BR112021011557A2 - Formulação complexa e composição farmacêutica incluindo insulina e glucagon - Google Patents
Formulação complexa e composição farmacêutica incluindo insulina e glucagon Download PDFInfo
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- BR112021011557A2 BR112021011557A2 BR112021011557-9A BR112021011557A BR112021011557A2 BR 112021011557 A2 BR112021011557 A2 BR 112021011557A2 BR 112021011557 A BR112021011557 A BR 112021011557A BR 112021011557 A2 BR112021011557 A2 BR 112021011557A2
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- cysteine
- insulin
- amino acid
- glucagon
- pharmaceutical composition
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- A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2018-0167798 | 2018-12-21 | ||
| KR20180167798 | 2018-12-21 | ||
| PCT/KR2019/018320 WO2020130751A1 (ko) | 2018-12-21 | 2019-12-23 | 인슐린 및 글루카곤을 포함하는 약학 조성물 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112021011557A2 true BR112021011557A2 (pt) | 2021-09-14 |
Family
ID=71102651
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112021011557-9A BR112021011557A2 (pt) | 2018-12-21 | 2019-12-23 | Formulação complexa e composição farmacêutica incluindo insulina e glucagon |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20220064248A1 (https=) |
| EP (1) | EP3900734A4 (https=) |
| JP (2) | JP2022514835A (https=) |
| KR (1) | KR20200078414A (https=) |
| CN (1) | CN113365651A (https=) |
| AU (1) | AU2019405389B2 (https=) |
| BR (1) | BR112021011557A2 (https=) |
| CA (1) | CA3124340A1 (https=) |
| MX (1) | MX2021007124A (https=) |
| WO (1) | WO2020130751A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113453703A (zh) * | 2018-12-21 | 2021-09-28 | 韩美药品株式会社 | 包括胰岛素和对胰高血糖素和glp-1和gip受体均具有活性的三重激动剂的药物组合物 |
| EP4183407A4 (en) * | 2020-07-15 | 2024-08-14 | Hanmi Pharm. Co., Ltd. | THERAPEUTIC USE OF A GLUCAGNONE DERIVATIVE OR CONJUGATE THEREOF FOR LIVER DISEASES |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6096871A (en) | 1995-04-14 | 2000-08-01 | Genentech, Inc. | Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life |
| JP4046354B2 (ja) | 1996-03-18 | 2008-02-13 | ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム | 増大した半減期を有する免疫グロブリン様ドメイン |
| US7314859B2 (en) * | 2002-12-27 | 2008-01-01 | Diobex, Inc. | Compositions and methods for the prevention and control of insulin-induced hypoglycemia |
| AR081066A1 (es) * | 2010-04-02 | 2012-06-06 | Hanmi Holdings Co Ltd | Conjugado de insulina donde se usa un fragmento de inmunoglobulina |
| KR20140043709A (ko) * | 2011-01-20 | 2014-04-10 | 질랜드 파마 에이/에스 | 아실화 글루카곤 유사체와 인슐린 유사체의 조합 |
| DK2963056T3 (da) | 2013-02-26 | 2020-02-17 | Hanmi Pharm Ind Co Ltd | Insulinanalog og anvendelse deraf |
| AR100695A1 (es) * | 2014-05-30 | 2016-10-26 | Hanmi Pharm Ind Co Ltd | Composición para el tratamiento de diabetes mellitus que comprende insulina y un agonista dual glp-1 / glucagón |
| WO2015189698A2 (en) | 2014-06-08 | 2015-12-17 | Beijing Cosci-Remd Bio Med Tech Company Ltd | Methods for treating type 1 diabetes using glucagon receptor antagonistic antibodies |
| PE20171154A1 (es) * | 2014-12-30 | 2017-08-16 | Hanmi Pharm Ind Co Ltd | Derivados de glucagon con estabilidad mejorada |
| EP4523705A3 (en) * | 2015-06-30 | 2025-06-11 | Hanmi Pharm. Co., Ltd. | Glucagon derivative and a composition comprising a long acting conjugate of the same |
| UY36870A (es) | 2015-08-28 | 2017-03-31 | Hanmi Pharm Ind Co Ltd | Análogos de insulina novedosos |
| WO2017052329A1 (en) * | 2015-09-24 | 2017-03-30 | Hanmi Pharm. Co., Ltd. | Protein complex by use of a specific site of an immunoglobulin fragment for linkage |
| TW201718629A (zh) * | 2015-09-25 | 2017-06-01 | 韓美藥品股份有限公司 | 包含多個生理多肽及免疫球蛋白Ｆｃ區之蛋白質接合物 |
| EP3479841A4 (en) * | 2016-06-29 | 2020-03-04 | Hanmi Pharm. Co., Ltd. | GLUCAGON DERIVATIVE, CONJUGATE THEREOF, COMPOSITION THEREOF AND THERAPEUTIC USE THEREOF |
| WO2018144867A1 (en) * | 2017-02-03 | 2018-08-09 | Vanderbilt University | Systems, compositions and methods for treating diabetes |
| CN110545849A (zh) * | 2017-02-03 | 2019-12-06 | 韩美药品株式会社 | 具有增加的持续性的生理活性物质的缀合物及其应用 |
| GB201710822D0 (en) * | 2017-07-05 | 2017-08-16 | Zealand Pharma As | Methods and medical uses relating to the treatment of hypoglycaemia |
-
2019
- 2019-12-23 KR KR1020190173205A patent/KR20200078414A/ko active Pending
- 2019-12-23 CA CA3124340A patent/CA3124340A1/en active Pending
- 2019-12-23 BR BR112021011557-9A patent/BR112021011557A2/pt unknown
- 2019-12-23 AU AU2019405389A patent/AU2019405389B2/en active Active
- 2019-12-23 EP EP19897547.6A patent/EP3900734A4/en active Pending
- 2019-12-23 CN CN201980090567.3A patent/CN113365651A/zh active Pending
- 2019-12-23 MX MX2021007124A patent/MX2021007124A/es unknown
- 2019-12-23 WO PCT/KR2019/018320 patent/WO2020130751A1/ko not_active Ceased
- 2019-12-23 JP JP2021534266A patent/JP2022514835A/ja active Pending
- 2019-12-23 US US17/415,474 patent/US20220064248A1/en active Pending
-
2024
- 2024-08-29 JP JP2024147410A patent/JP2024178193A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020130751A1 (ko) | 2020-06-25 |
| CN113365651A (zh) | 2021-09-07 |
| AU2019405389A1 (en) | 2021-06-24 |
| US20220064248A1 (en) | 2022-03-03 |
| MX2021007124A (es) | 2021-08-11 |
| EP3900734A1 (en) | 2021-10-27 |
| JP2024178193A (ja) | 2024-12-24 |
| JP2022514835A (ja) | 2022-02-16 |
| CA3124340A1 (en) | 2020-06-25 |
| AU2019405389B2 (en) | 2025-06-05 |
| EP3900734A4 (en) | 2022-10-12 |
| KR20200078414A (ko) | 2020-07-01 |
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