BR112021017140A2 - Composições tópicas estáveis de fenoldopam - Google Patents
Composições tópicas estáveis de fenoldopamInfo
- Publication number
- BR112021017140A2 BR112021017140A2 BR112021017140A BR112021017140A BR112021017140A2 BR 112021017140 A2 BR112021017140 A2 BR 112021017140A2 BR 112021017140 A BR112021017140 A BR 112021017140A BR 112021017140 A BR112021017140 A BR 112021017140A BR 112021017140 A2 BR112021017140 A2 BR 112021017140A2
- Authority
- BR
- Brazil
- Prior art keywords
- fenoldopam
- compositions
- composition
- stable topical
- stable
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 6
- TVURRHSHRRELCG-UHFFFAOYSA-N fenoldopam Chemical compound C1=CC(O)=CC=C1C1C2=CC(O)=C(O)C(Cl)=C2CCNC1 TVURRHSHRRELCG-UHFFFAOYSA-N 0.000 title abstract 5
- 229960002724 fenoldopam Drugs 0.000 title abstract 5
- 230000000699 topical effect Effects 0.000 title abstract 4
- 239000003349 gelling agent Substances 0.000 abstract 2
- 229920002401 polyacrylamide Polymers 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
composições tópicas estáveis de fenoldopam. a presente divulgação é direcionada a uma composição tópica, por exemplo, uma composição tópica fisicamente e quimicamente estável de fenoldopam compreendendo cerca de 0,1% a cerca de 5% em peso de fenoldopam ou um sal farmaceuticamente aceitável deste, pelo menos um agente gelificante do tipo poliacrilamida, pelo menos um agente gelificante do tipo celulose, e pelo menos um solvente, em que o fenoldopam é substancialmente solubilizado na composição, e em que a composição é estável por pelo menos doze meses a 25oc e 60% de umidade relativa.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962815893P | 2019-03-08 | 2019-03-08 | |
| PCT/IB2020/051967 WO2020183322A1 (en) | 2019-03-08 | 2020-03-06 | Stable topical compositions of fenoldopam |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112021017140A2 true BR112021017140A2 (pt) | 2021-11-09 |
Family
ID=69846519
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112021017140A BR112021017140A2 (pt) | 2019-03-08 | 2020-03-06 | Composições tópicas estáveis de fenoldopam |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US11446237B2 (pt) |
| EP (2) | EP3908255B1 (pt) |
| JP (2) | JP7124234B2 (pt) |
| CN (2) | CN113543773B (pt) |
| AU (2) | AU2020236525B2 (pt) |
| BR (1) | BR112021017140A2 (pt) |
| CA (1) | CA3131049A1 (pt) |
| ES (1) | ES2941241T3 (pt) |
| IL (1) | IL286197A (pt) |
| NZ (1) | NZ781774A (pt) |
| WO (1) | WO2020183322A1 (pt) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023205695A1 (en) * | 2022-04-21 | 2023-10-26 | Glaukos Corporation | Ophthalmic topical cream compositions |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4666828A (en) | 1984-08-15 | 1987-05-19 | The General Hospital Corporation | Test for Huntington's disease |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4801531A (en) | 1985-04-17 | 1989-01-31 | Biotechnology Research Partners, Ltd. | Apo AI/CIII genomic polymorphisms predictive of atherosclerosis |
| US5272057A (en) | 1988-10-14 | 1993-12-21 | Georgetown University | Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase |
| US5192659A (en) | 1989-08-25 | 1993-03-09 | Genetype Ag | Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes |
| PT766557E (pt) | 1994-06-23 | 2002-05-31 | Procter & Gamble | Composicoes de aplicacao topica compreendendo n-acetil-cisteina |
| US6054429A (en) | 1996-03-08 | 2000-04-25 | Elan Pharmaceuticals, Inc. | Epidural method of producing analgesia |
| WO1999055341A1 (en) | 1998-04-27 | 1999-11-04 | Elan Pharmaceuticals, Inc. | Transdermal administration of fenoldopam |
| JPH11335236A (ja) | 1998-05-22 | 1999-12-07 | Shiseido Co Ltd | 皮膚外用剤 |
| US6699497B1 (en) | 1998-07-24 | 2004-03-02 | Alza Corporation | Formulations for the transdermal administration of fenoldopam |
| JP2002521324A (ja) | 1998-07-24 | 2002-07-16 | アルザ コーポレイション | フェノルドパムの経皮投与のための配合物 |
| US7442369B1 (en) * | 2000-08-09 | 2008-10-28 | Mcneil Ab | Compositions of minoxidil |
| US7358236B1 (en) | 2002-06-21 | 2008-04-15 | Oxigene, Inc. | Control of acute hypertension and cardiotoxicity in patients treated with vascular targeting agents |
| US7820145B2 (en) | 2003-08-04 | 2010-10-26 | Foamix Ltd. | Oleaginous pharmaceutical and cosmetic foam |
| US20050267176A1 (en) | 2004-02-18 | 2005-12-01 | Sepracor Inc. | Dopamine-agonist combination therapy for improving sleep quality |
| EP1745036A2 (en) | 2004-05-03 | 2007-01-24 | Boehringer Ingelheim Pharmaceuticals Inc. | Cytokine inhibitors |
| CN101151028A (zh) * | 2005-03-03 | 2008-03-26 | Isw集团公司 | 局部用凝胶组合物 |
| CN101252951B (zh) | 2005-06-30 | 2011-12-21 | 森托科尔公司 | 抗il-23抗体、组合物、方法和用途 |
| AU2006278514A1 (en) | 2005-08-03 | 2007-02-15 | Mia Levite | Killing human lymphoma and leukemia cancer cells and TCR-activated normal human cells by dopamine D1R agonists |
| WO2009052491A2 (en) | 2007-10-18 | 2009-04-23 | Geraghty, Erin | Fenoldopam formulations and prodrug derivatives |
| WO2009072007A2 (en) | 2007-12-07 | 2009-06-11 | Foamix Ltd. | Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof |
| CN101977599A (zh) | 2007-12-11 | 2011-02-16 | 斯蒂芬·H·门罗 | 用于处理细胞环境和离子通道的缓冲水溶液的组合物及其使用方法 |
| CA2732439A1 (en) | 2008-07-31 | 2010-02-04 | Case Western Reserve University | Halogen-stabilized insulin |
| JP2011144143A (ja) | 2010-01-15 | 2011-07-28 | Shiseido Co Ltd | 皮膚外用剤 |
| AR083651A1 (es) | 2010-10-21 | 2013-03-13 | Galderma Sa | Composiciones de brimonidina en gel y metodos de uso |
| ES2640572T3 (es) | 2011-04-28 | 2017-11-03 | Platform Brightworks Two, Ltd. | Formulaciones parenterales mejoradas de agentes farmacéuticos lipófilos y procedimientos de preparación y uso de las mismas |
| FR2991177B1 (fr) | 2012-06-01 | 2014-12-19 | Galderma Res & Dev | Compositions topiques, contenant un retinoide, de type emulsion huile dans eau sans emulsionnant |
| AU2014227996B2 (en) * | 2013-03-15 | 2018-08-23 | Vapogenix, Inc. | Novel analgesic compositions |
| WO2016021599A1 (ja) | 2014-08-04 | 2016-02-11 | 日東電工株式会社 | 液性免疫誘導促進用組成物及びワクチン医薬組成物 |
| RU2711090C2 (ru) | 2015-01-23 | 2020-01-15 | Др. Редди'С Лабораториз Лимитед | Неокрашивающая гелевая композиция, содержащая нимесулид, для местного применения |
| EP3506906A4 (en) | 2016-08-31 | 2020-08-12 | Taro Pharmaceutical Industries Ltd. | TOPICAL FENOLDOPAM FORMULATIONS FOR THE TREATMENT OF SKIN DISEASES |
| CN111343969A (zh) * | 2017-10-24 | 2020-06-26 | 格兰马克药品有限公司 | 阿达帕林和米诺环素的局部药物组合物 |
-
2020
- 2020-03-06 CN CN202080019392.XA patent/CN113543773B/zh active Active
- 2020-03-06 NZ NZ781774A patent/NZ781774A/en not_active IP Right Cessation
- 2020-03-06 US US17/430,264 patent/US11446237B2/en active Active
- 2020-03-06 BR BR112021017140A patent/BR112021017140A2/pt active Search and Examination
- 2020-03-06 WO PCT/IB2020/051967 patent/WO2020183322A1/en unknown
- 2020-03-06 AU AU2020236525A patent/AU2020236525B2/en not_active Ceased
- 2020-03-06 EP EP20712690.5A patent/EP3908255B1/en active Active
- 2020-03-06 JP JP2021553117A patent/JP7124234B2/ja active Active
- 2020-03-06 EP EP23150539.7A patent/EP4218719A3/en not_active Withdrawn
- 2020-03-06 CA CA3131049A patent/CA3131049A1/en active Pending
- 2020-03-06 ES ES20712690T patent/ES2941241T3/es active Active
- 2020-03-06 CN CN202310774370.XA patent/CN116966129A/zh active Pending
-
2021
- 2021-09-06 IL IL286197A patent/IL286197A/en unknown
-
2022
- 2022-05-03 AU AU2022202941A patent/AU2022202941A1/en not_active Abandoned
- 2022-08-09 US US17/883,687 patent/US20230059107A1/en not_active Abandoned
- 2022-08-10 JP JP2022127610A patent/JP2022160648A/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| ES2941241T3 (es) | 2023-05-19 |
| IL286197A (en) | 2021-10-31 |
| JP2022160648A (ja) | 2022-10-19 |
| AU2022202941A1 (en) | 2022-05-26 |
| US20220040089A1 (en) | 2022-02-10 |
| CN113543773B (zh) | 2023-07-14 |
| EP4218719A2 (en) | 2023-08-02 |
| EP3908255B1 (en) | 2023-01-11 |
| EP4218719A3 (en) | 2023-09-20 |
| JP2022515569A (ja) | 2022-02-18 |
| JP7124234B2 (ja) | 2022-08-23 |
| AU2020236525B2 (en) | 2022-02-03 |
| AU2020236525A1 (en) | 2021-11-04 |
| EP3908255A1 (en) | 2021-11-17 |
| CA3131049A1 (en) | 2020-09-17 |
| WO2020183322A1 (en) | 2020-09-17 |
| NZ781774A (en) | 2023-03-31 |
| CN113543773A (zh) | 2021-10-22 |
| CN116966129A (zh) | 2023-10-31 |
| US20230059107A1 (en) | 2023-02-23 |
| US11446237B2 (en) | 2022-09-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BRPI0805634A2 (pt) | composição de concentrado de suspensão (sc) aquosa, método para prepararum concentrado de suspensão, composição de proteção de cultura, método para proteger culturas no local , uso de composição e método para impedir aglomeração de partìculas em um concentrado de suspensão | |
| AR098830A2 (es) | Suspensiones acuosas estabilizadas para administración parenteral | |
| BR112015019657A2 (pt) | composições tópicas e métodos de uso das mesmas | |
| BR112018004642A2 (pt) | processo para tratamento capilar | |
| BRPI0500704A (pt) | composições de tratamento pessoal reidratáveis | |
| BR112022002892A2 (pt) | Trombossomos como um agente de reversão de agente antiplaqueta | |
| BR112019000849A2 (pt) | composições líquidas de limpeza com sistema antibacteriano e método de fabricação das mesmas | |
| BR112015017405A2 (pt) | composições que incluem agentes hidrofobizantes e estabilizantes e métodos para preparação e utilização das mesmas | |
| DK1471887T3 (da) | Nanopartikelkompositioner der har lysozym som overfladestabiliseringsmiddel | |
| BR112020019875A8 (pt) | composições tópicas para alívio da dor | |
| BR0110898A (pt) | Composição anidra antiperspirante em bastão | |
| BRPI0416752B8 (pt) | composição farmacêutica, uso de um ou mais compostos, e, compostos | |
| BRPI0519605A2 (pt) | composiÇÕes de cuidado pessoal | |
| BR9907309A (pt) | FluorelastÈmeros curáveis, seu uso e processo para a obtenção dos mesmos | |
| BR112017022104A2 (pt) | composição de borracha reticulável, uso da composição, e processo de retícula de composição de borracha | |
| BR112021017140A2 (pt) | Composições tópicas estáveis de fenoldopam | |
| BR112014001493A2 (pt) | montante para uso na indústria de fundição, composição moldável para a produção de montantes para a indústria de fundição, processo para a preparação de uma composição moldável para a produção de montantes para a indústria de fundição e uso da cinza de casca de arroz | |
| BR112021017612A2 (pt) | Película geradora de aerossol | |
| UY38068A (es) | Péptidos de la cadena b de la relaxina lipidados modificados y su uso terapéutico | |
| BR112022022452A2 (pt) | Inibidores de il4i1 e métodos de uso | |
| BR112023023129A2 (pt) | Composições orais e métodos relacionados para reduzir a irritação da garganta | |
| BRMU8603015U (pt) | agente farmacêutico contendo hialuronano como componente ativo | |
| BR112021023445A2 (pt) | Composição farmacêutica do composto de piridina amina e aplicação da mesma em câncer de pulmão de células não pequenas ros1-positivo | |
| BR112023003471A2 (pt) | Composição geradora de aerossol , artigo, sistema de provisão de aerossol e seu uso, pasta , método de produção de uma composição geradora de aerossol , método para gerar um aerossol | |
| BR112014010564A2 (pt) | composições melhoradas |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B11D | Dismissal acc. art. 38, par 2 of ipl - failure to pay fee after grant in time |