BR112019004920A2 - sistemas, métodos e assinaturas de genes para prever um status biológico de um indivíduo - Google Patents

sistemas, métodos e assinaturas de genes para prever um status biológico de um indivíduo

Info

Publication number
BR112019004920A2
BR112019004920A2 BR112019004920A BR112019004920A BR112019004920A2 BR 112019004920 A2 BR112019004920 A2 BR 112019004920A2 BR 112019004920 A BR112019004920 A BR 112019004920A BR 112019004920 A BR112019004920 A BR 112019004920A BR 112019004920 A2 BR112019004920 A2 BR 112019004920A2
Authority
BR
Brazil
Prior art keywords
predict
methods
subject
signatures
individual
Prior art date
Application number
BR112019004920A
Other languages
English (en)
Inventor
Poussin Carine
Martin Florian
Peitsch Manuel
Boue Stephanie
Belcastro Vincenzo
Original Assignee
Philip Morris Products Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philip Morris Products Sa filed Critical Philip Morris Products Sa
Publication of BR112019004920A2 publication Critical patent/BR112019004920A2/pt

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Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F42/00—Simulated smoking devices other than electrically operated; Component parts thereof; Manufacture or testing thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H70/00—ICT specially adapted for the handling or processing of medical references
    • G16H70/60—ICT specially adapted for the handling or processing of medical references relating to pathologies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20—Supervised data analysis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Evolutionary Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Artificial Intelligence (AREA)
  • Primary Health Care (AREA)
  • Bioethics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Data Mining & Analysis (AREA)
  • Databases & Information Systems (AREA)
  • Evolutionary Computation (AREA)
  • Software Systems (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

sistemas e métodos para avaliar a amostra de um sujeito para prever o status biológico do sujeito, como o status de fumo. o método implementado por computador inclui o recebimento, por um sistema de computador, incluindo pelo menos um processador de hardware, um conjunto de dados associado à amostra. o conjunto de dados compreende dados de expressão quantitativa para um conjunto de genes menor que um genoma inteiro, o conjunto de genes compreendendo ahhr, cdkn1c, lrrn3, pid1, gpr15, sash1, clec10a, linc00599, p2ry6, dsc2, f2r, sema6b e tlr5. pelo menos um processador de hardware gera uma pontuação baseada nos dados de expressão quantitativa para o conjunto de genes no conjunto de dados recebido, em que a pontuação é baseada em menos de 40 genes e é indicativa de um status de fumo previsto do sujeito.
BR112019004920A 2016-09-14 2017-05-30 sistemas, métodos e assinaturas de genes para prever um status biológico de um indivíduo BR112019004920A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662394551P 2016-09-14 2016-09-14
PCT/EP2017/063073 WO2018050299A1 (en) 2016-09-14 2017-05-30 Systems, methods, and gene signatures for predicting a biological status of an individual

Publications (1)

Publication Number Publication Date
BR112019004920A2 true BR112019004920A2 (pt) 2019-06-04

Family

ID=59021473

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112019004920A BR112019004920A2 (pt) 2016-09-14 2017-05-30 sistemas, métodos e assinaturas de genes para prever um status biológico de um indivíduo

Country Status (9)

Country Link
US (1) US20190244677A1 (pt)
EP (1) EP3513344A1 (pt)
JP (2) JP7022119B2 (pt)
KR (2) KR102421109B1 (pt)
CN (1) CN109643584A (pt)
BR (1) BR112019004920A2 (pt)
CA (1) CA3036597C (pt)
MX (1) MX2019002316A (pt)
WO (1) WO2018050299A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102517328B1 (ko) * 2021-03-31 2023-04-04 주식회사 크라우드웍스 작업툴을 이용한 이미지 내 세포 분별에 관한 작업 수행 방법 및 프로그램
CN113159571A (zh) * 2021-04-20 2021-07-23 中国农业大学 一种跨境外来物种风险等级判定及智能识别方法及系统

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1633892A4 (en) * 2003-06-10 2007-10-24 Univ Boston METHODS OF DETECTING PULMONARY DISORDERS
JP2006314315A (ja) 2005-05-10 2006-11-24 Synergenz Bioscience Ltd 肺の機能と異常を調べるための方法と組成物
WO2007103541A2 (en) * 2006-03-09 2007-09-13 The Trustees Of Boston University Diagnostic and prognostic methods for lung disorders using gene expression profiles from nose epithelial cells
WO2009121070A1 (en) 2008-03-28 2009-10-01 The Trustees Of Boston University Multifactorial methods for detecting lung disorders
JP6257125B2 (ja) * 2008-11-17 2018-01-10 ベラサイト インコーポレイテッド 疾患診断のための分子プロファイリングの方法および組成物
WO2010099161A1 (en) 2009-02-26 2010-09-02 The Ohio State University Research Foundation Micrornas in never-smokers and related materials and methods
US20120245952A1 (en) * 2011-03-23 2012-09-27 University Of Rochester Crowdsourcing medical expertise
CA2846837A1 (en) * 2011-08-29 2013-03-07 Cardiodx, Inc. Methods and compositions for determining smoking status
US10329618B2 (en) * 2012-09-06 2019-06-25 Duke University Diagnostic markers for platelet function and methods of use
CN106415563B (zh) * 2013-12-16 2020-06-05 菲利普莫里斯生产公司 用于预测个体的吸烟状况的系统和方法
US20160130656A1 (en) * 2014-07-14 2016-05-12 Allegro Diagnostics Corp. Methods for evaluating lung cancer status
CN114606309A (zh) * 2014-11-05 2022-06-10 威拉赛特公司 使用机器学习和高维转录数据的诊断系统和方法

Also Published As

Publication number Publication date
CA3036597A1 (en) 2018-03-22
WO2018050299A1 (en) 2018-03-22
JP2022062189A (ja) 2022-04-19
JP7022119B2 (ja) 2022-02-17
KR20220103819A (ko) 2022-07-22
CN109643584A (zh) 2019-04-16
US20190244677A1 (en) 2019-08-08
MX2019002316A (es) 2019-06-24
CA3036597C (en) 2023-03-28
JP7275334B2 (ja) 2023-05-17
EP3513344A1 (en) 2019-07-24
KR102421109B1 (ko) 2022-07-14
JP2019532410A (ja) 2019-11-07
KR20190046940A (ko) 2019-05-07

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B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]
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