)
DK (1) DK135683B (en)
ES (7) ES429949A1 (en)
FI (1) FI58638C (en)
FR (1) FR2242984B1 (en)
GB (3) GB1484481A (en)
HK (1) HK181A (en)
HU (1) HU170427B (en)
IE (1) IE40523B1 (en)
IL (1) IL45510A (en)
LU (1) LU70878A1 (en)
NL (1) NL155827B (en)
NO (1) NO140858C (en)
PH (1) PH10643A (en)
PL (2) PL99159B1 (en)
SE (1) SE419443B (en)
SU (3) SU577987A3 (en)
YU (3) YU217874A (en)
ZA (1) ZA745317B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4515948A (en) * 1973-09-12 1985-05-07 Hoffmann-La Roche Inc. 2,4-Diamino-5-(4-amino and 4-dimethylamino-3,5-dimethoxy benzyl)pyrimidines
EP0001633A1 (en) * 1977-10-18 1979-05-02 The Wellcome Foundation Limited Processes for preparing tri-heterocyclic substituted methanes and their conversion into further intermediates useful in the preparation of pharmacologically active compounds
CH639273A5 (en) * 1978-09-12 1983-11-15 Hoffmann La Roche DIURETIC MEANS.
JPS5888368A (en) * 1981-11-09 1983-05-26 ザ・ウエルカム・フアウンデ−シヨン・リミテツド Manufacture of benzylpyrimidine derivative
DE3250132C2 (en) * 1981-11-09 1997-01-16 Mallinckrodt Veterinary Inc 2,4-Di:amino-5-benzyl-pyrimidine derivs. prepn.
GB2180836A (en) * 1985-09-27 1987-04-08 William James Stephen Barker Sunscreen
JPH0431685Y2 (en) * 1987-06-01 1992-07-30
CA1300166C (en) * 1987-12-03 1992-05-05 Alfredo Guerrato Process for the preparation of a benzoic acid ester
US4900859A (en) * 1987-12-03 1990-02-13 Hoffman-La Roche Inc. Process for 4-dimethylamino-3,5-dimethoxybenzaldehyde

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1103931B (en) * 1957-02-21 1961-04-06 Wellcome Found Process for the preparation of 2,4-diamino-5-benzylpyrimidine derivatives
US3485840A (en) * 1964-11-12 1969-12-23 Hoffmann La Roche 2,4-diamino - 5 - (2',4',5'-substituted benzyl) pyrimidines,intermediates and processes

Also Published As

Publication number Publication date
SU577987A3 (en) 1977-10-25
YU37153B (en) 1984-08-31
JPS6042238B2 (en) 1985-09-20
NO140858C (en) 1979-11-28
CU21022L (en) 1981-09-09
FR2242984A1 (en) 1975-04-04
HK181A (en) 1981-01-16
HU170427B (en) 1977-06-28
PL99159B1 (en) 1978-06-30
GB1484481A (en) 1977-09-01
SE7411382L (en) 1975-03-13
YU217874A (en) 1982-06-18
DK135683C (en) 1977-11-14
FR2242984B1 (en) 1977-11-04
CU34115A (en) 1983-10-04
ES437012A1 (en) 1977-04-01
SE419443B (en) 1981-08-03
ES437013A1 (en) 1977-04-01
DE2443682A1 (en) 1975-03-20
GB1484482A (en) 1977-09-01
ATA735174A (en) 1977-01-15
PL97757B1 (en) 1978-03-30
AR207764A1 (en) 1976-10-29
BE819773A (en) 1975-03-11
NL155827B (en) 1978-02-15
GB1484483A (en) 1977-09-01
NO743271L (en) 1975-04-07
AT338797B (en) 1977-09-12
IE40523B1 (en) 1979-06-20
SU609465A3 (en) 1978-05-30
YU301580A (en) 1983-04-27
ES437011A1 (en) 1977-04-01
ES429949A1 (en) 1976-10-01
ZA745317B (en) 1975-11-26
NL7411685A (en) 1975-03-14
DK135683B (en) 1977-06-06
AU7263174A (en) 1976-02-26
DK468374A (en) 1975-05-12
DE2443682C2 (en) 1983-11-10
ES437008A1 (en) 1977-04-01
ES437009A1 (en) 1977-04-01
LU70878A1 (en) 1976-08-19
DD122785A5 (en) 1976-11-05
FI256174A (en) 1975-03-13
FI58638C (en) 1981-03-10
PH10643A (en) 1977-07-22
CA1037476A (en) 1978-08-29
SU571189A3 (en) 1977-08-30
AR211387Q (en) 1977-12-15
IL45510A0 (en) 1974-11-29
YU37154B (en) 1984-08-31
JPS5053385A (en) 1975-05-12
IE40523L (en) 1975-03-12
ES437007A1 (en) 1977-04-01
FI58638B (en) 1980-11-28
YU301680A (en) 1983-04-27
NO140858B (en) 1979-08-20
DD116824A5 (en) 1975-12-12
CH591456A5 (en) 1977-09-15
IL45510A (en) 1978-08-31

Similar Documents

Publication Publication Date Title
BR7406782D0 (en) PROCESS TO PREPARE POLIETER-IMIDAS
BR7407150D0 (en) PROCESS TO STABILIZE POLYESTER-IMIDA
BR7407834D0 (en) PROCESS TO MAKE POLYETERIMIDE
BR7408111D0 (en) PROCESS TO PREPARE A POLIETER-IMIDA
BR7508186A (en) PROCESS TO ASSEPTICALLY PRE-STERILIZED PRODUCTS
BR7410908D0 (en) PROCESS TO PREPARE ZINCON PHOSPHATE
BR7408110D0 (en) PROCESS TO PREPARE A POLIETER-IMIDA
BR7403602D0 (en) PROCESS FOR OBTAINING FORMALDEIDE
BR7602965A (en) PROCESS TO PREPARE ORGANOSYLOXANS
BR7401384D0 (en) PROCESS FOR OBTAINING ALPHA-AMINOACYL-3-HALO-CEPHALOSPORINS
BR7303407D0 (en) PROCESS TO PREPARE POLYTIODIGLICOIS
AR200781A1 (en) PROCESS TO PREPARE L-LYSINE
BR7405992D0 (en) PROCESS TO SEPARATE HYDROCARBONS
BR7407614D0 (en) PROCESS TO PREPARE BENZYL-PYRIMIDINE DERIVATIVE AND COMPOUNDS SO OBTAINED
BR7407573D0 (en) 8-HYDROXY-CHEMOLINE COMPOUND AND PROCESS FOR ITS PREPARATION
BR7403335D0 (en) PROCESS TO MAKE XYLOSIS AND XYLITOL
BR7410821D0 (en) PROCESS TO PREPARE POLYOLEFINS
BR7507091A (en) PERFECT PROCESS TO PREPARE 2-MERCAPTO-BENZOTIAZO
BR7404709D0 (en) PROCESS FOR THE PREPARATION OF NEW POLYISOCIANATES
BR7605612A (en) PERFECT PROCESS TO PREPARE TRIARYL-PHOSPHINS
BR7409987A (en) PROCESS TO PREPARE ALPHA-AMINO-ALCOHOLS
BR7405089D0 (en) POLI-ETER-IMIDAS AND PROCESS TO PRODUCE THEM
AR201709A1 (en) PROCESS TO PREPARE 3-HALOCEPHALOSPORINS
BR7402732D0 (en) PROCESS FOR THE PREPARATION OF NITRO-2-HALOGENO-PHENOL
BR7400250D0 (en) PROCESS TO PRODUCE CUMENO