BR112020023310B1 - Composição tópica - Google Patents
Composição tópica Download PDFInfo
- Publication number
- BR112020023310B1 BR112020023310B1 BR112020023310-2A BR112020023310A BR112020023310B1 BR 112020023310 B1 BR112020023310 B1 BR 112020023310B1 BR 112020023310 A BR112020023310 A BR 112020023310A BR 112020023310 B1 BR112020023310 B1 BR 112020023310B1
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- BR
- Brazil
- Prior art keywords
- weight
- panthenol
- composition
- range
- bemt
- Prior art date
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- 239000000203 mixture Substances 0.000 title claims abstract description 118
- TXFPEBPIARQUIG-UHFFFAOYSA-N 4'-hydroxyacetophenone Chemical compound CC(=O)C1=CC=C(O)C=C1 TXFPEBPIARQUIG-UHFFFAOYSA-N 0.000 claims abstract description 125
- 230000000699 topical effect Effects 0.000 claims abstract description 55
- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 claims abstract description 54
- 235000004866 D-panthenol Nutrition 0.000 claims abstract description 51
- 239000011703 D-panthenol Substances 0.000 claims abstract description 51
- 229960003949 dexpanthenol Drugs 0.000 claims abstract description 50
- 238000010186 staining Methods 0.000 claims abstract description 11
- XVAMCHGMPYWHNL-UHFFFAOYSA-N bemotrizinol Chemical compound OC1=CC(OCC(CC)CCCC)=CC=C1C1=NC(C=2C=CC(OC)=CC=2)=NC(C=2C(=CC(OCC(CC)CCCC)=CC=2)O)=N1 XVAMCHGMPYWHNL-UHFFFAOYSA-N 0.000 claims description 95
- 238000000034 method Methods 0.000 claims description 20
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- 238000005406 washing Methods 0.000 claims description 8
- 239000008346 aqueous phase Substances 0.000 claims description 4
- RMGVATURDVPNOZ-UHFFFAOYSA-M potassium;hexadecyl hydrogen phosphate Chemical compound [K+].CCCCCCCCCCCCCCCCOP(O)([O-])=O RMGVATURDVPNOZ-UHFFFAOYSA-M 0.000 claims description 4
- 239000008194 pharmaceutical composition Substances 0.000 claims description 3
- ZUVCYFMOHFTGDM-UHFFFAOYSA-N hexadecyl dihydrogen phosphate Chemical compound CCCCCCCCCCCCCCCCOP(O)(O)=O ZUVCYFMOHFTGDM-UHFFFAOYSA-N 0.000 claims description 2
- 238000010348 incorporation Methods 0.000 claims description 2
- AKUPYGILGNUOIG-UHFFFAOYSA-N 5-methoxy-4-phenyltriazine Chemical compound COC1=CN=NN=C1C1=CC=CC=C1 AKUPYGILGNUOIG-UHFFFAOYSA-N 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 description 19
- 229910019142 PO4 Inorganic materials 0.000 description 17
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- -1 benzophenon-3 Chemical compound 0.000 description 15
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- OSCJHTSDLYVCQC-UHFFFAOYSA-N 2-ethylhexyl 4-[[4-[4-(tert-butylcarbamoyl)anilino]-6-[4-(2-ethylhexoxycarbonyl)anilino]-1,3,5-triazin-2-yl]amino]benzoate Chemical compound C1=CC(C(=O)OCC(CC)CCCC)=CC=C1NC1=NC(NC=2C=CC(=CC=2)C(=O)NC(C)(C)C)=NC(NC=2C=CC(=CC=2)C(=O)OCC(CC)CCCC)=N1 OSCJHTSDLYVCQC-UHFFFAOYSA-N 0.000 description 8
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- FDATWRLUYRHCJE-UHFFFAOYSA-N diethylamino hydroxybenzoyl hexyl benzoate Chemical compound CCCCCCOC(=O)C1=CC=CC=C1C(=O)C1=CC=C(N(CC)CC)C=C1O FDATWRLUYRHCJE-UHFFFAOYSA-N 0.000 description 5
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- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 description 3
- XDOFQFKRPWOURC-UHFFFAOYSA-N 16-methylheptadecanoic acid Chemical class CC(C)CCCCCCCCCCCCCCC(O)=O XDOFQFKRPWOURC-UHFFFAOYSA-N 0.000 description 3
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- HBXWUCXDUUJDRB-UHFFFAOYSA-N 1-octadecoxyoctadecane Chemical compound CCCCCCCCCCCCCCCCCCOCCCCCCCCCCCCCCCCCC HBXWUCXDUUJDRB-UHFFFAOYSA-N 0.000 description 2
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- YBGZDTIWKVFICR-JLHYYAGUSA-N Octyl 4-methoxycinnamic acid Chemical compound CCCCC(CC)COC(=O)\C=C\C1=CC=C(OC)C=C1 YBGZDTIWKVFICR-JLHYYAGUSA-N 0.000 description 2
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- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 2
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- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 2
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- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 2
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- 125000000913 palmityl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 2
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4966—Triazines or their condensed derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
- A61K8/062—Oil-in-water emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/24—Phosphorous; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/10—General cosmetic use
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Emergency Medicine (AREA)
- Inorganic Chemistry (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18173222.3 | 2018-05-18 | ||
| EP18173222 | 2018-05-18 | ||
| PCT/EP2019/062206 WO2019219606A1 (en) | 2018-05-18 | 2019-05-13 | Topical composition |
Publications (2)
| Publication Number | Publication Date |
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| BR112020023310A2 BR112020023310A2 (pt) | 2021-02-02 |
| BR112020023310B1 true BR112020023310B1 (pt) | 2023-12-12 |
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|---|---|---|---|
| BR112020023310-2A BR112020023310B1 (pt) | 2018-05-18 | 2019-05-13 | Composição tópica |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US11547646B2 (https=) |
| EP (1) | EP3793513B1 (https=) |
| JP (1) | JP7326661B2 (https=) |
| KR (1) | KR102783099B1 (https=) |
| CN (1) | CN112118825B (https=) |
| BR (1) | BR112020023310B1 (https=) |
| ES (1) | ES2925359T3 (https=) |
| WO (1) | WO2019219606A1 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4340804B1 (en) * | 2021-05-19 | 2026-02-04 | DSM IP Assets B.V. | Sunscreen composition comprising bemotrizinol |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8711824D0 (en) | 1987-05-19 | 1987-06-24 | Emhart Ind | Control of pusher mechanisms |
| US6391334B1 (en) * | 1999-10-25 | 2002-05-21 | Amway Corporation | Barrier-forming composition |
| BRPI0721945B1 (pt) * | 2007-08-07 | 2022-04-12 | Symrise Ag | Uso da troxerutina e de uma mistura, método para a dissipação da fluorescência do ácido dissódio fenil dibenzimidazol tetrassulfônico e preparação |
| DE102012224158A1 (de) | 2012-12-21 | 2014-06-26 | Beiersdorf Ag | Kosmetische Emulsion mit Silica Dimethyl Silylate |
| ES2643590T3 (es) * | 2014-03-18 | 2017-11-23 | Symrise Ag | Dióxido de titanio revestido para reducir el efecto de blanqueamiento en la piel |
| DE102014104257A1 (de) * | 2014-03-26 | 2015-10-01 | Beiersdorf Ag | Wirkstoffkombinationen aus Ethylhexyl-2-cyano-3,3-diphenylacrylat und 4-Hydroxyacetophenon sowie kosmetische oder dermatologische Zubereitungen, diese Wirkstoffkombinationen enthaltend |
| DE102014207935A1 (de) * | 2014-04-28 | 2015-10-29 | Beiersdorf Ag | Sonnenschutzmittel mit reduzierter Neigung zur Textilverfleckung III |
| DE102016205580A1 (de) * | 2016-04-05 | 2017-10-05 | Beiersdorf Ag | Neues Sonnenschutzmittel mit reduzierter Neigung zur Textilverfleckung |
| DE102016211239A1 (de) * | 2016-06-23 | 2017-12-28 | Beiersdorf Ag | Neustes Sonnenschutzmittel mit reduzierter Neigung zur Textilverfleckung |
| DE102016211238A1 (de) * | 2016-06-23 | 2017-12-28 | Beiersdorf Ag | Sonnenschutzmittel mit reduzierter Textilverfleckung |
| DE102018203498A1 (de) | 2018-03-08 | 2019-09-12 | Beiersdorf Ag | Sonnenschutzmittel mit reduzierter Textilverfleckung enthaltend hydriertes Pflanzenöl und eine UV-Filterkombination aus Ethylhexyl Triazone und 4-(tert.-Butyl)-4'-methoxydibenzoylmethan |
-
2019
- 2019-05-13 US US17/056,256 patent/US11547646B2/en active Active
- 2019-05-13 BR BR112020023310-2A patent/BR112020023310B1/pt active IP Right Grant
- 2019-05-13 EP EP19722914.9A patent/EP3793513B1/en active Active
- 2019-05-13 CN CN201980032719.4A patent/CN112118825B/zh active Active
- 2019-05-13 KR KR1020207035768A patent/KR102783099B1/ko active Active
- 2019-05-13 JP JP2020564157A patent/JP7326661B2/ja active Active
- 2019-05-13 WO PCT/EP2019/062206 patent/WO2019219606A1/en not_active Ceased
- 2019-05-13 ES ES19722914T patent/ES2925359T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3793513B1 (en) | 2022-06-22 |
| WO2019219606A1 (en) | 2019-11-21 |
| EP3793513A1 (en) | 2021-03-24 |
| JP2021523199A (ja) | 2021-09-02 |
| CN112118825B (zh) | 2023-03-31 |
| US11547646B2 (en) | 2023-01-10 |
| KR102783099B1 (ko) | 2025-03-19 |
| CN112118825A (zh) | 2020-12-22 |
| KR20210010892A (ko) | 2021-01-28 |
| BR112020023310A2 (pt) | 2021-02-02 |
| ES2925359T3 (es) | 2022-10-17 |
| US20210212915A1 (en) | 2021-07-15 |
| JP7326661B2 (ja) | 2023-08-16 |
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| B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
| B06W | Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
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