BR112022021001A2 - Métodos e sistema para validar as medições de citometria de fluxo - Google Patents
Métodos e sistema para validar as medições de citometria de fluxoInfo
- Publication number
- BR112022021001A2 BR112022021001A2 BR112022021001A BR112022021001A BR112022021001A2 BR 112022021001 A2 BR112022021001 A2 BR 112022021001A2 BR 112022021001 A BR112022021001 A BR 112022021001A BR 112022021001 A BR112022021001 A BR 112022021001A BR 112022021001 A2 BR112022021001 A2 BR 112022021001A2
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- flow cytometry
- cytometry measurements
- validate
- validate flow
- Prior art date
Links
- 238000005259 measurement Methods 0.000 title abstract 3
- 238000000684 flow cytometry Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000010200 validation analysis Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1434—Optical arrangements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56972—White blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/38—Diluting, dispersing or mixing samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/1012—Calibrating particle analysers; References therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
- G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1006—Investigating individual particles for cytology
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
- G01N2333/7051—T-cell receptor (TcR)-CD3 complex
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70596—Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Dispersion Chemistry (AREA)
- Virology (AREA)
- Food Science & Technology (AREA)
- Zoology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Optics & Photonics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Optical Measuring Cells (AREA)
- Measuring Volume Flow (AREA)
Abstract
MÉTODOS E SISTEMA PARA VALIDAR AS MEDIÇÕES DE CITOMETRIA DE FLUXO. A presente invenção refere-se a métodos de validação e sistemas para caracterizar acredibilidade e reprodutividade de medições, feitas por um instrumento analítico baseado em fluorescência.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202063013098P | 2020-04-21 | 2020-04-21 | |
PCT/IB2021/053301 WO2021214690A1 (en) | 2020-04-21 | 2021-04-21 | Methods and system for validating flow cytometry measurements |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112022021001A2 true BR112022021001A2 (pt) | 2022-12-06 |
Family
ID=75919345
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112022021001A BR112022021001A2 (pt) | 2020-04-21 | 2021-04-21 | Métodos e sistema para validar as medições de citometria de fluxo |
Country Status (11)
Country | Link |
---|---|
US (1) | US20230273110A1 (pt) |
EP (1) | EP4139686A1 (pt) |
JP (1) | JP2023534780A (pt) |
KR (1) | KR20230026301A (pt) |
CN (1) | CN115698716A (pt) |
AU (1) | AU2021260997A1 (pt) |
BR (1) | BR112022021001A2 (pt) |
CA (1) | CA3175796A1 (pt) |
IL (1) | IL297459A (pt) |
MX (1) | MX2022012948A (pt) |
WO (1) | WO2021214690A1 (pt) |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG11201907917XA (en) | 2017-02-28 | 2019-09-27 | University Of Central Florida Research Foundation Inc | Pm21 particles to improve bone marrow homing of nk cells |
-
2021
- 2021-04-21 KR KR1020227040558A patent/KR20230026301A/ko active Search and Examination
- 2021-04-21 CN CN202180042210.5A patent/CN115698716A/zh active Pending
- 2021-04-21 AU AU2021260997A patent/AU2021260997A1/en active Pending
- 2021-04-21 WO PCT/IB2021/053301 patent/WO2021214690A1/en active Application Filing
- 2021-04-21 BR BR112022021001A patent/BR112022021001A2/pt unknown
- 2021-04-21 IL IL297459A patent/IL297459A/en unknown
- 2021-04-21 MX MX2022012948A patent/MX2022012948A/es unknown
- 2021-04-21 US US17/919,708 patent/US20230273110A1/en active Pending
- 2021-04-21 EP EP21725815.1A patent/EP4139686A1/en active Pending
- 2021-04-21 CA CA3175796A patent/CA3175796A1/en active Pending
- 2021-04-21 JP JP2022564132A patent/JP2023534780A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
MX2022012948A (es) | 2022-11-30 |
US20230273110A1 (en) | 2023-08-31 |
CA3175796A1 (en) | 2021-10-28 |
AU2021260997A1 (en) | 2022-12-22 |
KR20230026301A (ko) | 2023-02-24 |
IL297459A (en) | 2022-12-01 |
JP2023534780A (ja) | 2023-08-14 |
CN115698716A (zh) | 2023-02-03 |
WO2021214690A1 (en) | 2021-10-28 |
EP4139686A1 (en) | 2023-03-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CL2019002787A1 (es) | Método y sistema para la evaluación del aliento de un paciente para determinar la concentración de diversos. (divisional solicitud 201800570) | |
BR112022012883A2 (pt) | Instrumento cirúrgico compreendendo um sistema de detecção de orientação | |
BR102019009695B8 (pt) | Método realizado por um sistema de controle para uma máquina de trabalho, e, sistema de computação | |
CY1124765T1 (el) | Συστημα εντοπισμου εξαρτηματος εκπομπης και σχετικες μεθοδοι | |
MX2019003559A (es) | Deteccion de vulnerabilidades del servicio en un sistema de computacion distribuido. | |
BR112018006843A2 (pt) | sistema de fluxo e métodos para contagem digital | |
BR112019000108A2 (pt) | sistemas e métodos de dados de ar ópticos | |
BR112018071039A2 (pt) | método para desempenho de sistema de satélite de navegação global autônoma (gnss) aperfeiçoado | |
BR112014020015A8 (pt) | Citômetro de fluxo com microscópio digital holográfico | |
BR112016011052A2 (pt) | Sistema óptico e chip de análise para investigar, detectar e analisar moléculas | |
BR112013021381A2 (pt) | sistema e método para estabelecer uma rede de comunicações de incidente | |
BR112021024111A2 (pt) | Determinação de antidepressivos por espetrometria de massa | |
BR112014025384A8 (pt) | método e sistema para executar ensaio automatizado e métodos para executar teste reflexivo em vários exemplares | |
BR112013001556B8 (pt) | Método e sistema para analisar um pente de tiras de teste que tem uma pluralidade de dedos espaçado | |
BR112018012574A2 (pt) | métodos e aparelho para detecção de valores atípicos e correção de mapas de profundidade de luz estruturada | |
BR112019000490A2 (pt) | método de transmissão de dados, e dispositivo terminal | |
BR112019000742A2 (pt) | método e kit para analisar uma amostra | |
BR112017003103A8 (pt) | Método de estabelecer uma assinatura para uma entidade e sistema de provedor em nuvem | |
BR112019004990A2 (pt) | anticorpo que se liga especificamente a il-17a e fragmento funcional do mesmo | |
BR112015025691A2 (pt) | motor de regras analíticas para sistema de processamento de pagamento | |
BR112015015086A2 (pt) | calibração de válvula de fluido acústico | |
EA201990730A1 (ru) | Рнк-биомаркеры для наследственного ангионевротического отека | |
BR112017008507A2 (pt) | instrumento de validação de um sistema de monitoramento de um motor de aeronave | |
BR112014024648A8 (pt) | método e sistema para codificar por celp um sinal de áudio/voz e método de busca rápida de um livro-código mixado | |
BR112017000750A2 (pt) | gerenciamento de interferência em um ambiente de interferência intermitente |