BR112023021840A2 - Método para tratar síndrome da dificuldade respiratória aguda (ards) com o uso de percursor de linhagem mesenquimal ou células-tronco - Google Patents

Método para tratar síndrome da dificuldade respiratória aguda (ards) com o uso de percursor de linhagem mesenquimal ou células-tronco

Info

Publication number
BR112023021840A2
BR112023021840A2 BR112023021840A BR112023021840A BR112023021840A2 BR 112023021840 A2 BR112023021840 A2 BR 112023021840A2 BR 112023021840 A BR112023021840 A BR 112023021840A BR 112023021840 A BR112023021840 A BR 112023021840A BR 112023021840 A2 BR112023021840 A2 BR 112023021840A2
Authority
BR
Brazil
Prior art keywords
ards
stem cells
acute respiratory
precoursor
treating acute
Prior art date
Application number
BR112023021840A
Other languages
English (en)
Portuguese (pt)
Inventor
Silviu Itescu
Original Assignee
Mesoblast Int Sarl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2021901214A external-priority patent/AU2021901214A0/en
Application filed by Mesoblast Int Sarl filed Critical Mesoblast Int Sarl
Publication of BR112023021840A2 publication Critical patent/BR112023021840A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Inorganic Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
BR112023021840A 2021-04-23 2022-04-22 Método para tratar síndrome da dificuldade respiratória aguda (ards) com o uso de percursor de linhagem mesenquimal ou células-tronco BR112023021840A2 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
AU2021901214A AU2021901214A0 (en) 2021-04-23 Method for treating acute respiratory distress syndrome (ARDS) using mesenchymal lineage precursor or stem cells
AU2021902180A AU2021902180A0 (en) 2021-07-15 Method for treating acute respiratory distress syndrome (ARDS) using mesenchymal lineage precursor or stem cells
AU2022900260A AU2022900260A0 (en) 2022-02-09 Method for treating acute respiratory distress syndrome (ARDS) in specific patients using mesenchymal lineage precursor or stem cells
AU2022900372A AU2022900372A0 (en) 2022-02-18 Method for treating acute respiratory distress syndrome (ARDS) using mesenchymal lineage precursor or stem cells
PCT/IB2022/053763 WO2022224207A1 (en) 2021-04-23 2022-04-22 Method for treating acute respiratory distress syndrome (ards) using mesenchymal lineage precursor or stem cells

Publications (1)

Publication Number Publication Date
BR112023021840A2 true BR112023021840A2 (pt) 2024-02-06

Family

ID=81585202

Family Applications (2)

Application Number Title Priority Date Filing Date
BR112023021840A BR112023021840A2 (pt) 2021-04-23 2022-04-22 Método para tratar síndrome da dificuldade respiratória aguda (ards) com o uso de percursor de linhagem mesenquimal ou células-tronco
BR112023021825A BR112023021825A2 (pt) 2021-04-23 2022-04-22 Método para tratar síndrome da angústia respiratória aguda (sara) em pacientes específicos utilizando precursores de linhagem mesenquimal ou células tronco

Family Applications After (1)

Application Number Title Priority Date Filing Date
BR112023021825A BR112023021825A2 (pt) 2021-04-23 2022-04-22 Método para tratar síndrome da angústia respiratória aguda (sara) em pacientes específicos utilizando precursores de linhagem mesenquimal ou células tronco

Country Status (8)

Country Link
US (2) US20240207323A1 (https=)
EP (2) EP4326294A1 (https=)
JP (2) JP2024516172A (https=)
KR (2) KR20240001172A (https=)
AU (2) AU2022261504A1 (https=)
BR (2) BR112023021840A2 (https=)
CA (2) CA3216129A1 (https=)
WO (2) WO2022224206A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120087868A1 (en) 2010-10-08 2012-04-12 Gabriele Todd Nanoparticle-loaded cells
SG11202004680UA (en) 2017-11-22 2020-06-29 Mesoblast Int Sarl Cellular compositions and methods of treatment i

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5486359A (en) 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US6251295B1 (en) 1998-01-08 2001-06-26 Nexell Therapeutics Inc. Method for recirculation washing of blood cells
BR112021024310A2 (pt) * 2019-06-05 2022-02-15 Univ Emory Peptidomiméticos para o tratamento de infecções por coronavírus e picornavírus

Also Published As

Publication number Publication date
BR112023021825A2 (pt) 2024-02-06
JP2024516173A (ja) 2024-04-12
US20240197787A1 (en) 2024-06-20
CA3216129A1 (en) 2022-10-27
JP2024516172A (ja) 2024-04-12
WO2022224207A1 (en) 2022-10-27
EP4326294A1 (en) 2024-02-28
KR20240001172A (ko) 2024-01-03
AU2022260822A1 (en) 2023-11-30
EP4326295A1 (en) 2024-02-28
KR20240001173A (ko) 2024-01-03
US20240207323A1 (en) 2024-06-27
AU2022261504A1 (en) 2023-11-30
CA3216121A1 (en) 2022-10-27
WO2022224206A1 (en) 2022-10-27

Similar Documents

Publication Publication Date Title
BR112022020042A2 (pt) Método para tratar hiperinflamação com o uso de células-tronco ou precursoras de linhagem mesenquimal
BR112023021840A2 (pt) Método para tratar síndrome da dificuldade respiratória aguda (ards) com o uso de percursor de linhagem mesenquimal ou células-tronco
MX2024003145A (es) Tratamiento para el sindrome de supresion del 22q11.2 con cannabidiol.
BR112022018022A2 (pt) Método para tratar doença inflamatória intestinal ii
BR112022017557A2 (pt) Método para tratar doenças pulmonares inflamatórias com o uso de células-tronco ou precursoras de linhagem mesenquimal
AR081450A1 (es) Tratamiento de sarcoidosis usando celulas madre de placenta
BR112022016448A2 (pt) Método para tratamento de doença do enxerto contra hospedeiro crônica
CO2021002704A2 (es) Método de producción de precursores neuronales entéricos
BR112022007721A2 (pt) Método para o tratamento da demência
BR112022017560A2 (pt) Método para tratar doença inflamatória intestinal i
BR112023020669A2 (pt) Terapias de combinação para o tratamento de câncer
BR112014016950A2 (pt) métodos de promoção da cicatrização de úlceras diabéticas utilizando beta-hidróxi-beta-metilbutirato com arginina e glutamina
CR20200061A (es) Tratamiento con obinutuzumab nuevo subgrupo de pacientes con nuevo linfoma de células b grandes difusas (dlbcl)
BR112020010856A8 (pt) Uso de conjugado de anticorpo anti-her2-fármaco no tratamento de carcinoma urotelial
BR112016007487A2 (pt) composições compreendendo citrulina e leucina e seu uso no tratamento de diabetes e de síndrome meta-bólica
BR112016023823A2 (pt) método para produção de um produto de fermentação
MX2024005253A (es) Metodos para tratar crecimiento celular anormal.
BR112021017878A2 (pt) Carbonato de magnésio com superfície reagida, sistema de liberação, formulação de cuidados domiciliares, métodos para preparar um carbonato de magnésio com superfície reagida e para preparar um sistema de liberação, e, uso de um carbonato de magnésio com superfície reagida e de um sistema de liberação
BR112022026044A2 (pt) Tratamento de síndrome do x frágil com canabidiol
BR112022021006A2 (pt) Métodos para reduzir ou prevenir a colonização de clostridioides difficile
BR112023026559A2 (pt) Formas cristalinas de trofinetida
CL2022002239A1 (es) Tafoxiparina para el tratamiento de la preeclampsia
BR112015017583A2 (pt) n-metilserotonina e substâncias relacionadas para utilização em tratamento/diminuição da ocorrência de ondas de calor associadas a menopausa
ECSP21040508A (es) Moduladores de la expresión de foxp3
SUN The protective effect of quercetin on vascular endothelial progenitor cells by regulating PI3K/Akt signaling pathway and its mechanisms