BR112022007094A2 - Compostos de carboxilato heterocíclicos como inibidores de glicolato oxidase - Google Patents

Compostos de carboxilato heterocíclicos como inibidores de glicolato oxidase

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Publication number
BR112022007094A2
BR112022007094A2 BR112022007094A BR112022007094A BR112022007094A2 BR 112022007094 A2 BR112022007094 A2 BR 112022007094A2 BR 112022007094 A BR112022007094 A BR 112022007094A BR 112022007094 A BR112022007094 A BR 112022007094A BR 112022007094 A2 BR112022007094 A2 BR 112022007094A2
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BR
Brazil
Prior art keywords
glycolate oxidase
oxidase inhibitors
carboxylate compounds
heterocyclic carboxylate
heterocyclic
Prior art date
Application number
BR112022007094A
Other languages
English (en)
Inventor
A Codelli Julian
C Desai Manoj
Guo Hongyan
S Lee Amy
W Mitra Aurpon
Pyun Hyung-Jung
M Shivakumar Devleena
Xu Lianhong
E Knox John
Original Assignee
Gyanrx Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gyanrx Sciences Inc filed Critical Gyanrx Sciences Inc
Publication of BR112022007094A2 publication Critical patent/BR112022007094A2/pt

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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • C07D249/06—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles with aryl radicals directly attached to ring atoms
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    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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Abstract

COMPOSTOS DE CARBOXILATO HETEROCÍCLICOS COMO INIBIDORES DE GLICOLATO OXIDASE. A presente invenção refere-se genericamente aos moduladores da enzima glicolato oxidase humana e métodos de uso e fabricação dos mesmos.
BR112022007094A 2019-11-01 2020-10-27 Compostos de carboxilato heterocíclicos como inibidores de glicolato oxidase BR112022007094A2 (pt)

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