BR112022017163A2 - Método e sistema para medir pelo menos uma propriedade biomecânica de uma estrutura celular reprodutiva - Google Patents
Método e sistema para medir pelo menos uma propriedade biomecânica de uma estrutura celular reprodutivaInfo
- Publication number
- BR112022017163A2 BR112022017163A2 BR112022017163A BR112022017163A BR112022017163A2 BR 112022017163 A2 BR112022017163 A2 BR 112022017163A2 BR 112022017163 A BR112022017163 A BR 112022017163A BR 112022017163 A BR112022017163 A BR 112022017163A BR 112022017163 A2 BR112022017163 A2 BR 112022017163A2
- Authority
- BR
- Brazil
- Prior art keywords
- cell structure
- reproductive cell
- biomechanical property
- measuring
- reproductive
- Prior art date
Links
- 210000005132 reproductive cell Anatomy 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 5
- 230000005855 radiation Effects 0.000 abstract 3
- 238000001228 spectrum Methods 0.000 abstract 2
- 230000035899 viability Effects 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/1702—Systems in which incident light is modified in accordance with the properties of the material investigated with opto-acoustic detection, e.g. for gases or analysing solids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/4833—Physical analysis of biological material of solid biological material, e.g. tissue samples, cell cultures
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/43—Detecting, measuring or recording for evaluating the reproductive systems
- A61B5/4306—Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
- A61B5/4343—Pregnancy and labour monitoring, e.g. for labour onset detection
- A61B5/4362—Assessing foetal parameters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/636—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited using an arrangement of pump beam and probe beam; using the measurement of optical non-linear properties
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5026—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on cell morphology
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5029—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on cell motility
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
- G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F17/00—Digital computing or data processing equipment or methods, specially adapted for specific functions
- G06F17/10—Complex mathematical operations
- G06F17/18—Complex mathematical operations for evaluating statistical data, e.g. average values, frequency distributions, probability functions, regression analysis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2503/00—Evaluating a particular growth phase or type of persons or animals
- A61B2503/02—Foetus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2503/00—Evaluating a particular growth phase or type of persons or animals
- A61B2503/42—Evaluating a particular growth phase or type of persons or animals for laboratory research
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/636—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited using an arrangement of pump beam and probe beam; using the measurement of optical non-linear properties
- G01N2021/638—Brillouin effect, e.g. stimulated Brillouin effect
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Surgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Optics & Photonics (AREA)
- Animal Behavior & Ethology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Data Mining & Analysis (AREA)
- Physiology (AREA)
- Pediatric Medicine (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Theoretical Computer Science (AREA)
- Pure & Applied Mathematics (AREA)
Abstract
MÉTODO E SISTEMA PARA MEDIR PELO MENOS UMA PROPRIEDADE BIOMECÂNICA DE UMA ESTRUTURA CELULAR REPRODUTIVA. Um método para medir pelo menos uma propriedade biomecânica de uma estrutura celular reprodutiva é fornecido. O método inclui iluminar a estrutura celular reprodutiva com radiação; detectar pelo menos uma porção de radiação espalhada da estrutura celular reprodutiva iluminada; analisar um espectro de frequência da radiação espalhada detectada para identificar pelo menos uma mudança de frequência de Brillouin no espectro de frequência; e determinar a pelo menos uma propriedade biomecânica com base na mudança de frequência de Brillouin. O método inclui ainda determinar um índice de viabilidade da estrutura celular reprodutiva com base na pelo menos uma propriedade biomecânica.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202062982368P | 2020-02-27 | 2020-02-27 | |
PCT/US2021/020312 WO2021174207A1 (en) | 2020-02-27 | 2021-03-01 | Contactless inspection of reproductive cellular structures using optical measurement of biomechanical properties |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112022017163A2 true BR112022017163A2 (pt) | 2022-11-08 |
Family
ID=77463651
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112022017163A BR112022017163A2 (pt) | 2020-02-27 | 2021-03-01 | Método e sistema para medir pelo menos uma propriedade biomecânica de uma estrutura celular reprodutiva |
Country Status (10)
Country | Link |
---|---|
US (1) | US20210270810A1 (pt) |
EP (1) | EP4111192A4 (pt) |
JP (1) | JP2023516591A (pt) |
KR (1) | KR20230004460A (pt) |
CN (1) | CN115552243A (pt) |
AU (1) | AU2021228781A1 (pt) |
BR (1) | BR112022017163A2 (pt) |
CA (1) | CA3169330A1 (pt) |
GB (1) | GB2607785A (pt) |
WO (1) | WO2021174207A1 (pt) |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2013138513A1 (en) * | 2012-03-13 | 2013-09-19 | The Regents Of The University Of California | Application of light scattering patterns to determine differentiation status of stem cells and stem cell colonies |
KR20150107774A (ko) * | 2013-01-08 | 2015-09-23 | 더 브리검 앤드 우먼즈 하스피털, 인크. | 난모세포 및 배아의 평가를 위한 대사 이미징 방법 |
ES2928476T3 (es) * | 2015-09-02 | 2022-11-18 | Massachusetts Gen Hospital | Realización de un procedimiento basándose en propiedades monitorizadas de tejidos biológicos |
EP3394939A4 (en) * | 2015-12-22 | 2019-08-07 | Canon U.S. Life Sciences, Inc. | SYSTEM AND METHOD FOR MARKER-FREE CYTOMETRY BASED ON BRILLOUIN DIFFUSION |
WO2019089531A1 (en) * | 2017-10-30 | 2019-05-09 | University Of Maryland, College Park | Brillouin imaging devices, and systems and methods employing such devices |
-
2021
- 2021-03-01 CA CA3169330A patent/CA3169330A1/en active Pending
- 2021-03-01 WO PCT/US2021/020312 patent/WO2021174207A1/en unknown
- 2021-03-01 BR BR112022017163A patent/BR112022017163A2/pt unknown
- 2021-03-01 EP EP21759543.8A patent/EP4111192A4/en active Pending
- 2021-03-01 KR KR1020227033510A patent/KR20230004460A/ko not_active Application Discontinuation
- 2021-03-01 JP JP2022550895A patent/JP2023516591A/ja active Pending
- 2021-03-01 CN CN202180031412.XA patent/CN115552243A/zh active Pending
- 2021-03-01 AU AU2021228781A patent/AU2021228781A1/en active Pending
- 2021-03-01 US US17/188,972 patent/US20210270810A1/en active Pending
- 2021-03-01 GB GB2212265.9A patent/GB2607785A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
GB202212265D0 (en) | 2022-10-05 |
EP4111192A4 (en) | 2024-03-20 |
WO2021174207A1 (en) | 2021-09-02 |
CN115552243A (zh) | 2022-12-30 |
CA3169330A1 (en) | 2021-09-02 |
EP4111192A1 (en) | 2023-01-04 |
JP2023516591A (ja) | 2023-04-20 |
KR20230004460A (ko) | 2023-01-06 |
AU2021228781A1 (en) | 2022-09-22 |
GB2607785A (en) | 2022-12-14 |
US20210270810A1 (en) | 2021-09-02 |
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