BR112022003670A2 - Métodos de tratamento - Google Patents
Métodos de tratamentoInfo
- Publication number
- BR112022003670A2 BR112022003670A2 BR112022003670A BR112022003670A BR112022003670A2 BR 112022003670 A2 BR112022003670 A2 BR 112022003670A2 BR 112022003670 A BR112022003670 A BR 112022003670A BR 112022003670 A BR112022003670 A BR 112022003670A BR 112022003670 A2 BR112022003670 A2 BR 112022003670A2
- Authority
- BR
- Brazil
- Prior art keywords
- treatment
- treatment methods
- tumors
- pde1
- certain cancers
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/005—Enzyme inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
métodos de tratamento. a divulgação refere-se à combinação de inibidores de fosfodiesterase 1 (pde1) úteis para o tratamento de certos cânceres ou tumores, tais como câncer de cólon. em outra forma de realização, a divulgação refere-se ao uso de inibidores de pde1 e um agente antitumoral opcional para o tratamento de certos cânceres ou tumores.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962895476P | 2019-09-03 | 2019-09-03 | |
PCT/US2020/049248 WO2021046250A1 (en) | 2019-09-03 | 2020-09-03 | Methods of treatment |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112022003670A2 true BR112022003670A2 (pt) | 2022-05-24 |
Family
ID=74853030
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112022003670A BR112022003670A2 (pt) | 2019-09-03 | 2020-09-03 | Métodos de tratamento |
Country Status (11)
Country | Link |
---|---|
US (1) | US20220354851A1 (pt) |
EP (1) | EP4025218A4 (pt) |
JP (1) | JP2022546711A (pt) |
KR (1) | KR20220054853A (pt) |
CN (1) | CN114340636A (pt) |
AU (1) | AU2020343329A1 (pt) |
BR (1) | BR112022003670A2 (pt) |
CA (1) | CA3147071A1 (pt) |
IL (1) | IL290983A (pt) |
MX (1) | MX2022002607A (pt) |
WO (1) | WO2021046250A1 (pt) |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3157926B1 (en) * | 2014-06-20 | 2019-05-15 | Intra-Cellular Therapies, Inc. | Organic compounds |
IL260933B2 (en) * | 2016-02-08 | 2023-04-01 | Beyondspring Pharmaceuticals Inc | Preparations containing tocorsol or its analogues |
SG11202001664VA (en) * | 2017-08-31 | 2020-03-30 | Abbvie Inc | Ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1) inhibitors and uses thereof |
US20220072003A1 (en) * | 2019-01-07 | 2022-03-10 | Intra-Cellular Therapies, Inc. | Organic compounds |
-
2020
- 2020-09-03 US US17/640,050 patent/US20220354851A1/en active Pending
- 2020-09-03 CN CN202080062144.3A patent/CN114340636A/zh active Pending
- 2020-09-03 BR BR112022003670A patent/BR112022003670A2/pt unknown
- 2020-09-03 AU AU2020343329A patent/AU2020343329A1/en active Pending
- 2020-09-03 CA CA3147071A patent/CA3147071A1/en active Pending
- 2020-09-03 JP JP2022514215A patent/JP2022546711A/ja active Pending
- 2020-09-03 KR KR1020227010604A patent/KR20220054853A/ko unknown
- 2020-09-03 MX MX2022002607A patent/MX2022002607A/es unknown
- 2020-09-03 EP EP20860677.2A patent/EP4025218A4/en active Pending
- 2020-09-03 WO PCT/US2020/049248 patent/WO2021046250A1/en active Application Filing
-
2022
- 2022-02-28 IL IL290983A patent/IL290983A/en unknown
Also Published As
Publication number | Publication date |
---|---|
CA3147071A1 (en) | 2021-03-11 |
EP4025218A4 (en) | 2023-05-31 |
KR20220054853A (ko) | 2022-05-03 |
IL290983A (en) | 2022-05-01 |
CN114340636A (zh) | 2022-04-12 |
JP2022546711A (ja) | 2022-11-07 |
EP4025218A1 (en) | 2022-07-13 |
AU2020343329A1 (en) | 2022-03-24 |
WO2021046250A1 (en) | 2021-03-11 |
US20220354851A1 (en) | 2022-11-10 |
MX2022002607A (es) | 2022-03-25 |
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