BR112022007926A2 - Composições de cocktail que compreendem fagos antibacterianos respiratórios e métodos de utilização das mesmas - Google Patents

Composições de cocktail que compreendem fagos antibacterianos respiratórios e métodos de utilização das mesmas

Info

Publication number
BR112022007926A2
BR112022007926A2 BR112022007926A BR112022007926A BR112022007926A2 BR 112022007926 A2 BR112022007926 A2 BR 112022007926A2 BR 112022007926 A BR112022007926 A BR 112022007926A BR 112022007926 A BR112022007926 A BR 112022007926A BR 112022007926 A2 BR112022007926 A2 BR 112022007926A2
Authority
BR
Brazil
Prior art keywords
methods
including respiratory
compositions including
infections
bacterial
Prior art date
Application number
BR112022007926A
Other languages
English (en)
Inventor
Isabel Rodrigues Leandro Clara
Raquel Martins Barbosa Ana
Jones Dias Daniela
Filipa Martins Ana
Ângelo Da Costa Garcia Miguel
Volker Côrte-Real Sofia
Original Assignee
Technophage Investig E Desenvolvimento Em Biotecnologia Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Technophage Investig E Desenvolvimento Em Biotecnologia Sa filed Critical Technophage Investig E Desenvolvimento Em Biotecnologia Sa
Publication of BR112022007926A2 publication Critical patent/BR112022007926A2/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/40—Viruses, e.g. bacteriophages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10111—Myoviridae
    • C12N2795/10121—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10111—Myoviridae
    • C12N2795/10132—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/26—Infectious diseases, e.g. generalised sepsis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Toxicology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)

Abstract

A presente invenção dirige-se ao campo da terapia de fagos para o tratamento e controlo de infeções bacterianas, em particular infeções bacterianas respiratórias tais como pneumonia bacteriana. Mais especificamente, a presente invenção dirige-se a novas estirpes de bacteriófagos e cocktails das mesmas, assim como variantes das mesmas; e métodos de utilização das mesmas no tratamento e prevenção de infeções bacterianas, incluindo infeções respiratórias causadas por, por exemplo, Pseudomonas aeruginosa e/ou Klebsiella pneumoniae. Os cocktails são utilizados como composições farmacêuticas, quer sejam sozinhos ou em combinação adicional com outras terapias, por exemplo, antibióticos ou outras terapias padrão e não padrão para infeções respiratórias.
BR112022007926A 2019-12-19 2020-12-21 Composições de cocktail que compreendem fagos antibacterianos respiratórios e métodos de utilização das mesmas BR112022007926A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962950850P 2019-12-19 2019-12-19
PCT/PT2020/050058 WO2021125988A1 (en) 2019-12-19 2020-12-21 Cocktail compositions comprising respiratory antibacterial phages and methods of use thereof

Publications (1)

Publication Number Publication Date
BR112022007926A2 true BR112022007926A2 (pt) 2022-07-12

Family

ID=74554200

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022007926A BR112022007926A2 (pt) 2019-12-19 2020-12-21 Composições de cocktail que compreendem fagos antibacterianos respiratórios e métodos de utilização das mesmas

Country Status (8)

Country Link
US (1) US20210187046A1 (pt)
EP (1) EP4075984A1 (pt)
JP (1) JP2023507080A (pt)
CN (1) CN114929868A (pt)
AU (1) AU2020407755A1 (pt)
BR (1) BR112022007926A2 (pt)
CA (1) CA3157249A1 (pt)
WO (1) WO2021125988A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113025582B (zh) * 2021-05-19 2022-04-15 吉林大学 一株肺炎克雷伯菌噬菌体及医用用途
EP4265263A1 (en) * 2022-04-19 2023-10-25 Fundacion Instituto De Investigacion Sanitaria Fundacion Jimenez Diaz Bacteriophage suitable for treating a bacterial infection caused by pseudomonas aeruginosa
EP4265264A1 (en) * 2022-04-19 2023-10-25 Fundacion Instituto De Investigacion Sanitaria Fundacion Jimenez Diaz Bacteriophages suitable for treating a bacterial infection caused by klebsiella pneumoniae

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI1008663B8 (pt) 2009-02-06 2021-10-05 Technophage Investig E Desenvolvimento Em Biotecnologia S A bacteriófago com um genoma, composição farmacêutica, uso de uma quantidade terapeuticamente eficaz da composição farmacêutica, método de diagnóstico do agente causador de uma infecção bacteriana e uso do bacteriófago
EP3789031B1 (en) 2010-09-17 2023-08-02 Technophage, Investigação e Desenvolvimento em Biotecnologia, SA Antibacterial phage, phage peptides and methods of use thereof
ES2912268T3 (es) * 2016-12-05 2022-05-25 Technophage Investig E Desenvolvimento Em Biotecnologia Sa Composiciones de bacteriófagos que comprenden fagos antibacterianos respiratorios y procedimientos de uso de las mismas

Also Published As

Publication number Publication date
US20210187046A1 (en) 2021-06-24
CA3157249A1 (en) 2021-06-24
AU2020407755A1 (en) 2022-05-19
CN114929868A (zh) 2022-08-19
EP4075984A1 (en) 2022-10-26
WO2021125988A1 (en) 2021-06-24
JP2023507080A (ja) 2023-02-21

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