CA3215520A1 - Voxelisation efficace pour apprentissage en profondeur - Google Patents
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
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Abstract
La technologie divulguée consiste à déterminer efficacement quels atomes dans une protéine sont les plus proches de voxels dans une grille. Les atomes ont des coordonnées d'atomes tridimensionnelles (3D), et les voxels ont des coordonnées de voxels 3D. La technologie divulguée génère une mise en correspondance d'atomes sur voxels qui met en correspondance, sur chacun des atomes, un voxel contenant sélectionné en fonction des coordonnées d'atome 3D correspondantes d'un atome particulier de la protéine par rapport aux coordonnées de voxel 3D dans la grille. La technologie divulguée génère une mise en correspondance voxel sur atomes qui met en correspondance, à chacun des voxels, un sous-ensemble des atomes. Le sous-ensemble des atomes mis en correspondance avec un voxel particulier dans la grille comprend les atomes dans la protéine qui sont mis en correspondance sur le voxel particulier par mise en correspondance atome sur voxels. La technologie divulguée consiste à utiliser la mise en correspondance voxel sur atomes pour déterminer, pour chacun des voxels, un atome le plus proche dans la protéine.
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163175495P | 2021-04-15 | 2021-04-15 | |
| US63/175,495 | 2021-04-15 | ||
| US202163175767P | 2021-04-16 | 2021-04-16 | |
| US63/175,767 | 2021-04-16 | ||
| US17/703,935 US20220336056A1 (en) | 2021-04-15 | 2022-03-24 | Multi-channel protein voxelization to predict variant pathogenicity using deep convolutional neural networks |
| US17/703,958 | 2022-03-24 | ||
| US17/703,958 US20220336057A1 (en) | 2021-04-15 | 2022-03-24 | Efficient voxelization for deep learning |
| US17/703,935 | 2022-03-24 | ||
| PCT/US2022/024918 WO2022221593A1 (fr) | 2021-04-15 | 2022-04-14 | Voxélisation efficace pour apprentissage en profondeur |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3215520A1 true CA3215520A1 (fr) | 2022-10-20 |
Family
ID=81448684
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3215520A Pending CA3215520A1 (fr) | 2021-04-15 | 2022-04-14 | Voxelisation efficace pour apprentissage en profondeur |
| CA3215514A Pending CA3215514A1 (fr) | 2021-04-15 | 2022-04-14 | Voxelisation de proteine a canaux multiples pour predire une pathogenicite d'un variant a l'aide de reseaux neuronaux convolutifs profonds |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3215514A Pending CA3215514A1 (fr) | 2021-04-15 | 2022-04-14 | Voxelisation de proteine a canaux multiples pour predire une pathogenicite d'un variant a l'aide de reseaux neuronaux convolutifs profonds |
Country Status (9)
| Country | Link |
|---|---|
| EP (2) | EP4323991A1 (fr) |
| JP (2) | JP2024513995A (fr) |
| KR (2) | KR20230170680A (fr) |
| AU (2) | AU2022259667A1 (fr) |
| BR (2) | BR112023021266A2 (fr) |
| CA (2) | CA3215520A1 (fr) |
| IL (2) | IL307661A (fr) |
| MX (2) | MX2023012227A (fr) |
| WO (2) | WO2022221591A1 (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116153404B (zh) * | 2023-02-28 | 2023-08-15 | 成都信息工程大学 | 一种单细胞ATAC-seq数据分析方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2018350891B9 (en) * | 2017-10-16 | 2022-05-19 | Illumina, Inc. | Deep learning-based techniques for training deep convolutional neural networks |
| WO2019084559A1 (fr) * | 2017-10-27 | 2019-05-02 | Apostle, Inc. | Prédiction d'impact pathogène lié au cancer de mutations somatiques à l'aide de procédés basés sur un apprentissage profond |
| CN110245685B (zh) * | 2019-05-15 | 2022-03-25 | 清华大学 | 基因组单位点变异致病性的预测方法、系统及存储介质 |
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2022
- 2022-04-14 JP JP2023563033A patent/JP2024513995A/ja active Pending
- 2022-04-14 AU AU2022259667A patent/AU2022259667A1/en active Pending
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- 2022-04-14 WO PCT/US2022/024918 patent/WO2022221593A1/fr active Application Filing
- 2022-04-14 IL IL307667A patent/IL307667A/en unknown
- 2022-04-14 CA CA3215520A patent/CA3215520A1/fr active Pending
- 2022-04-14 AU AU2022258691A patent/AU2022258691A1/en active Pending
- 2022-04-14 EP EP22720250.4A patent/EP4323989A1/fr active Pending
- 2022-04-14 MX MX2023012226A patent/MX2023012226A/es unknown
- 2022-04-14 CA CA3215514A patent/CA3215514A1/fr active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2022221593A1 (fr) | 2022-10-20 |
| EP4323991A1 (fr) | 2024-02-21 |
| CA3215514A1 (fr) | 2022-10-20 |
| MX2023012226A (es) | 2024-01-08 |
| KR20230170679A (ko) | 2023-12-19 |
| AU2022258691A1 (en) | 2023-10-26 |
| AU2022259667A1 (en) | 2023-10-26 |
| BR112023021266A2 (pt) | 2023-12-12 |
| KR20230170680A (ko) | 2023-12-19 |
| BR112023021343A2 (pt) | 2023-12-19 |
| EP4323989A1 (fr) | 2024-02-21 |
| JP2024513995A (ja) | 2024-03-27 |
| IL307667A (en) | 2023-12-01 |
| WO2022221591A1 (fr) | 2022-10-20 |
| MX2023012227A (es) | 2024-01-08 |
| JP2024514894A (ja) | 2024-04-03 |
| IL307661A (en) | 2023-12-01 |
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