BR112022018136A2 - Composições e métodos para tratar lesões de reperfusão ou hemorragia após terapia de recanalização - Google Patents

Composições e métodos para tratar lesões de reperfusão ou hemorragia após terapia de recanalização

Info

Publication number
BR112022018136A2
BR112022018136A2 BR112022018136A BR112022018136A BR112022018136A2 BR 112022018136 A2 BR112022018136 A2 BR 112022018136A2 BR 112022018136 A BR112022018136 A BR 112022018136A BR 112022018136 A BR112022018136 A BR 112022018136A BR 112022018136 A2 BR112022018136 A2 BR 112022018136A2
Authority
BR
Brazil
Prior art keywords
methods
compositions
hemorrhage
thrombolytic drug
reperfusion injuries
Prior art date
Application number
BR112022018136A
Other languages
English (en)
Portuguese (pt)
Inventor
Joo Gwag Byoung
San An Chun
yu jin Jing
Ig Cho Sung
Zhu Fangmeng
Xu Xinliang
Zhan Weiqiang
Liu Fuxin
Won Soon-Mi
Original Assignee
Gnt Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gnt Pharma Co Ltd filed Critical Gnt Pharma Co Ltd
Publication of BR112022018136A2 publication Critical patent/BR112022018136A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
BR112022018136A 2020-03-11 2021-03-10 Composições e métodos para tratar lesões de reperfusão ou hemorragia após terapia de recanalização BR112022018136A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202062988187P 2020-03-11 2020-03-11
PCT/IB2021/000136 WO2021181159A1 (en) 2020-03-11 2021-03-10 Compositions and methods for treating reperfusion injury or hemorrhage after recanalization therapy

Publications (1)

Publication Number Publication Date
BR112022018136A2 true BR112022018136A2 (pt) 2022-10-25

Family

ID=77665492

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022018136A BR112022018136A2 (pt) 2020-03-11 2021-03-10 Composições e métodos para tratar lesões de reperfusão ou hemorragia após terapia de recanalização

Country Status (12)

Country Link
US (3) US11826329B2 (https=)
EP (1) EP4117648A4 (https=)
JP (1) JP2023517566A (https=)
KR (1) KR20230010187A (https=)
CN (1) CN115515573A (https=)
AU (1) AU2021233206A1 (https=)
BR (1) BR112022018136A2 (https=)
CA (1) CA3174709A1 (https=)
CO (1) CO2022014343A2 (https=)
IL (2) IL309923A (https=)
MX (2) MX2022011214A (https=)
WO (1) WO2021181159A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12285182B2 (en) 2018-10-10 2025-04-29 Innova Vascular, Inc. Devices and methods for removing an embolus
CN115515573A (zh) 2020-03-11 2022-12-23 Gnt制药有限公司 用于治疗再通疗法之后再灌注损伤或出血的组合物和方法
CN113995723B (zh) 2020-07-27 2025-02-18 浙江普洛家园药业有限公司 一种索法地尔冻干粉针剂的制备方法及其产品和用途
JP2025500716A (ja) * 2021-12-28 2025-01-14 ジーエヌティー ファーマ カンパニー， リミテッド 肺障害を処置するための組成物及び方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1551793B1 (en) * 2002-06-19 2016-01-20 AmKor Pharma, Inc. Tetrafluorobenzyl derivatives and pharmaceutical composition for preventing and treating acute and chronic neurodegenerative diseases in central nervous system containing the same
KR100522188B1 (ko) * 2003-01-20 2005-10-18 주식회사 뉴로테크 뉴로트로핀에 의해 유도되는 세포괴사 억제 방법
WO2006126825A1 (en) 2005-05-23 2006-11-30 Choongwae Pharma Corporation Composition comprising tetrafluorobenzyl derivatives or salts of thereof for injection
EP1883619B8 (en) * 2005-05-25 2013-05-01 JW Pharmaceutical Corporation Process of preparation of substituted tetrafluorobenzylaniline compound and its pharmaceutically approved salts
KR101523345B1 (ko) * 2008-04-28 2015-05-28 주식회사 지엔티파마 재관류 손상의 치료 또는 예방용 약학 조성물
CN102617383A (zh) 2012-03-20 2012-08-01 横店集团家园化工有限公司 索法地尔晶型、制备方法及包含索法地尔晶体的无菌粉末
AU2016210973B2 (en) 2015-01-27 2019-02-14 Astrazeneca Ab Method of treating or prevention of atherothrombotic events in patients with history of myocardial infarction
CN115515573A (zh) 2020-03-11 2022-12-23 Gnt制药有限公司 用于治疗再通疗法之后再灌注损伤或出血的组合物和方法

Also Published As

Publication number Publication date
WO2021181159A1 (en) 2021-09-16
CA3174709A1 (en) 2021-09-16
EP4117648A4 (en) 2024-05-29
EP4117648A1 (en) 2023-01-18
IL296288B2 (en) 2024-06-01
KR20230010187A (ko) 2023-01-18
IL296288A (en) 2022-11-01
US11826329B2 (en) 2023-11-28
US20260027076A1 (en) 2026-01-29
CN115515573A (zh) 2022-12-23
IL296288B1 (en) 2024-02-01
US20230390231A1 (en) 2023-12-07
CO2022014343A2 (es) 2023-02-16
JP2023517566A (ja) 2023-04-26
IL309923A (en) 2024-03-01
AU2021233206A1 (en) 2022-10-06
MX2025012439A (es) 2025-11-03
MX2022011214A (es) 2022-10-07
US12433861B2 (en) 2025-10-07
US20210283080A1 (en) 2021-09-16

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Legal Events

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B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]
B154 Notification of filing of divisional application [chapter 15.50 patent gazette]

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