BR112023021343A2 - Voxelização eficiente para aprendizagem profunda - Google Patents

Voxelização eficiente para aprendizagem profunda

Info

Publication number
BR112023021343A2
BR112023021343A2 BR112023021343A BR112023021343A BR112023021343A2 BR 112023021343 A2 BR112023021343 A2 BR 112023021343A2 BR 112023021343 A BR112023021343 A BR 112023021343A BR 112023021343 A BR112023021343 A BR 112023021343A BR 112023021343 A2 BR112023021343 A2 BR 112023021343A2
Authority
BR
Brazil
Prior art keywords
atom
voxel
atoms
voxels
protein
Prior art date
Application number
BR112023021343A
Other languages
English (en)
Portuguese (pt)
Inventor
Hong Gao
Kai-How FARH
Tobias Hamp
Original Assignee
Illumina Cambridge Ltd
Illumina Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US17/703,935 external-priority patent/US20220336056A1/en
Application filed by Illumina Cambridge Ltd, Illumina Inc filed Critical Illumina Cambridge Ltd
Publication of BR112023021343A2 publication Critical patent/BR112023021343A2/pt

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B15/00—ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00—Computing arrangements based on biological models
    • G06N3/02—Neural networks
    • G06N3/04—Architecture, e.g. interconnection topology
    • G06N3/045—Combinations of networks
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20—Supervised data analysis
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00—Computing arrangements based on biological models
    • G06N3/02—Neural networks
    • G06N3/04—Architecture, e.g. interconnection topology
    • G06N3/044—Recurrent networks, e.g. Hopfield networks
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00—Computing arrangements based on biological models
    • G06N3/02—Neural networks
    • G06N3/08—Learning methods
    • G06N3/084—Backpropagation, e.g. using gradient descent

Landscapes

  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Theoretical Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Data Mining & Analysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Evolutionary Computation (AREA)
  • Molecular Biology (AREA)
  • Artificial Intelligence (AREA)
  • Software Systems (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biotechnology (AREA)
  • Evolutionary Biology (AREA)
  • Computing Systems (AREA)
  • Biomedical Technology (AREA)
  • Mathematical Physics (AREA)
  • General Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Computational Linguistics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Genetics & Genomics (AREA)
  • Databases & Information Systems (AREA)
  • Bioethics (AREA)
  • Public Health (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Epidemiology (AREA)
  • Information Retrieval, Db Structures And Fs Structures Therefor (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Image Processing (AREA)
  • Image Generation (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
BR112023021343A 2021-04-15 2022-04-14 Voxelização eficiente para aprendizagem profunda BR112023021343A2 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163175495P 2021-04-15 2021-04-15
US202163175767P 2021-04-16 2021-04-16
US17/703,935 US20220336056A1 (en) 2021-04-15 2022-03-24 Multi-channel protein voxelization to predict variant pathogenicity using deep convolutional neural networks
US17/703,958 US20220336057A1 (en) 2021-04-15 2022-03-24 Efficient voxelization for deep learning
PCT/US2022/024918 WO2022221593A1 (fr) 2021-04-15 2022-04-14 Voxélisation efficace pour apprentissage en profondeur

Publications (1)

Publication Number Publication Date
BR112023021343A2 true BR112023021343A2 (pt) 2023-12-19

Family

ID=81448684

Family Applications (2)

Application Number Title Priority Date Filing Date
BR112023021266A BR112023021266A2 (pt) 2021-04-15 2022-04-14 Voxelização de proteína de múltiplos canais para predizer a patogenicidade variante com o uso de redes neurais convolucionais profundas
BR112023021343A BR112023021343A2 (pt) 2021-04-15 2022-04-14 Voxelização eficiente para aprendizagem profunda

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BR112023021266A BR112023021266A2 (pt) 2021-04-15 2022-04-14 Voxelização de proteína de múltiplos canais para predizer a patogenicidade variante com o uso de redes neurais convolucionais profundas

Country Status (9)

Country Link
EP (2) EP4323991A1 (fr)
JP (2) JP2024513995A (fr)
KR (2) KR20230170680A (fr)
AU (2) AU2022259667A1 (fr)
BR (2) BR112023021266A2 (fr)
CA (2) CA3215520A1 (fr)
IL (2) IL307661A (fr)
MX (2) MX2023012227A (fr)
WO (2) WO2022221591A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116153404B (zh) * 2023-02-28 2023-08-15 成都信息工程大学 一种单细胞ATAC-seq数据分析方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2018350891B9 (en) * 2017-10-16 2022-05-19 Illumina, Inc. Deep learning-based techniques for training deep convolutional neural networks
WO2019084559A1 (fr) * 2017-10-27 2019-05-02 Apostle, Inc. Prédiction d'impact pathogène lié au cancer de mutations somatiques à l'aide de procédés basés sur un apprentissage profond
CN110245685B (zh) * 2019-05-15 2022-03-25 清华大学 基因组单位点变异致病性的预测方法、系统及存储介质

Also Published As

Publication number Publication date
WO2022221593A1 (fr) 2022-10-20
EP4323991A1 (fr) 2024-02-21
CA3215514A1 (fr) 2022-10-20
MX2023012226A (es) 2024-01-08
KR20230170679A (ko) 2023-12-19
CA3215520A1 (fr) 2022-10-20
AU2022258691A1 (en) 2023-10-26
AU2022259667A1 (en) 2023-10-26
BR112023021266A2 (pt) 2023-12-12
KR20230170680A (ko) 2023-12-19
EP4323989A1 (fr) 2024-02-21
JP2024513995A (ja) 2024-03-27
IL307667A (en) 2023-12-01
WO2022221591A1 (fr) 2022-10-20
MX2023012227A (es) 2024-01-08
JP2024514894A (ja) 2024-04-03
IL307661A (en) 2023-12-01

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