BR112023021531A2 - Implante de tecido ósseo artificial híbrido absorvente de vibrações mecânicas, cuja estrutura arquitetônica imita o osso trabecular, permitindo a saturação da medula óssea, sangue e nutrientes, suportando a regeneração autologica, que pode ser utilizada com estruturas de titânio - Google Patents
Implante de tecido ósseo artificial híbrido absorvente de vibrações mecânicas, cuja estrutura arquitetônica imita o osso trabecular, permitindo a saturação da medula óssea, sangue e nutrientes, suportando a regeneração autologica, que pode ser utilizada com estruturas de titânioInfo
- Publication number
- BR112023021531A2 BR112023021531A2 BR112023021531A BR112023021531A BR112023021531A2 BR 112023021531 A2 BR112023021531 A2 BR 112023021531A2 BR 112023021531 A BR112023021531 A BR 112023021531A BR 112023021531 A BR112023021531 A BR 112023021531A BR 112023021531 A2 BR112023021531 A2 BR 112023021531A2
- Authority
- BR
- Brazil
- Prior art keywords
- bone
- supporting
- tissue implant
- nutrients
- blood
- Prior art date
Links
- 210000000988 bone and bone Anatomy 0.000 title abstract 4
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical group [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 title abstract 3
- 239000007943 implant Substances 0.000 title abstract 3
- 210000004369 blood Anatomy 0.000 title abstract 2
- 239000008280 blood Substances 0.000 title abstract 2
- 210000001185 bone marrow Anatomy 0.000 title abstract 2
- 235000015097 nutrients Nutrition 0.000 title abstract 2
- 230000008929 regeneration Effects 0.000 title abstract 2
- 238000011069 regeneration method Methods 0.000 title abstract 2
- 238000000576 coating method Methods 0.000 abstract 2
- 230000005540 biological transmission Effects 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 230000008021 deposition Effects 0.000 abstract 1
- 238000001125 extrusion Methods 0.000 abstract 1
- 239000003102 growth factor Substances 0.000 abstract 1
- 230000008595 infiltration Effects 0.000 abstract 1
- 238000001764 infiltration Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000000278 osteoconductive effect Effects 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 210000001519 tissue Anatomy 0.000 abstract 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/58—Materials at least partially resorbable by the body
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y80/00—Products made by additive manufacturing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A61F2002/2835—Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
- A61F2002/3006—Properties of materials and coating materials
- A61F2002/30062—(bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00179—Ceramics or ceramic-like structures
- A61F2310/00293—Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/24—Materials or treatment for tissue regeneration for joint reconstruction
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Biomedical Technology (AREA)
- Manufacturing & Machinery (AREA)
- Vascular Medicine (AREA)
- Inorganic Chemistry (AREA)
- Composite Materials (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dispersion Chemistry (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
Abstract
implante de tecido ósseo artificial híbrido absorvente de vibrações mecânicas, cuja estrutura arquitetônica imita o osso trabecular, permitindo a saturação da medula óssea, sangue e nutrientes, suportando a regeneração autologica, que pode ser utilizada com estruturas de titânio. esta invenção é baseada na criação de uma estrutura de arcabouço de polímero como resultado da combinação proporcional de ß-fosfato tricálcico (ß-tcp) que aumentará o efeito tridimensional e osteocondutor, permitindo/suportando a infiltração celular, usando deposição por extrusão, em outras palavras, processo de fabricação adicionado e com solução de ha tamponada fisiológica com o método de revestimento profundo e aumentando a taxa de transmissão de fatores de crescimento como resultado do revestimento e expansão de suas áreas com o implante de tecido biológico, o que permite seu uso com placas de malha de titânio ou estruturas contornadas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
TR2021/006756A TR202106756A2 (tr) | 2021-04-17 | 2021-04-17 | Mi̇mari̇ yapisi trabeküler kemi̇ği̇ takli̇t eden, kemi̇k i̇li̇ği̇, kan ve besi̇nleri̇n doygunluğuna i̇zi̇n veren, otolog rejenerasyonu destekleyen, ti̇tanyum yapilar i̇le bi̇rli̇kte kullanilabi̇len hybrid, mekani̇k ti̇treşi̇mleri̇ absorbe eden yapay kemi̇k doku i̇mplanti |
PCT/TR2021/051516 WO2022220766A1 (en) | 2021-04-17 | 2021-12-26 | Hybrid, artificial bone tissue implant absorbing mechanical vibrations, whose architectural structure imitates trabecular bone, allowing the saturation of bone marrow, blood, and nutrients, supporting autological regeneration, which can be used with titanium structures |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112023021531A2 true BR112023021531A2 (pt) | 2023-12-19 |
Family
ID=77515866
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112023021531A BR112023021531A2 (pt) | 2021-04-17 | 2021-12-26 | Implante de tecido ósseo artificial híbrido absorvente de vibrações mecânicas, cuja estrutura arquitetônica imita o osso trabecular, permitindo a saturação da medula óssea, sangue e nutrientes, suportando a regeneração autologica, que pode ser utilizada com estruturas de titânio |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP4323028A4 (pt) |
CN (1) | CN117202943A (pt) |
AU (1) | AU2021440208A1 (pt) |
BR (1) | BR112023021531A2 (pt) |
CA (1) | CA3215063A1 (pt) |
TR (1) | TR202106756A2 (pt) |
WO (1) | WO2022220766A1 (pt) |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102619833B1 (ko) * | 2015-10-09 | 2024-01-03 | 오씨폼 에이피에스 | 3d 인쇄를 위한 공급 원료 및 이의 용도 |
GB201600385D0 (en) * | 2016-01-08 | 2016-02-24 | Ucl Business Plc | Osteochondral scaffold |
WO2018078130A1 (en) * | 2016-10-28 | 2018-05-03 | Paul Gatenholm | Preparation and applications of 3d bioprinting bioinks for repair of bone defects, based on cellulose nanofibrils hydrogels with natural or synthetic calcium phosphate particles |
CN111973811B (zh) * | 2020-08-28 | 2022-05-17 | 西安点云生物科技有限公司 | 一种含锌人工骨及其制备方法 |
CN112590203B (zh) * | 2020-12-16 | 2022-09-30 | 中国科学院深圳先进技术研究院 | 一种负载药物、活性因子、细胞的可控梯度支架及其3d打印方法和专用多喷头3d打印机 |
-
2021
- 2021-04-17 TR TR2021/006756A patent/TR202106756A2/tr unknown
- 2021-12-26 EP EP21937120.0A patent/EP4323028A4/en active Pending
- 2021-12-26 BR BR112023021531A patent/BR112023021531A2/pt unknown
- 2021-12-26 AU AU2021440208A patent/AU2021440208A1/en active Pending
- 2021-12-26 WO PCT/TR2021/051516 patent/WO2022220766A1/en active Application Filing
- 2021-12-26 CA CA3215063A patent/CA3215063A1/en active Pending
- 2021-12-26 CN CN202180097193.5A patent/CN117202943A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
CA3215063A1 (en) | 2022-10-20 |
CN117202943A (zh) | 2023-12-08 |
AU2021440208A1 (en) | 2023-10-26 |
TR202106756A2 (tr) | 2021-05-21 |
EP4323028A4 (en) | 2024-05-15 |
EP4323028A1 (en) | 2024-02-21 |
WO2022220766A1 (en) | 2022-10-20 |
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