BR112018077045A2 - gerador de ge68/ga68 - Google Patents
gerador de ge68/ga68Info
- Publication number
- BR112018077045A2 BR112018077045A2 BR112018077045-0A BR112018077045A BR112018077045A2 BR 112018077045 A2 BR112018077045 A2 BR 112018077045A2 BR 112018077045 A BR112018077045 A BR 112018077045A BR 112018077045 A2 BR112018077045 A2 BR 112018077045A2
- Authority
- BR
- Brazil
- Prior art keywords
- support material
- inorganic support
- nuclide
- generator
- niobium
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
- G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
- G21G1/0005—Isotope delivery systems
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
- G21G4/00—Radioactive sources
- G21G4/04—Radioactive sources other than neutron sources
- G21G4/06—Radioactive sources other than neutron sources characterised by constructional features
- G21G4/08—Radioactive sources other than neutron sources characterised by constructional features specially adapted for medical application
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
- C01G31/00—Compounds of vanadium
- C01G31/02—Oxides
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
- C01G33/00—Compounds of niobium
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
- C01G35/00—Compounds of tantalum
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
- G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
- G21G1/04—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes outside nuclear reactors or particle accelerators
- G21G1/10—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes outside nuclear reactors or particle accelerators by bombardment with electrically charged particles
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
- G21G4/00—Radioactive sources
- G21G4/04—Radioactive sources other than neutron sources
- G21G4/10—Radioactive sources other than neutron sources with radium emanation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
- G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
- G21G1/001—Recovery of specific isotopes from irradiated targets
- G21G2001/0021—Gallium
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
- G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
- G21G1/001—Recovery of specific isotopes from irradiated targets
- G21G2001/0094—Other isotopes not provided for in the groups listed above
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- High Energy & Nuclear Physics (AREA)
- Inorganic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Silicates, Zeolites, And Molecular Sieves (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nuclear Medicine (AREA)
Abstract
a presente invenção refere-se a um gerador de ge68/ga68 para a produção contínua de um nuclídeo-filho de ga68, em que o nuclídeo-pai de ge68 do mesmo é especificamente adsorvido em um material de suporte inorgânico e em que o dito nuclídeo-pai de ge68 decai continuamente para ga68 pela captura de elétrons a uma meia-vida de 270,82 d, em que o material de suporte inorgânico é pelo menos um óxido de metal que é selecionado do grupo que consiste de: vanádio, nióbio e tântalo. a invenção também se refere ao uso de pelo menos um óxido de metal que é selecionado do grupo que consiste em: vanádio, nióbio e tântalo como material de suporte inorgânico para a fabricação de um gerador de ge68/ga68 para finalidades farmacêuticas. com o material de suporte inorgânico da presente invenção, é possível carregar os geradores de ge68/ga68 com até 8.000 mbq de ge68 (o que corresponde a 80 µg de germânio).
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16206969.4 | 2016-12-27 | ||
| EP16206969.4A EP3343570B1 (en) | 2016-12-27 | 2016-12-27 | 68ge/68ga generator |
| PCT/EP2017/084627 WO2018122250A1 (en) | 2016-12-27 | 2017-12-27 | 68ge/68ga generator |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112018077045A2 true BR112018077045A2 (pt) | 2019-04-02 |
| BR112018077045B1 BR112018077045B1 (pt) | 2023-02-23 |
Family
ID=57681441
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112018077045-0A BR112018077045B1 (pt) | 2016-12-27 | 2017-12-27 | Gerador de ge68/ga68 e uso de pelo menos um óxido de metal que é selecionado do grupo |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US10943709B2 (pt) |
| EP (1) | EP3343570B1 (pt) |
| JP (1) | JP6691333B2 (pt) |
| CN (1) | CN109564788B (pt) |
| AU (1) | AU2017387709B2 (pt) |
| BR (1) | BR112018077045B1 (pt) |
| CA (1) | CA3008953C (pt) |
| DK (1) | DK3343570T3 (pt) |
| HU (1) | HUE046302T2 (pt) |
| PL (1) | PL3343570T3 (pt) |
| SI (1) | SI3343570T1 (pt) |
| WO (1) | WO2018122250A1 (pt) |
| ZA (1) | ZA201904084B (pt) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102021109246B3 (de) | 2021-04-13 | 2022-06-09 | ITM Isotope Technologies Munich SE | Radiopharmaka zu unterschiedlichen ARTs |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1452185A1 (en) * | 2003-02-28 | 2004-09-01 | Euratom | Activation and production of radiolabeled particles |
| DE102004057225B4 (de) * | 2004-11-26 | 2006-10-12 | Johannes-Gutenberg-Universität Mainz | Verfahren und Vorrichtung zur Isolierung eines chemisch und radiochemisch gereinigten 68Ga-Radionuklids und zum Markieren eines Markierungsvorläufers mit dem 68Ga-Radionuklid |
| WO2008108311A1 (ja) * | 2007-03-02 | 2008-09-12 | Nagasaki University | Ｇｅ吸着剤 |
| WO2009102378A2 (en) * | 2007-12-03 | 2009-08-20 | Ge Healthcare Limited | Purification of 68ge/68ga generator eluate from fe(iii) intended to improve specific radioactivity of 68ga-based radiopharmaceuticals |
| DE102009007799B4 (de) * | 2009-02-06 | 2010-10-14 | ITM Isotopen Technologien München AG | Molekül zur Funktionalisierung eines Trägers, Bindung eines Radionuklids an den Träger und Radionuklidgenerator zur Herstellung des Radionuklids sowie Herstellungsverfahren |
| DE102009049108B4 (de) | 2009-10-12 | 2016-12-08 | Johannes Gutenberg-Universität Mainz | Verfahren und Vorrichtung zur Gewinnung eines Radionuklids |
| CN101777399B (zh) * | 2010-02-03 | 2012-07-25 | 原子高科股份有限公司 | 一种用于PET衰减校正的68Ge线源的制备工艺 |
| DE102010037964B3 (de) | 2010-10-05 | 2012-03-22 | ITM Isotopen Technologien München AG | 68Ga-Generator |
| CN102382994B (zh) * | 2011-07-18 | 2013-08-14 | 原子高科股份有限公司 | 一种放射性68Ge溶液的制备方法 |
| TWI451444B (zh) * | 2011-09-01 | 2014-09-01 | Germanium -68 / gallium-68 radioactive nuclear species generator device | |
| WO2013082699A1 (en) * | 2011-12-08 | 2013-06-13 | Nordion (Canada) Inc. | Method of pre-treating an adsorbent for a chromatographic separation |
| KR101646601B1 (ko) * | 2015-06-30 | 2016-08-10 | 한국원자력연구원 | 이종 금속이 도핑된 티탄 복합 산화물 제조 방법, 및 이에 의하여 제조된 이종 금속이 도핑된 티탄 복합 산화물 |
-
2016
- 2016-12-27 PL PL16206969T patent/PL3343570T3/pl unknown
- 2016-12-27 HU HUE16206969A patent/HUE046302T2/hu unknown
- 2016-12-27 SI SI201630363T patent/SI3343570T1/sl unknown
- 2016-12-27 EP EP16206969.4A patent/EP3343570B1/en active Active
- 2016-12-27 DK DK16206969.4T patent/DK3343570T3/da active
-
2017
- 2017-12-27 JP JP2018568218A patent/JP6691333B2/ja active Active
- 2017-12-27 CA CA3008953A patent/CA3008953C/en active Active
- 2017-12-27 BR BR112018077045-0A patent/BR112018077045B1/pt active IP Right Grant
- 2017-12-27 AU AU2017387709A patent/AU2017387709B2/en active Active
- 2017-12-27 US US16/073,973 patent/US10943709B2/en active Active
- 2017-12-27 CN CN201780049465.8A patent/CN109564788B/zh active Active
- 2017-12-27 WO PCT/EP2017/084627 patent/WO2018122250A1/en active Application Filing
-
2019
- 2019-06-24 ZA ZA2019/04084A patent/ZA201904084B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP6691333B2 (ja) | 2020-04-28 |
| HUE046302T2 (hu) | 2020-02-28 |
| DK3343570T3 (da) | 2019-09-23 |
| CA3008953C (en) | 2020-05-12 |
| CN109564788B (zh) | 2023-09-08 |
| ZA201904084B (en) | 2021-04-28 |
| CA3008953A1 (en) | 2018-06-27 |
| US20190066860A1 (en) | 2019-02-28 |
| US10943709B2 (en) | 2021-03-09 |
| JP2019527347A (ja) | 2019-09-26 |
| SI3343570T1 (sl) | 2019-10-30 |
| WO2018122250A1 (en) | 2018-07-05 |
| CN109564788A (zh) | 2019-04-02 |
| AU2017387709B2 (en) | 2019-01-24 |
| EP3343570A1 (en) | 2018-07-04 |
| EP3343570B1 (en) | 2019-07-03 |
| AU2017387709A1 (en) | 2018-08-02 |
| PL3343570T3 (pl) | 2019-11-29 |
| BR112018077045B1 (pt) | 2023-02-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
| B25A | Requested transfer of rights approved |
Owner name: ITM ISOTOPE TECHNOLOGIES MUNICH SE (DE) |
|
| B06W | Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 27/12/2017, OBSERVADAS AS CONDICOES LEGAIS |