BR112021022613A2 - Métodos de fabricação de canabidiol ou canabidivarina e intermediários de fabricação de canabidiol ou canabidivarina - Google Patents
Métodos de fabricação de canabidiol ou canabidivarina e intermediários de fabricação de canabidiol ou canabidivarinaInfo
- Publication number
- BR112021022613A2 BR112021022613A2 BR112021022613A BR112021022613A BR112021022613A2 BR 112021022613 A2 BR112021022613 A2 BR 112021022613A2 BR 112021022613 A BR112021022613 A BR 112021022613A BR 112021022613 A BR112021022613 A BR 112021022613A BR 112021022613 A2 BR112021022613 A2 BR 112021022613A2
- Authority
- BR
- Brazil
- Prior art keywords
- cannabidivarin
- cannabidiol
- manufacturing
- intermediates
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
- C07C37/50—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by reactions decreasing the number of carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
- C07C37/68—Purification; separation; Use of additives, e.g. for stabilisation
- C07C37/70—Purification; separation; Use of additives, e.g. for stabilisation by physical treatment
- C07C37/74—Purification; separation; Use of additives, e.g. for stabilisation by physical treatment by distillation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
- C07C37/68—Purification; separation; Use of additives, e.g. for stabilisation
- C07C37/70—Purification; separation; Use of additives, e.g. for stabilisation by physical treatment
- C07C37/84—Purification; separation; Use of additives, e.g. for stabilisation by physical treatment by crystallisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/23—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing six-membered aromatic rings and other rings, with unsaturation outside the aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/56—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing hydroxy groups
- C07C47/565—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing hydroxy groups all hydroxy groups bound to the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
- C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/48—Separation; Purification; Stabilisation; Use of additives
- C07C67/52—Separation; Purification; Stabilisation; Use of additives by change in the physical state, e.g. crystallisation
- C07C67/54—Separation; Purification; Stabilisation; Use of additives by change in the physical state, e.g. crystallisation by distillation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
- C07C69/94—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of polycyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
métodos de fabricação de canabidiol ou canabidivarina e intermediários de fabricação de canabidiol ou canabidivarina. apresenta os referidos métodos de fabricação de canabidiol (cbd) e canabidivarina (cbdv); intermediários dos métodos de fabricação de cbd e cbdv; e cbd e cbdv cristalizados obtidos por meio dos métodos descritos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962846279P | 2019-05-10 | 2019-05-10 | |
PCT/IB2020/000365 WO2020229891A1 (en) | 2019-05-10 | 2020-05-08 | Methods of manufacturing cannabidiol or cannabidivarin and intermediates of manufacturing cannabidiol or cannabidivarin |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112021022613A2 true BR112021022613A2 (pt) | 2022-01-04 |
Family
ID=71728760
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112021022613A BR112021022613A2 (pt) | 2019-05-10 | 2020-05-08 | Métodos de fabricação de canabidiol ou canabidivarina e intermediários de fabricação de canabidiol ou canabidivarina |
Country Status (8)
Country | Link |
---|---|
US (1) | US20200354297A1 (pt) |
EP (1) | EP3966190A1 (pt) |
JP (1) | JP2022531807A (pt) |
KR (1) | KR20220007078A (pt) |
CN (1) | CN113950467A (pt) |
BR (1) | BR112021022613A2 (pt) |
CA (1) | CA3139623A1 (pt) |
WO (1) | WO2020229891A1 (pt) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112811980B (zh) * | 2020-12-01 | 2022-03-25 | 山东金城金奥医药科技有限公司 | 一种绿色光氧化连续制备大麻二酚中间体的方法 |
CN114644547A (zh) * | 2020-12-21 | 2022-06-21 | 云南汉盟制药有限公司 | 一种大麻二酚和/或次大麻二酚的制备方法 |
CN115504862A (zh) * | 2021-06-07 | 2022-12-23 | 南通新世元生物科技有限公司 | 一种大麻萜酚的制备方法 |
WO2023046730A1 (de) | 2021-09-22 | 2023-03-30 | Bionorica Se | Kosmetische zusammensetzungen mit cannabidiol und einem extrakt aus zingiber |
CN115385780B (zh) * | 2022-08-26 | 2024-02-27 | 晨光生物科技集团股份有限公司 | 一种次大麻二酚结晶多晶型物及其制备方法和应用 |
KR102641482B1 (ko) | 2023-05-18 | 2024-02-28 | 재단법인춘천바이오산업진흥원 | 고순도의 칸나비디올 정제 및 결정 제조방법 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102009019322A1 (de) * | 2009-04-30 | 2010-11-11 | The Health Concept Gmbh | Verfahren zur Herstellung von Synthetischen Cannabinoiden |
EP2842933B1 (de) * | 2013-09-03 | 2015-07-29 | Symrise AG | Mischungen cannabinoider Verbindungen, deren Herstellung und Verwendung |
EP3061450A1 (de) * | 2015-02-26 | 2016-08-31 | Symrise AG | Mischungen cannabinoider Verbindungen, deren Herstellung und Verwendung |
DK3455213T3 (da) * | 2016-05-13 | 2022-03-07 | Symrise Ag | Fremgangsmåde til at oprense cannabinoid-forbindelser via simulated moving bed-kromatografi |
US10053407B2 (en) * | 2016-06-01 | 2018-08-21 | S&B Pharma, Inc. | Crystalline cannabidivarin |
US10399920B2 (en) * | 2016-06-01 | 2019-09-03 | S&B Pharma, Inc. | Crystalline form of cannabidiol |
-
2020
- 2020-05-08 JP JP2021566988A patent/JP2022531807A/ja active Pending
- 2020-05-08 KR KR1020217038578A patent/KR20220007078A/ko unknown
- 2020-05-08 CN CN202080035125.1A patent/CN113950467A/zh active Pending
- 2020-05-08 WO PCT/IB2020/000365 patent/WO2020229891A1/en unknown
- 2020-05-08 EP EP20743219.6A patent/EP3966190A1/en not_active Withdrawn
- 2020-05-08 US US16/870,637 patent/US20200354297A1/en not_active Abandoned
- 2020-05-08 CA CA3139623A patent/CA3139623A1/en active Pending
- 2020-05-08 BR BR112021022613A patent/BR112021022613A2/pt not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP3966190A1 (en) | 2022-03-16 |
CA3139623A1 (en) | 2020-11-19 |
KR20220007078A (ko) | 2022-01-18 |
CN113950467A (zh) | 2022-01-18 |
WO2020229891A1 (en) | 2020-11-19 |
JP2022531807A (ja) | 2022-07-11 |
US20200354297A1 (en) | 2020-11-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |