BR112022019380A2 - Receptores de células t - Google Patents
Receptores de células tInfo
- Publication number
- BR112022019380A2 BR112022019380A2 BR112022019380A BR112022019380A BR112022019380A2 BR 112022019380 A2 BR112022019380 A2 BR 112022019380A2 BR 112022019380 A BR112022019380 A BR 112022019380A BR 112022019380 A BR112022019380 A BR 112022019380A BR 112022019380 A2 BR112022019380 A2 BR 112022019380A2
- Authority
- BR
- Brazil
- Prior art keywords
- cell receptors
- polynucleotides
- polypeptides
- vectors
- cells
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Engineering & Computer Science (AREA)
- Virology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Rheumatology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063000800P | 2020-03-27 | 2020-03-27 | |
| PCT/US2021/024370 WO2021195503A1 (en) | 2020-03-27 | 2021-03-26 | T cell receptors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112022019380A2 true BR112022019380A2 (pt) | 2022-11-29 |
Family
ID=77890524
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112022019380A BR112022019380A2 (pt) | 2020-03-27 | 2021-03-26 | Receptores de células t |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20230124640A1 (https=) |
| EP (1) | EP4126924A4 (https=) |
| JP (2) | JP7738007B2 (https=) |
| KR (1) | KR20220160040A (https=) |
| CN (1) | CN115485294A (https=) |
| AU (1) | AU2021244594A1 (https=) |
| BR (1) | BR112022019380A2 (https=) |
| CA (1) | CA3177181A1 (https=) |
| IL (1) | IL296827A (https=) |
| MX (1) | MX2022012062A (https=) |
| WO (1) | WO2021195503A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3225252A1 (en) | 2021-07-14 | 2023-01-19 | Jordan JARJOUR | Engineered t cell receptors fused to binding domains from antibodies |
| CN119546328A (zh) | 2022-04-08 | 2025-02-28 | 再生元制药公司 | 多部分受体和信号传导复合物 |
| CN117003855B (zh) * | 2023-09-20 | 2024-02-23 | 广州市老人院 | 一种t细胞受体及其应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8361794B2 (en) * | 2004-06-29 | 2013-01-29 | Immunocore Limited | Cells expressing a modified T cell receptor |
| LT3424947T (lt) * | 2011-10-28 | 2021-03-10 | Regeneron Pharmaceuticals, Inc. | Genetiškai modifikuotos t ląstelių receptorių pelės |
| CN102876715B (zh) | 2012-09-05 | 2014-07-23 | 南方医科大学 | 一种用于结核/hiv共感染基因治疗的逆转录病毒载体及其应用 |
| CN102911267B (zh) | 2012-09-19 | 2014-04-02 | 南方医科大学 | 一种结核/hiv抗原肽双特异性tcr、其重组逆转录病毒载体与应用 |
| EP3472208B9 (en) | 2016-06-17 | 2023-10-04 | Medigene Immunotherapies GmbH | T cell receptors and uses thereof |
| CN110352068A (zh) * | 2016-12-02 | 2019-10-18 | 南加利福尼亚大学 | 合成的免疫受体及其使用方法 |
| BR112020006643A2 (pt) * | 2017-10-03 | 2020-09-24 | Juno Therapeutics Inc | moléculas de ligação específica ao hpv |
| EP3714941A1 (en) | 2019-03-27 | 2020-09-30 | Medigene Immunotherapies GmbH | Mage-a4 tcrs |
| KR20220030933A (ko) | 2019-05-08 | 2022-03-11 | 메디진 이뮤노테라피스 게엠바하 | 조작된 t 세포 |
| CA3225252A1 (en) * | 2021-07-14 | 2023-01-19 | Jordan JARJOUR | Engineered t cell receptors fused to binding domains from antibodies |
-
2021
- 2021-03-26 AU AU2021244594A patent/AU2021244594A1/en active Pending
- 2021-03-26 CN CN202180032592.3A patent/CN115485294A/zh active Pending
- 2021-03-26 MX MX2022012062A patent/MX2022012062A/es unknown
- 2021-03-26 EP EP21775262.5A patent/EP4126924A4/en active Pending
- 2021-03-26 CA CA3177181A patent/CA3177181A1/en active Pending
- 2021-03-26 IL IL296827A patent/IL296827A/en unknown
- 2021-03-26 US US17/914,483 patent/US20230124640A1/en active Pending
- 2021-03-26 WO PCT/US2021/024370 patent/WO2021195503A1/en not_active Ceased
- 2021-03-26 JP JP2022558271A patent/JP7738007B2/ja active Active
- 2021-03-26 KR KR1020227036819A patent/KR20220160040A/ko active Pending
- 2021-03-26 BR BR112022019380A patent/BR112022019380A2/pt unknown
-
2025
- 2025-09-01 JP JP2025144528A patent/JP2025172113A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR20220160040A (ko) | 2022-12-05 |
| IL296827A (en) | 2022-11-01 |
| CN115485294A (zh) | 2022-12-16 |
| CA3177181A1 (en) | 2021-09-30 |
| JP2025172113A (ja) | 2025-11-20 |
| EP4126924A1 (en) | 2023-02-08 |
| EP4126924A4 (en) | 2024-04-24 |
| JP7738007B2 (ja) | 2025-09-11 |
| JP2023519868A (ja) | 2023-05-15 |
| AU2021244594A1 (en) | 2022-12-01 |
| US20230124640A1 (en) | 2023-04-20 |
| MX2022012062A (es) | 2023-01-11 |
| WO2021195503A1 (en) | 2021-09-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B25A | Requested transfer of rights approved |
Owner name: REGENERON PHARMACEUTICALS, INC. (US) |