BR112022008095A2 - Métodos e composições para o tratamento da síndrome de rett - Google Patents
Métodos e composições para o tratamento da síndrome de rettInfo
- Publication number
- BR112022008095A2 BR112022008095A2 BR112022008095A BR112022008095A BR112022008095A2 BR 112022008095 A2 BR112022008095 A2 BR 112022008095A2 BR 112022008095 A BR112022008095 A BR 112022008095A BR 112022008095 A BR112022008095 A BR 112022008095A BR 112022008095 A2 BR112022008095 A2 BR 112022008095A2
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- compositions
- treatment
- rett syndrome
- syndrome
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Psychiatry (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Hospice & Palliative Care (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Detergent Compositions (AREA)
- Chemical Or Physical Treatment Of Fibers (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962927008P | 2019-10-28 | 2019-10-28 | |
| US202063031201P | 2020-05-28 | 2020-05-28 | |
| PCT/US2020/057627 WO2021086892A1 (en) | 2019-10-28 | 2020-10-28 | Methods and compositions for treatment of rett syndrome |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112022008095A2 true BR112022008095A2 (pt) | 2022-07-12 |
Family
ID=75715568
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112022008095A BR112022008095A2 (pt) | 2019-10-28 | 2020-10-28 | Métodos e composições para o tratamento da síndrome de rett |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20220339138A1 (https=) |
| EP (1) | EP4051308A4 (https=) |
| JP (2) | JP2022553888A (https=) |
| KR (1) | KR20220106982A (https=) |
| CN (1) | CN115335071A (https=) |
| AU (1) | AU2020376801A1 (https=) |
| BR (1) | BR112022008095A2 (https=) |
| CA (1) | CA3156680A1 (https=) |
| CL (1) | CL2022001079A1 (https=) |
| CO (1) | CO2022007501A2 (https=) |
| IL (1) | IL292617B2 (https=) |
| MX (1) | MX2022004785A (https=) |
| TW (1) | TW202116300A (https=) |
| WO (1) | WO2021086892A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL310045A (en) | 2021-07-12 | 2024-03-01 | Acadia Pharm Inc | Crystalline forms of tropintide |
| WO2023242844A1 (en) * | 2022-06-15 | 2023-12-21 | Ramot At Tel-Aviv University Ltd. | Method and therapeutic agent for treatment of disease or disorder associated with impaired firing rate and/or mitochondrial calcium homeostasis |
| WO2025262646A1 (en) * | 2024-06-22 | 2025-12-26 | Biophore India Pharmaceuticals Pvt. Ltd | Dosage forms of trofinetide and its pharmaceutically acceptable salt thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6709817B1 (en) * | 1999-09-07 | 2004-03-23 | Baylor College Of Medicine | Method of screening Rett syndrome by detecting a mutation in MECP2 |
| US9708366B2 (en) * | 2011-01-27 | 2017-07-18 | Neuren Pharmaceuticals Ltd. | Treatment of fragile X syndrome using glycyl-L-2-methylprolyl-L-glutamate |
| WO2014130691A2 (en) * | 2013-02-20 | 2014-08-28 | Theravasc Inc. | Pharmaceutical formulations of nitrite and uses thereof |
| WO2015013397A2 (en) * | 2013-07-25 | 2015-01-29 | Neuren Pharmaceuticals Limited | Neuroprotective bicyclic compounds and methods for their use in treating autism spectrum disorders and neurodevelopmental disorders |
| US20150224164A1 (en) * | 2013-11-26 | 2015-08-13 | Neuren Pharmaceuticals Limited | Treatment of autism spectrum disorders using glycyl-l-2-methylprolyl-l-glumatic acid |
| GB2554064B (en) * | 2016-09-01 | 2019-11-20 | Jit Singh Shailinder | An enteral feeding tube |
-
2020
- 2020-10-28 BR BR112022008095A patent/BR112022008095A2/pt unknown
- 2020-10-28 JP JP2022552123A patent/JP2022553888A/ja active Pending
- 2020-10-28 WO PCT/US2020/057627 patent/WO2021086892A1/en not_active Ceased
- 2020-10-28 IL IL292617A patent/IL292617B2/en unknown
- 2020-10-28 EP EP20883589.2A patent/EP4051308A4/en active Pending
- 2020-10-28 AU AU2020376801A patent/AU2020376801A1/en active Pending
- 2020-10-28 MX MX2022004785A patent/MX2022004785A/es unknown
- 2020-10-28 CN CN202080090500.2A patent/CN115335071A/zh active Pending
- 2020-10-28 CA CA3156680A patent/CA3156680A1/en active Pending
- 2020-10-28 TW TW109137417A patent/TW202116300A/zh unknown
- 2020-10-28 KR KR1020227018117A patent/KR20220106982A/ko active Pending
-
2022
- 2022-02-01 US US17/590,496 patent/US20220339138A1/en active Pending
- 2022-04-28 CL CL2022001079A patent/CL2022001079A1/es unknown
- 2022-05-31 CO CONC2022/0007501A patent/CO2022007501A2/es unknown
-
2025
- 2025-07-10 JP JP2025116586A patent/JP2025148461A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN115335071A (zh) | 2022-11-11 |
| TW202116300A (zh) | 2021-05-01 |
| CA3156680A1 (en) | 2021-05-06 |
| CL2022001079A1 (es) | 2023-04-21 |
| EP4051308A4 (en) | 2023-08-23 |
| MX2022004785A (es) | 2022-05-16 |
| CO2022007501A2 (es) | 2022-08-30 |
| KR20220106982A (ko) | 2022-08-01 |
| US20220339138A1 (en) | 2022-10-27 |
| AU2020376801A1 (en) | 2022-06-09 |
| IL292617B1 (en) | 2025-11-01 |
| IL292617B2 (en) | 2026-03-01 |
| EP4051308A1 (en) | 2022-09-07 |
| WO2021086892A1 (en) | 2021-05-06 |
| IL292617A (en) | 2022-07-01 |
| JP2025148461A (ja) | 2025-10-07 |
| JP2022553888A (ja) | 2022-12-26 |
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