BR112018013645A2 - processo para concentrar soluções de biomolécula - Google Patents

processo para concentrar soluções de biomolécula

Info

Publication number
BR112018013645A2
BR112018013645A2 BR112018013645A BR112018013645A BR112018013645A2 BR 112018013645 A2 BR112018013645 A2 BR 112018013645A2 BR 112018013645 A BR112018013645 A BR 112018013645A BR 112018013645 A BR112018013645 A BR 112018013645A BR 112018013645 A2 BR112018013645 A2 BR 112018013645A2
Authority
BR
Brazil
Prior art keywords
concentrating
pressure
biomolecule
biomolecule solutions
liquid
Prior art date
Application number
BR112018013645A
Other languages
English (en)
Inventor
Heise Charles
Nagy Tibor
Original Assignee
Fujifilm Diosynth Biotechnologies Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujifilm Diosynth Biotechnologies Uk Ltd filed Critical Fujifilm Diosynth Biotechnologies Uk Ltd
Publication of BR112018013645A2 publication Critical patent/BR112018013645A2/pt

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/20—Accessories; Auxiliary operations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/02—Hollow fibre modules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Water Supply & Treatment (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Prostheses (AREA)

Abstract

método de concentração de um líquido compreendendo uma biomolécula é fornecido. o método compreende passar o líquido através de um dispositivo de filtração de fluxo tangencial sob pressão, em que a pressão aplicada é variada entre pelo menos uma pressão mais alta e uma pressão mais baixa. preferivelmente, a variação na pressão é distribuída pelo uso de um controlador de fluxo variável, tal como uma válvula.
BR112018013645A 2016-01-07 2016-12-19 processo para concentrar soluções de biomolécula BR112018013645A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1600287.5A GB201600287D0 (en) 2016-01-07 2016-01-07 Process
PCT/GB2016/053980 WO2017118835A1 (en) 2016-01-07 2016-12-19 Tangential flow filtration process for concentrating biomolecule solutions

Publications (1)

Publication Number Publication Date
BR112018013645A2 true BR112018013645A2 (pt) 2019-01-22

Family

ID=55445681

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018013645A BR112018013645A2 (pt) 2016-01-07 2016-12-19 processo para concentrar soluções de biomolécula

Country Status (13)

Country Link
US (2) US10934325B2 (pt)
EP (1) EP3400234A1 (pt)
JP (1) JP6951341B2 (pt)
KR (1) KR20180100206A (pt)
CN (2) CN116874554A (pt)
AU (1) AU2016384285B2 (pt)
BR (1) BR112018013645A2 (pt)
CA (1) CA3010431A1 (pt)
GB (1) GB201600287D0 (pt)
RU (1) RU2754855C2 (pt)
SG (1) SG11201805687UA (pt)
WO (1) WO2017118835A1 (pt)
ZA (1) ZA201804527B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201600287D0 (en) * 2016-01-07 2016-02-24 Fujifilm Diosynth Biotechnologies Uk Ltd Process
GB201802593D0 (en) 2018-02-16 2018-04-04 Fujifilm Diosynth Biotechnologies Uk Ltd Rig
WO2019236811A1 (en) * 2018-06-08 2019-12-12 Bristol-Myers Squibb Company Single pass tangential flow filtration hybrid configurations for enhancing concentration of macromolecule solutions
GB201818709D0 (en) 2018-11-16 2019-01-02 Fujifilm Diosynth Biotechnologies Uk Ltd Mixer
GB201911685D0 (en) 2019-08-15 2019-10-02 Fujifilm Diosynth Biotechnologies Uk Ltd Process for purifying monoclonal antibodies
GB201911687D0 (en) 2019-08-15 2019-10-02 Fujifilm Diosynth Biotechnologies Uk Ltd Apparatus for purifying a liquid comprising a target substance
GB201911686D0 (en) 2019-08-15 2019-10-02 Fujifilm Diosynth Biotechnologies Uk Ltd Process for purifying target substances

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US3951377A (en) * 1974-11-07 1976-04-20 The United States Of America As Represented By The Secretary Of The Navy Rolling-gate, quiet-throttling, flow-control valve
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EP0079040A3 (en) * 1981-11-06 1984-12-27 Hydronautics, Incorporated Method and apparatus for increasing the cross-flow filtration fluxes of liquids containing suspended solids
JPS58190447A (ja) * 1982-04-30 1983-11-07 株式会社クラレ 脈動発生装置
JPS6443305A (en) * 1987-08-10 1989-02-15 Fuji Photo Film Co Ltd Cross flow type filtration process
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EP3235557A1 (en) * 2011-09-01 2017-10-25 Chugai Seiyaku Kabushiki Kaisha Method for preparing a composition comprising highly concentrated antibodies by ultrafiltration
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GB201600287D0 (en) * 2016-01-07 2016-02-24 Fujifilm Diosynth Biotechnologies Uk Ltd Process

Also Published As

Publication number Publication date
WO2017118835A1 (en) 2017-07-13
CN108779145A (zh) 2018-11-09
CA3010431A1 (en) 2017-07-13
ZA201804527B (en) 2023-12-20
US20210163530A1 (en) 2021-06-03
RU2018128566A (ru) 2020-02-07
AU2016384285A1 (en) 2018-07-19
RU2754855C2 (ru) 2021-09-08
AU2016384285B2 (en) 2023-11-02
US10934325B2 (en) 2021-03-02
CN108779145B (zh) 2023-06-13
SG11201805687UA (en) 2018-07-30
KR20180100206A (ko) 2018-09-07
JP2019505514A (ja) 2019-02-28
US11685765B2 (en) 2023-06-27
GB201600287D0 (en) 2016-02-24
JP6951341B2 (ja) 2021-10-20
EP3400234A1 (en) 2018-11-14
RU2018128566A3 (pt) 2020-03-27
US20190010189A1 (en) 2019-01-10
CN116874554A (zh) 2023-10-13

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Legal Events

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B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B154 Notification of filing of divisional application [chapter 15.50 patent gazette]

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