BR112021024633A2 - Composições e métodos que usam trigonelina e vitaminas para evitar ou tratar condições ou distúrbios no músculo esquelético - Google Patents

Composições e métodos que usam trigonelina e vitaminas para evitar ou tratar condições ou distúrbios no músculo esquelético

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Publication number
BR112021024633A2
BR112021024633A2 BR112021024633A BR112021024633A BR112021024633A2 BR 112021024633 A2 BR112021024633 A2 BR 112021024633A2 BR 112021024633 A BR112021024633 A BR 112021024633A BR 112021024633 A BR112021024633 A BR 112021024633A BR 112021024633 A2 BR112021024633 A2 BR 112021024633A2
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BR
Brazil
Prior art keywords
compositions
methods
skeletal muscle
prevent
vitamins
Prior art date
Application number
BR112021024633A
Other languages
English (en)
Inventor
Jerome Feige
Pilar Giner Maria
Mathieu Membrez
Sofia Moco
Stefan Christen
Vincenzo Sorrentino
Original Assignee
Nestle Sa
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Filing date
Publication date
Application filed by Nestle Sa filed Critical Nestle Sa
Publication of BR112021024633A2 publication Critical patent/BR112021024633A2/pt

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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4425—Pyridinium derivatives, e.g. pralidoxime, pyridostigmine
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4415—Pyridoxine, i.e. Vitamin B6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
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    • A61K31/592—9,10-Secoergostane derivatives, e.g. ergocalciferol, i.e. vitamin D2
    • A—HUMAN NECESSITIES
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    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135—Compounds containing heavy metals
    • A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
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    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
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    • A61P21/06—Anabolic agents
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
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Abstract

composições e métodos que usam trigonlina e vitaminas para evitar ou tratar condições ou distúrbios no músculo esquelético. a presente invenção refere-se a composições e métodos para evitar ou tratar condições ou doenças do músculo esquelético. a presente invenção também se refere a composições e métodos que ajudam a aumentar os níveis de nad+ no músculo esquelético. de preferência, a presente invenção refere-se a composições e métodos que usam trigonelina e vitaminas selecionadas do grupo que consiste em: vitamina d, vitamina b12, b3, b6, b7, vitamina c e/ou vitamina e, para prevenir ou tratar doenças ou condições do músculo esquelético. o receptor das composições da invenção pode ser, por exemplo, um indivíduo idoso ou um indivíduo com sarcopenia, ou um indivíduo que necessite das composições e métodos da invenção para recuperação de músculos esqueléticos, por exemplo, após exercício, lesão muscular ou cirurgia.
BR112021024633A 2019-07-05 2020-07-03 Composições e métodos que usam trigonelina e vitaminas para evitar ou tratar condições ou distúrbios no músculo esquelético BR112021024633A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP19184820 2019-07-05
PCT/EP2020/068781 WO2021004919A1 (en) 2019-07-05 2020-07-03 Compositions and methods using trigonelline and vitamins for preventing or treating conditions or disorders in skeletal muscle

Publications (1)

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BR112021024633A2 true BR112021024633A2 (pt) 2022-01-18

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US (1) US20220241259A1 (pt)
EP (1) EP3993791A1 (pt)
JP (1) JP2022538154A (pt)
CN (1) CN113993546A (pt)
AU (1) AU2020310496A1 (pt)
BR (1) BR112021024633A2 (pt)
CA (1) CA3140735A1 (pt)
WO (1) WO2021004919A1 (pt)

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WO2022090456A1 (en) * 2020-10-30 2022-05-05 Société des Produits Nestlé S.A. Compositions containing nicotinamide and vitamin b6 and methods of using such compositions for rehabilitation
US20230390263A1 (en) * 2020-10-30 2023-12-07 Societe Des Produits Nestle S.A. Compositions containing nicotinamide and vitamin b6 and methods of using such compositions for treating cachexia or precachexia
JP2023547038A (ja) * 2020-10-30 2023-11-09 ソシエテ・デ・プロデュイ・ネスレ・エス・アー ニコチンアミド及びビタミンｂ６を含有する組成物、並びにサルコペニア及び虚弱を治療するためにかかる組成物を使用する方法
WO2024068808A1 (en) * 2022-09-30 2024-04-04 Société des Produits Nestlé S.A. Composition and method for treating muscle decline associated with renal disease or dysfunction

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DE3603601C3 (de) * 1986-02-06 1999-12-23 Jutta Mai Verwendung eines Bockshornkleesamenextraktes
DE3808141A1 (de) * 1988-03-11 1989-09-21 Mai Jutta Mittel zur bekaempfung von migraene
US5133958A (en) * 1989-04-20 1992-07-28 Erwin Stuckler Agent for nail, skin and hair care
DE202005021598U1 (de) * 2005-12-01 2008-12-04 Icb Investment Consulting Und Beteiligungen Gmbh Dermatologische Formulierung
EP2440206B1 (en) * 2009-06-11 2018-07-18 DSM IP Assets B.V. Trigonellin as a muscle stimulant
EP2382868A1 (en) * 2010-04-30 2011-11-02 Tchibo GmbH Healthy coffee and method of its production
EP2986158A1 (en) * 2013-03-15 2016-02-24 Abbott Laboratories Methods of maintaining and improving muscle function
US9855308B2 (en) * 2014-09-19 2018-01-02 Akay Flavours & Aromatics Pvt. Ltd. Composition for amelioration of peri- and post-menopausal symptoms and a process for producing the same
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EP3711493A1 (en) * 2016-11-16 2020-09-23 Fresenius Kabi Deutschland GmbH Nutritional composition for use in therapy of patients with sarcopenia and/or frailty or pre-sarcopenic and/or pre-frail patients
CN108014109B (zh) * 2017-12-27 2019-09-20 浙江科技学院 葫芦巴碱在制备治疗或预防缺氧性损伤的药物或食品中的应用

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US20220241259A1 (en) 2022-08-04
CA3140735A1 (en) 2021-01-14
AU2020310496A1 (en) 2021-12-09
EP3993791A1 (en) 2022-05-11
CN113993546A (zh) 2022-01-28
WO2021004919A1 (en) 2021-01-14
JP2022538154A (ja) 2022-08-31

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