BR112021001984A2 - composto, combinação, composição farmacêutica, conjunto de partes, uso de composto, e, método para tratamento de uma doença resultante de inflamação patológica - Google Patents
composto, combinação, composição farmacêutica, conjunto de partes, uso de composto, e, método para tratamento de uma doença resultante de inflamação patológica Download PDFInfo
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- BR112021001984A2 BR112021001984A2 BR112021001984-7A BR112021001984A BR112021001984A2 BR 112021001984 A2 BR112021001984 A2 BR 112021001984A2 BR 112021001984 A BR112021001984 A BR 112021001984A BR 112021001984 A2 BR112021001984 A2 BR 112021001984A2
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- Prior art keywords
- compound
- alkyl
- ethyl
- hydrogen
- diethylamino
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Classifications
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- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
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- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
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- A—HUMAN NECESSITIES
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- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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- A—HUMAN NECESSITIES
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- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
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- A61K31/60—Salicylic acid; Derivatives thereof
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- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
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- A61K31/655—Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/30—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to hydrogen atoms or to acyclic carbon atoms
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18189194 | 2018-08-15 | ||
| EP18189194.6 | 2018-08-15 | ||
| PCT/EP2019/071903 WO2020035554A1 (en) | 2018-08-15 | 2019-08-15 | A new medical treatment for pathologic inflammation |
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| Publication Number | Publication Date |
|---|---|
| BR112021001984A2 true BR112021001984A2 (pt) | 2021-05-11 |
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| Country | Link |
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| US (1) | US11896564B2 (https=) |
| EP (1) | EP3836912B1 (https=) |
| JP (1) | JP7512251B2 (https=) |
| CN (1) | CN112770736B (https=) |
| AU (1) | AU2019322564A1 (https=) |
| BR (1) | BR112021001984A2 (https=) |
| CA (1) | CA3108361A1 (https=) |
| IL (1) | IL280548A (https=) |
| MX (1) | MX2021001349A (https=) |
| WO (1) | WO2020035554A1 (https=) |
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| US11717500B2 (en) * | 2020-02-03 | 2023-08-08 | Pharmacyl Ab | Treatment of spondyloarthritis |
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| US6100299A (en) | 1996-03-08 | 2000-08-08 | Oxigene, Inc. | N-acetyl 3-chloroprocainamide, acid addition salts thereof, and methods of use |
| US6028111A (en) | 1996-03-08 | 2000-02-22 | Oxigene, Inc. | Compositions and use of benzamides and nicotinamides as anti-inflammatory agents |
| US6518312B2 (en) | 2000-07-05 | 2003-02-11 | Active Biotech Ab | Immune enhancement |
| US7157444B2 (en) | 2002-12-21 | 2007-01-02 | Deanna Jean Nelson | Aminosalicylate derivatives for treatment of inflammatory bowel disease |
| WO2005025498A2 (en) | 2003-09-08 | 2005-03-24 | Corus Pharma | Substituted acetanilides and benzamides for the treatment of asthma and pulmonary inflammation |
| SE0400235D0 (sv) | 2004-02-06 | 2004-02-06 | Active Biotech Ab | New composition containing quinoline compounds |
| DE102004011720B4 (de) | 2004-03-10 | 2008-04-03 | Bayer Schering Pharma Aktiengesellschaft | Radiohalogenierte Benzamidderivate und deren Verwendung in der Tumordiagnostik und Tumortherapie |
| ATE554770T1 (de) * | 2006-04-13 | 2012-05-15 | Taiho Pharmaceutical Co Ltd | Therapeutisches mittel gegen entzündliche darmerkrankungen |
| PT2123277E (pt) * | 2007-12-18 | 2011-04-20 | Meiji Seika Kaisha | Agente preventivo ou terapêutico para doenças inflamatórias do intestino |
| WO2018037103A1 (en) | 2016-08-26 | 2018-03-01 | Idogen Ab | Procainamide for treating immune disorders and for modulating ido expression |
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| MX2021001349A (es) | 2021-04-13 |
| CN112770736A (zh) | 2021-05-07 |
| US11896564B2 (en) | 2024-02-13 |
| CA3108361A1 (en) | 2020-02-20 |
| WO2020035554A1 (en) | 2020-02-20 |
| EP3836912B1 (en) | 2024-05-01 |
| JP7512251B2 (ja) | 2024-07-08 |
| EP3836912A1 (en) | 2021-06-23 |
| US20220087959A1 (en) | 2022-03-24 |
| IL280548A (en) | 2021-03-25 |
| EP3836912C0 (en) | 2024-05-01 |
| JP2022501315A (ja) | 2022-01-06 |
| CN112770736B (zh) | 2025-01-21 |
| KR20210045414A (ko) | 2021-04-26 |
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