BR112023022889A2 - Método para induzir fibras musculares hipertróficas para produção de carne industrial - Google Patents

Método para induzir fibras musculares hipertróficas para produção de carne industrial

Info

Publication number
BR112023022889A2
BR112023022889A2 BR112023022889A BR112023022889A BR112023022889A2 BR 112023022889 A2 BR112023022889 A2 BR 112023022889A2 BR 112023022889 A BR112023022889 A BR 112023022889A BR 112023022889 A BR112023022889 A BR 112023022889A BR 112023022889 A2 BR112023022889 A2 BR 112023022889A2
Authority
BR
Brazil
Prior art keywords
muscle fibers
meat production
inducing
industrial meat
hypertrophic muscle
Prior art date
Application number
BR112023022889A
Other languages
English (en)
Inventor
Tamar Miriam Roz Eigler-Hirsh
Porat-Avinoam Ori
Tzahor Eldad
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IL283011A external-priority patent/IL283011A/en
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Publication of BR112023022889A2 publication Critical patent/BR112023022889A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L13/00—Meat products; Meat meal; Preparation or treatment thereof
    • A23L13/40—Meat products; Meat meal; Preparation or treatment thereof containing additives
    • A23L13/45—Addition of, or treatment with, microorganisms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L13/00—Meat products; Meat meal; Preparation or treatment thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/12—Light metals, i.e. alkali, alkaline earth, Be, Al, Mg
    • C12N2500/14—Calcium; Ca chelators; Calcitonin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50—Cell markers; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C12N2501/72—Transferases (EC 2.)
    • C12N2501/727—Kinases (EC 2.7.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0658—Skeletal muscle cells, e.g. myocytes, myotubes, myoblasts

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Meat, Egg Or Seafood Products (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

método para induzir fibras musculares hipertróficas para produção de carne industrial. apresenta método para induzir formação de miotubo multinucleado. o método compreendendo colocar células precursoras miogênicas de um animal de criação em contato com um inibidor de quinase de sinalização regulada extracelular (erk1/2) e/ou um regulador positivo de ca 2+ intracelular e/ou agonistas rxr/rar, melhorando a fusão e maturação miogênica.
BR112023022889A 2021-05-06 2022-05-05 Método para induzir fibras musculares hipertróficas para produção de carne industrial BR112023022889A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IL283011A IL283011A (en) 2021-05-06 2021-05-06 Methods for creating hypertrophic muscle fibers for industrial meat preparation
US202163283242P 2021-11-25 2021-11-25
PCT/IL2022/050474 WO2022234586A1 (en) 2021-05-06 2022-05-05 Method for inducing hypertrophic muscle fibers for industrial meat production

Publications (1)

Publication Number Publication Date
BR112023022889A2 true BR112023022889A2 (pt) 2024-01-23

Family

ID=81750912

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112023022889A BR112023022889A2 (pt) 2021-05-06 2022-05-05 Método para induzir fibras musculares hipertróficas para produção de carne industrial

Country Status (7)

Country Link
US (1) US20240074473A1 (pt)
EP (1) EP4334436A1 (pt)
AU (1) AU2022269414A1 (pt)
BR (1) BR112023022889A2 (pt)
CA (1) CA3216903A1 (pt)
IL (1) IL308274A (pt)
WO (1) WO2022234586A1 (pt)

Family Cites Families (20)

* Cited by examiner, † Cited by third party
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WO1998030679A1 (en) 1997-01-10 1998-07-16 Life Technologies, Inc. Embryonic stem cell serum replacement
WO1999031222A1 (en) 1997-12-18 1999-06-24 Willem Frederik Van Eelen Industrial scale production of meat from in vitro cell cultures
US8354277B2 (en) 2004-10-12 2013-01-15 Technion Research & Development Foundation Ltd. Isolated primate embryonic cells derived from extended blastocysts
CN111154726A (zh) 2013-10-30 2020-05-15 密苏里大学的策展人 可扩展性骨骼肌谱系特化和培育的方法
JP2017525351A (ja) * 2014-07-30 2017-09-07 イェダ リサーチ アンド ディベロップメント カンパニー リミテッドＹｅｄａ Ｒｅｓｅａｒｃｈ Ａｎｄ Ｄｅｖｅｌｏｐｍｅｎｔ Ｃｏ．Ｌｔｄ． 多能性幹細胞の培養用培地
EP3202894A4 (en) 2014-09-29 2018-05-23 Public University Corporation Yokohama City University Method for producing three-dimensional cell aggregates
AU2017208094A1 (en) 2016-01-14 2018-08-09 Upside Foods, Inc. Methods for extending the replicative capacity of somatic cells during an ex vivo cultivation process
IL302693A (en) 2016-07-11 2023-07-01 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd Methods and systems for growing cells in culture
CN110730615A (zh) 2017-04-09 2020-01-24 超级肉类肉本质有限公司 含培养肉的混合食品
WO2018208628A1 (en) 2017-05-06 2018-11-15 Memphis Meats, Inc. Compositions and methods for increasing the culture density of a cellular biomass within a cultivation infrastructure
CA3066060A1 (en) 2017-06-07 2018-12-13 Wild Type, Inc. Ex vivo meat production
KR20200071061A (ko) 2017-07-15 2020-06-18 알레프 팜스 리미티드 배양된 육류 조성물
US10543827B2 (en) 2017-08-30 2020-01-28 Westinghouse Air Brake Technologies Corporation System for accessing integral pressures of brake control valve
US10669524B2 (en) 2018-06-12 2020-06-02 Fork & Goode, Inc. Large scale cell culture system for making meat and associated products
EP3852742A1 (en) * 2018-09-18 2021-07-28 Société des Produits Nestlé S.A. Raf-1 kinase inhibitor compounds for skeletal muscle modulation, methods and uses thereof
WO2020131661A1 (en) * 2018-12-21 2020-06-25 Trustees of Tuffs College In vitro insect muscle as a nutrition source
BR112021012871A8 (pt) 2019-02-01 2023-04-11 Nanofiber Solutions Llc Produto de carne cultivado e método para produzir um produto de carne cultivado
US20220195392A1 (en) * 2019-04-23 2022-06-23 The Regents Of The University Of California Methods and compositions for cell culture on heterogeneous scaffolds
WO2020237021A1 (en) 2019-05-21 2020-11-26 Kent State University Animal cell lines for foods containing cultured animal cells
CA3140450A1 (en) 2019-06-14 2020-12-17 Nicholas Mullen In vitro avian food product

Also Published As

Publication number Publication date
CA3216903A1 (en) 2022-11-10
IL308274A (en) 2024-01-01
AU2022269414A1 (en) 2023-12-14
US20240074473A1 (en) 2024-03-07
WO2022234586A1 (en) 2022-11-10
EP4334436A1 (en) 2024-03-13

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