BR112023018246A2 - Formas de sal e sólidas de um inibidor de cinase - Google Patents

Formas de sal e sólidas de um inibidor de cinase

Info

Publication number
BR112023018246A2
BR112023018246A2 BR112023018246A BR112023018246A BR112023018246A2 BR 112023018246 A2 BR112023018246 A2 BR 112023018246A2 BR 112023018246 A BR112023018246 A BR 112023018246A BR 112023018246 A BR112023018246 A BR 112023018246A BR 112023018246 A2 BR112023018246 A2 BR 112023018246A2
Authority
BR
Brazil
Prior art keywords
salt
solid forms
forms
kinase inhibitor
compound
Prior art date
Application number
BR112023018246A
Other languages
English (en)
Portuguese (pt)
Inventor
Brian Heinrich
Caitlin Kinkema
Christopher Lee
Aubrey Medendorp Clare
Erika Butler
Hui Li
Lauren Maceachern
Nimita Dave
Dong Si Tuan
Original Assignee
Blueprint Medicines Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Blueprint Medicines Corp filed Critical Blueprint Medicines Corp
Publication of BR112023018246A2 publication Critical patent/BR112023018246A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
BR112023018246A 2021-03-10 2022-03-10 Formas de sal e sólidas de um inibidor de cinase BR112023018246A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163159107P 2021-03-10 2021-03-10
US202163208641P 2021-06-09 2021-06-09
PCT/US2022/019776 WO2022192558A1 (en) 2021-03-10 2022-03-10 Salt and solid forms of a kinase inhibitor

Publications (1)

Publication Number Publication Date
BR112023018246A2 true BR112023018246A2 (pt) 2024-01-30

Family

ID=81074313

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112023018246A BR112023018246A2 (pt) 2021-03-10 2022-03-10 Formas de sal e sólidas de um inibidor de cinase

Country Status (11)

Country Link
US (1) US20240254130A1 (https=)
EP (1) EP4305036A1 (https=)
JP (1) JP2024509276A (https=)
KR (1) KR20240013720A (https=)
AU (1) AU2022234314A1 (https=)
BR (1) BR112023018246A2 (https=)
CA (1) CA3211477A1 (https=)
CR (1) CR20230479A (https=)
IL (1) IL305791A (https=)
MX (1) MX2023010606A (https=)
WO (1) WO2022192558A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230391780A1 (en) * 2020-10-14 2023-12-07 Blueprint Medicines Corporation Compositions and methods for treating kit- and pdgfra-mediated diseases
WO2024171143A1 (en) 2023-02-17 2024-08-22 Assia Chemical Industries Ltd. Salts and solid forms of elenestinib

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112021020441A2 (pt) 2019-04-12 2021-12-14 Blueprint Medicines Corp Derivados de pirrolotriazina para tratar doenças mediadas por kit e pdgfra

Also Published As

Publication number Publication date
US20240254130A1 (en) 2024-08-01
EP4305036A1 (en) 2024-01-17
JP2024509276A (ja) 2024-02-29
CA3211477A1 (en) 2022-09-15
AU2022234314A1 (en) 2023-09-28
MX2023010606A (es) 2023-10-19
KR20240013720A (ko) 2024-01-30
CR20230479A (es) 2024-03-08
WO2022192558A1 (en) 2022-09-15
IL305791A (en) 2023-11-01

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