BR112022005938A2 - Carboxamidas indazol como inibidores de quinase - Google Patents
Carboxamidas indazol como inibidores de quinaseInfo
- Publication number
- BR112022005938A2 BR112022005938A2 BR112022005938A BR112022005938A BR112022005938A2 BR 112022005938 A2 BR112022005938 A2 BR 112022005938A2 BR 112022005938 A BR112022005938 A BR 112022005938A BR 112022005938 A BR112022005938 A BR 112022005938A BR 112022005938 A2 BR112022005938 A2 BR 112022005938A2
- Authority
- BR
- Brazil
- Prior art keywords
- kinase inhibitors
- indazole carboxamides
- carboxamides
- indazole
- kinase
- Prior art date
Links
- -1 INDAZOLE CARBOXAMIDES Chemical class 0.000 title abstract 2
- 229940043355 kinase inhibitor Drugs 0.000 title abstract 2
- 239000003757 phosphotransferase inhibitor Substances 0.000 title abstract 2
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 101001109145 Homo sapiens Receptor-interacting serine/threonine-protein kinase 1 Proteins 0.000 abstract 1
- 108091000080 Phosphotransferase Proteins 0.000 abstract 1
- 102100022501 Receptor-interacting serine/threonine-protein kinase 1 Human genes 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 102000020233 phosphotransferase Human genes 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
CARBOXAMIDAS INDAZOL COMO INIBIDORES DE QUINASE. A presente invenção refere-se a compostos tendo fórmula (I), e enantiômeros, e diastereômeros, estereoisômeros, farmaceuticamente aceitáveis sais do mesmo, são úteis como moduladores de quinase, incluindo a modulação de RIPK1. Todas as variáveis são como aqui definidas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962909920P | 2019-10-03 | 2019-10-03 | |
| US2021067654 | 2021-04-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112022005938A2 true BR112022005938A2 (pt) | 2022-06-28 |
Family
ID=83355870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112022005938A BR112022005938A2 (pt) | 2019-10-03 | 2020-10-02 | Carboxamidas indazol como inibidores de quinase |
Country Status (1)
| Country | Link |
|---|---|
| BR (1) | BR112022005938A2 (pt) |
-
2020
- 2020-10-02 BR BR112022005938A patent/BR112022005938A2/pt not_active Application Discontinuation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |