BR112021018306A2 - Materiais e métodos para tratamento melhorado e prevenção de biofilmes - Google Patents

Materiais e métodos para tratamento melhorado e prevenção de biofilmes

Info

Publication number
BR112021018306A2
BR112021018306A2 BR112021018306A BR112021018306A BR112021018306A2 BR 112021018306 A2 BR112021018306 A2 BR 112021018306A2 BR 112021018306 A BR112021018306 A BR 112021018306A BR 112021018306 A BR112021018306 A BR 112021018306A BR 112021018306 A2 BR112021018306 A2 BR 112021018306A2
Authority
BR
Brazil
Prior art keywords
biofilms
methods
materials
prevention
improved treatment
Prior art date
Application number
BR112021018306A
Other languages
English (en)
Inventor
Ken Alibek
Sean Farmer
Original Assignee
Locus Ip Co Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Locus Ip Co Llc filed Critical Locus Ip Co Llc
Publication of BR112021018306A2 publication Critical patent/BR112021018306A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/30—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests characterised by the surfactants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7012—Compounds having a free or esterified carboxyl group attached, directly or through a carbon chain, to a carbon atom of the saccharide radical, e.g. glucuronic acid, neuraminic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Toxicology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

materiais e métodos para tratamento e prevenção melhorados de biofilmes. a invenção do sujeito fornece materiais e métodos para prevenir, inibir ou reduzir a formação de biofilme e infecções de biofilme. a invenção utiliza subprodutos do crescimento de microrganismos benéficos para aumentar a eficácia das substâncias biocidas no tratamento, perturbação e/ou prevenção de biofilmes. vantajosamente, a invenção do sujeito é útil contra estirpes bacterianas resistentes aos antibióticos, tais como mrsa e certas estirpes de helicobacter pylori.
BR112021018306A 2019-03-15 2020-03-13 Materiais e métodos para tratamento melhorado e prevenção de biofilmes BR112021018306A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962819000P 2019-03-15 2019-03-15
US201962846079P 2019-05-10 2019-05-10
PCT/US2020/022591 WO2020190699A1 (en) 2019-03-15 2020-03-13 Materials and methods for enhanced treatment and prevention of biofilms

Publications (1)

Publication Number Publication Date
BR112021018306A2 true BR112021018306A2 (pt) 2022-01-25

Family

ID=72520453

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112021018306A BR112021018306A2 (pt) 2019-03-15 2020-03-13 Materiais e métodos para tratamento melhorado e prevenção de biofilmes

Country Status (12)

Country Link
US (1) US20220142988A1 (pt)
EP (1) EP3937634A4 (pt)
JP (1) JP2022525762A (pt)
KR (1) KR20210129725A (pt)
CN (1) CN113873883A (pt)
AU (1) AU2020241243A1 (pt)
BR (1) BR112021018306A2 (pt)
CA (1) CA3132821A1 (pt)
IL (1) IL286437A (pt)
MX (1) MX2021011147A (pt)
SG (1) SG11202109097UA (pt)
WO (1) WO2020190699A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3212754A1 (en) * 2021-03-26 2022-09-29 Michael Fefer Antibiofilm formulations comprising a polycarboxylic acid derivative, an essential oil, and a select biosurfactant

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI103056B1 (fi) * 1996-08-16 1999-04-15 Orion Yhtymae Oy Menetelmä ja testipakkaus näytteenottopinnan esikäsittelemiseksi
US20020123077A1 (en) * 2000-09-29 2002-09-05 O'toole George A. Novel compounds capable of modulating biofilms
US20070014739A1 (en) * 2005-07-14 2007-01-18 Eldridge Gary R Compositions and methods for controlling biofilms and bacterial infections
JP2012072179A (ja) * 2005-08-30 2012-04-12 Kao Corp バイオフィルム抑制剤
CN102056600A (zh) * 2008-04-07 2011-05-11 界面生物公司 用于治疗细菌感染的组合疗法
CA2744172A1 (en) * 2008-12-10 2010-06-17 Pan-Eco S.A. Biosurfactant composition produced by a new bacillus licheniformis strain, uses and products thereof
US9028878B2 (en) * 2009-02-03 2015-05-12 Microbion Corporation Bismuth-thiols as antiseptics for biomedical uses, including treatment of bacterial biofilms and other uses
WO2011088020A2 (en) * 2010-01-12 2011-07-21 The General Hospital Corporation Modified saponins for the treatment of fungal infections
US20110306569A1 (en) * 2010-06-11 2011-12-15 Oregon State University Rhamnolipid biosurfactant from pseudomonas aeruginosa strain ny3 and methods of use
EP2951311A4 (en) * 2013-02-02 2016-07-13 Synthezyme Llc COMBINATIONS OF MODIFIED SOPHOROLIPIDS AS ANTIMICROBIAL AGENTS
CN104233331B (zh) * 2014-09-11 2016-06-29 南京农业大学 食品不锈钢加工器械表面致病菌生物菌膜的清除方法
EP3614842A4 (en) * 2017-04-29 2021-02-24 Nevada Naturals, Inc. BIOFILM PENETRATING COMPOSITIONS AND PROCESSES

Also Published As

Publication number Publication date
WO2020190699A1 (en) 2020-09-24
SG11202109097UA (en) 2021-09-29
US20220142988A1 (en) 2022-05-12
JP2022525762A (ja) 2022-05-19
IL286437A (en) 2021-10-31
KR20210129725A (ko) 2021-10-28
MX2021011147A (es) 2021-10-22
CN113873883A (zh) 2021-12-31
AU2020241243A1 (en) 2021-09-09
EP3937634A1 (en) 2022-01-19
CA3132821A1 (en) 2020-09-24
EP3937634A4 (en) 2022-11-09

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B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]