BR112022024645A2 - Sistema e método para tratamento de sangue extracorpóreo - Google Patents
Sistema e método para tratamento de sangue extracorpóreoInfo
- Publication number
- BR112022024645A2 BR112022024645A2 BR112022024645A BR112022024645A BR112022024645A2 BR 112022024645 A2 BR112022024645 A2 BR 112022024645A2 BR 112022024645 A BR112022024645 A BR 112022024645A BR 112022024645 A BR112022024645 A BR 112022024645A BR 112022024645 A2 BR112022024645 A2 BR 112022024645A2
- Authority
- BR
- Brazil
- Prior art keywords
- blood
- dialysate fluid
- concentration
- pump
- circuit
- Prior art date
Links
- 239000008280 blood Substances 0.000 title abstract 13
- 210000004369 blood Anatomy 0.000 title abstract 13
- 238000000034 method Methods 0.000 title abstract 5
- 239000012530 fluid Substances 0.000 abstract 7
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 abstract 2
- 150000002576 ketones Chemical class 0.000 abstract 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 230000017531 blood circulation Effects 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 238000000502 dialysis Methods 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3607—Regulation parameters
- A61M1/3609—Physical characteristics of the blood, e.g. haematocrit, urea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1601—Control or regulation
- A61M1/1603—Regulation parameters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1654—Dialysates therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3623—Means for actively controlling temperature of blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2230/00—Measuring parameters of the user
- A61M2230/20—Blood composition characteristics
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- External Artificial Organs (AREA)
Abstract
SISTEMA E MÉTODO PARA TRATAMENTO DE SANGUE EXTRACORPÓREO. O presente pedido refere-se a um sistema de tratamento de sangue extracorpóreo (50) para tratar um sujeito, o sistema compreendendo: um circuito de sangue extracorpóreo (52); um circuito de fluido de dialisato (54); sendo o referido circuito de sangue extracorpóreo e o circuito de fluido de dialisato divididos por uma membrana (56) de uma unidade de filtração (58); pelo menos uma bomba de sangue (60) para controlar o fluxo de sangue através do circuito de sangue; pelo menos uma bomba de fluido de dialisato (62) para controlar o fluxo de fluido de dialisato através do circuito de fluido de dialisato (54); uma unidade de computação do sistema (64) operativamente conectada à bomba de sangue e à bomba de fluido de dialisato, tendo a referida unidade de computação do sistema pelo menos um meio de entrada; em que a unidade de computação do sistema está adaptada para receber uma concentração sanguínea desejada GLNb de glutamina, para receber uma concentração sanguínea desejada GLUCOSEb de glicose e para receber uma concentração sanguínea desejada de um corpo cetônico KETONEb; a unidade de computação do sistema sendo adaptada para controlar a referida bomba de sangue e a referida bomba de fluido de dialisato de modo que o valor de concentração real GLNa de glutamina seja trazido para GLNb e o valor de concentração real GLUCOSEa de glicose seja trazido para Db, e o valor real da concentração de corpos cetônicos é trazido para KETONEa. O pedido também se refere a um conjunto terapêutico para uso no sistema de tratamento de sangue extracorpóreo, um método para tratamento de câncer usando o sistema, um controlador para controlar o método, bem como um líquido de diálise adequado para o método.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE2050621 | 2020-06-01 | ||
| PCT/EP2021/064592 WO2021245040A1 (en) | 2020-06-01 | 2021-06-01 | System and method for extracorporeal blood treatment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112022024645A2 true BR112022024645A2 (pt) | 2022-12-27 |
Family
ID=76532163
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112022024645A BR112022024645A2 (pt) | 2020-06-01 | 2021-06-01 | Sistema e método para tratamento de sangue extracorpóreo |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP4157390A1 (pt) |
| JP (1) | JP2023528588A (pt) |
| KR (1) | KR20230019159A (pt) |
| CN (1) | CN115996769A (pt) |
| AU (1) | AU2021286159A1 (pt) |
| BR (1) | BR112022024645A2 (pt) |
| CA (1) | CA3180461A1 (pt) |
| MX (1) | MX2022015171A (pt) |
| WO (1) | WO2021245040A1 (pt) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2022402355A1 (en) * | 2021-12-01 | 2024-06-20 | Gambro Lundia Ab | Dialysis fluid comprising ketone bodies for the treatment of cancer |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5091094A (en) * | 1985-06-24 | 1992-02-25 | Veech Richard L | Hemodialysis processes & hemodialysis solutions |
| US4780191A (en) | 1987-06-26 | 1988-10-25 | Massachusetts Institute Of Technology | L-glutamine sensor |
| US5190863A (en) | 1990-06-29 | 1993-03-02 | Miles Inc. | Composition for determining the presence or concentration of D-β-hydroxybutyrate |
| US5441636A (en) | 1993-02-12 | 1995-08-15 | Cobe Laboratories, Inc. | Integrated blood treatment fluid module |
| US5910252A (en) | 1993-02-12 | 1999-06-08 | Cobe Laboratories, Inc. | Technique for extracorporeal treatment of blood |
| JP2677154B2 (ja) | 1993-03-08 | 1997-11-17 | 日東紡績株式会社 | 総ケトン体の測定方法および測定試薬 |
| US6338790B1 (en) | 1998-10-08 | 2002-01-15 | Therasense, Inc. | Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator |
| US6591125B1 (en) | 2000-06-27 | 2003-07-08 | Therasense, Inc. | Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator |
| US7415299B2 (en) | 2003-04-18 | 2008-08-19 | The Regents Of The University Of California | Monitoring method and/or apparatus |
| US20120296253A1 (en) | 2009-12-10 | 2012-11-22 | Edward Henry Mathews | Haemodialysis machine retrofit and control installation and use thereof for the treatment of proliferative disorders |
| ES2387534T3 (es) | 2010-04-19 | 2012-09-25 | Gambro Lundia Ab | Aparato de diálisis |
| WO2015084189A1 (en) | 2013-12-05 | 2015-06-11 | Victoria Link Limited | Methods of detecting and measuring glutamine and analogues thereof, and methods related thereto |
| US20160168619A1 (en) | 2014-12-11 | 2016-06-16 | Shufang Tao | Colorimetric assay for l-glutamine and related assay kit |
| CN107533028A (zh) | 2015-05-07 | 2018-01-02 | 聚合物技术系统公司 | 用于电化学酮检测和测量的系统和方法 |
| FR3060859B1 (fr) | 2016-12-21 | 2019-05-31 | Centre National De La Recherche Scientifique | Bio-electrode pour la detection et/ou l'oxydation du glucose et son procede de fabrication et dispositif la comprenant. |
| WO2018114309A1 (en) | 2016-12-23 | 2018-06-28 | Katholieke Universiteit Leuven | 3-hydroxybutyrate alone or in combination for use in the treatment of critical care treatment |
-
2021
- 2021-06-01 JP JP2022572430A patent/JP2023528588A/ja active Pending
- 2021-06-01 WO PCT/EP2021/064592 patent/WO2021245040A1/en unknown
- 2021-06-01 CN CN202180039728.3A patent/CN115996769A/zh active Pending
- 2021-06-01 EP EP21733724.5A patent/EP4157390A1/en active Pending
- 2021-06-01 AU AU2021286159A patent/AU2021286159A1/en active Pending
- 2021-06-01 CA CA3180461A patent/CA3180461A1/en active Pending
- 2021-06-01 BR BR112022024645A patent/BR112022024645A2/pt unknown
- 2021-06-01 KR KR1020227046315A patent/KR20230019159A/ko active Search and Examination
- 2021-06-01 MX MX2022015171A patent/MX2022015171A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2021245040A1 (en) | 2021-12-09 |
| EP4157390A1 (en) | 2023-04-05 |
| CA3180461A1 (en) | 2021-12-09 |
| MX2022015171A (es) | 2023-01-16 |
| JP2023528588A (ja) | 2023-07-05 |
| CN115996769A (zh) | 2023-04-21 |
| AU2021286159A1 (en) | 2023-02-02 |
| KR20230019159A (ko) | 2023-02-07 |
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