BR112022019562A2 - Método e dispositivo para neuroestimulação, e, meio de armazenamento de memória - Google Patents

Método e dispositivo para neuroestimulação, e, meio de armazenamento de memória

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Publication number
BR112022019562A2
BR112022019562A2 BR112022019562A BR112022019562A BR112022019562A2 BR 112022019562 A2 BR112022019562 A2 BR 112022019562A2 BR 112022019562 A BR112022019562 A BR 112022019562A BR 112022019562 A BR112022019562 A BR 112022019562A BR 112022019562 A2 BR112022019562 A2 BR 112022019562A2
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BR
Brazil
Prior art keywords
brain region
neurostimulation
physiological activity
activity signal
storage media
Prior art date
Application number
BR112022019562A
Other languages
English (en)
Inventor
Zhu Weiran
Chen Lei
Ning Yihua
Original Assignee
Sceneray Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sceneray Co Ltd filed Critical Sceneray Co Ltd
Publication of BR112022019562A2 publication Critical patent/BR112022019562A2/pt

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36135—Control systems using physiological parameters
    • A61N1/36139—Control systems using physiological parameters with automatic adjustment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36067—Movement disorders, e.g. tremor or Parkinson disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/025—Digital circuitry features of electrotherapy devices, e.g. memory, clocks, processors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526—Head electrodes
    • A61N1/0529—Electrodes for brain stimulation
    • A61N1/0531—Brain cortex electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36082—Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease
    • A61N1/36089—Addiction or withdrawal from substance abuse such as alcohol or drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36082—Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease
    • A61N1/36096—Mood disorders, e.g. depression, anxiety or panic disorder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36132—Control systems using patient feedback
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N20/00—Machine learning
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/30—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to physical therapies or activities, e.g. physiotherapy, acupressure or exercising
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/70—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mental therapies, e.g. psychological therapy or autogenous training
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/67—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526—Head electrodes
    • A61N1/0529—Electrodes for brain stimulation
    • A61N1/0534—Electrodes for deep brain stimulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Radiology & Medical Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medical Informatics (AREA)
  • Developmental Disabilities (AREA)
  • Primary Health Care (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physiology (AREA)
  • Software Systems (AREA)
  • Theoretical Computer Science (AREA)
  • Addiction (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Data Mining & Analysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Physics & Mathematics (AREA)
  • Social Psychology (AREA)
  • Artificial Intelligence (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Evolutionary Computation (AREA)
  • Mathematical Physics (AREA)
  • Physics & Mathematics (AREA)
  • Computing Systems (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)

Abstract

MÉTODO E DISPOSITIVO PARA NEUROESTIMULAÇÃO, E, MEIO DE ARMAZENAMENTO DE MEMÓRIA. São providos um método e um dispositivo para neuroestimulação. O método para neuroestimulação inclui: detectar um sinal de atividade fisiológica de cada região cerebral na pelo menos uma região cerebral de um paciente por meio de um dispositivo de eletrodo implantável; comparar o sinal de atividade fisiológica detectado de cada região cerebral com uma condição de detecção predefinida para determinar se o sinal de atividade fisiológica detectado de cada região cerebral pertence a um sinal de atividade fisiológica anormal; e controlar se deve aplicar um sinal de estimulação elétrica a pelo menos uma região cerebral por meio do dispositivo de eletrodo implantável com base em um resultado de determinação do sinal de atividade fisiológica de cada região cerebral.
BR112022019562A 2020-03-30 2021-03-29 Método e dispositivo para neuroestimulação, e, meio de armazenamento de memória BR112022019562A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN202010236458.2A CN113457008A (zh) 2020-03-30 2020-03-30 用于对患者进行神经刺激的方法和装置
PCT/CN2021/083598 WO2021197267A1 (en) 2020-03-30 2021-03-29 Method and device for neuro-stimulation

Publications (1)

Publication Number Publication Date
BR112022019562A2 true BR112022019562A2 (pt) 2022-11-16

Family

ID=77855171

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022019562A BR112022019562A2 (pt) 2020-03-30 2021-03-29 Método e dispositivo para neuroestimulação, e, meio de armazenamento de memória

Country Status (5)

Country Link
US (1) US20210299452A1 (pt)
EP (1) EP4126200A4 (pt)
CN (1) CN113457008A (pt)
BR (1) BR112022019562A2 (pt)
WO (2) WO2021196652A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024023719A1 (en) * 2022-07-27 2024-02-01 Multi-Scale Medical Robotics Center Limited Wirelessly powered electrical stimulation systems and related methods
CN116942155A (zh) * 2023-09-21 2023-10-27 之江实验室 柔性植入式光电器件及其制备方法、控制方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050154612A1 (en) * 2004-01-09 2005-07-14 Steris Inc. Communication server for an instrument management system
US8600521B2 (en) * 2005-01-27 2013-12-03 Cyberonics, Inc. Implantable medical device having multiple electrode/sensor capability and stimulation based on sensed intrinsic activity
US7499752B2 (en) * 2005-07-29 2009-03-03 Cyberonics, Inc. Selective nerve stimulation for the treatment of eating disorders
US7391257B1 (en) * 2007-01-31 2008-06-24 Medtronic, Inc. Chopper-stabilized instrumentation amplifier for impedance measurement
WO2010048613A2 (en) * 2008-10-24 2010-04-29 The General Hospital Corporation System and method for dynamically configurable deep brain stimulation
EP2453977B1 (en) * 2009-07-15 2017-11-08 Cardiac Pacemakers, Inc. Physiological vibration detection in an implanted medical device
US8447406B2 (en) * 2010-06-29 2013-05-21 Medtronic, Inc. Medical method and device for monitoring a neural brain network
DE102015108861A1 (de) * 2015-06-03 2016-12-08 Cortec Gmbh Verfahren und Vorrichtung zur Neurostimulation
EP3618697A4 (en) * 2017-05-01 2021-03-03 HRL Laboratories, LLC LOW LATENCY AUTOMATED CLOSED LOOP SYNCHRONIZATION PROCESS OF NEUROSTIMULATION INTERVENTIONS ON NEUROPHYSIOLOGICAL ACTIVITY
CN107562191A (zh) * 2017-08-03 2018-01-09 天津大学 基于混合特征的精细想象动作在线脑‑机接口方法
US11154251B2 (en) * 2018-02-10 2021-10-26 The Governing Council Of The University Of Toronto System and method for classifying time series data for state identification
CN108606778B (zh) * 2018-04-16 2024-04-19 顾继炎 医疗装置、算法更新方法、医疗系统及外部监测装置
CA3130147A1 (en) * 2019-03-08 2020-09-17 Cala Health, Inc. Wearable peripheral nerve stimulation for the treatment of diseases utilizing rhythmic biological processes
GB2583789B (en) * 2019-09-19 2021-06-09 Bioinduction Ltd Apparatus for deep brain stimulation
US20210121697A1 (en) * 2019-10-23 2021-04-29 Medtronic, Inc. Multi-target adaptive neurostimulation therapy control
US20220062643A1 (en) * 2020-03-20 2022-03-03 Dirk De Ridder Neuromodulatory Method for Treating Neurological Disorders

Also Published As

Publication number Publication date
EP4126200A4 (en) 2023-10-04
WO2021197267A1 (en) 2021-10-07
EP4126200A1 (en) 2023-02-08
WO2021196652A1 (zh) 2021-10-07
US20210299452A1 (en) 2021-09-30
CN113457008A (zh) 2021-10-01

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