BR112018013592A2 - composições tópicas de ciclosporina a - Google Patents
composições tópicas de ciclosporina aInfo
- Publication number
- BR112018013592A2 BR112018013592A2 BR112018013592A BR112018013592A BR112018013592A2 BR 112018013592 A2 BR112018013592 A2 BR 112018013592A2 BR 112018013592 A BR112018013592 A BR 112018013592A BR 112018013592 A BR112018013592 A BR 112018013592A BR 112018013592 A2 BR112018013592 A2 BR 112018013592A2
- Authority
- BR
- Brazil
- Prior art keywords
- cyclosporine
- topical compositions
- relates
- compositions
- pvm
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Dispersion Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Pulmonology (AREA)
- Biochemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
Abstract
a presente invenção se refere a microemulsões farmacêuticas tópicas de ciclosporina a compreendendo uma metade de alquil ésteres (c1-c4) de copolímeros poli (anidrido metil vinil éter-co-maleico) (pvm / ma). a invenção também se refere a um processo para o preparo das referidas composições e ao seu uso na prevenção e / ou tratamento de diversas doenças, particularmente psoríase e dermatite atópica.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP16382001.2A EP3187172A1 (en) | 2016-01-04 | 2016-01-04 | Cyclosporine a topical compositions |
PCT/EP2017/050059 WO2017118622A1 (en) | 2016-01-04 | 2017-01-03 | Cyclosporine a topical compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112018013592A2 true BR112018013592A2 (pt) | 2019-01-08 |
Family
ID=55177914
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112018013592A BR112018013592A2 (pt) | 2016-01-04 | 2017-01-03 | composições tópicas de ciclosporina a |
Country Status (11)
Country | Link |
---|---|
US (1) | US20190022174A1 (pt) |
EP (2) | EP3187172A1 (pt) |
JP (1) | JP2019504878A (pt) |
KR (1) | KR20180100596A (pt) |
CN (1) | CN108472254A (pt) |
AU (1) | AU2017205249A1 (pt) |
BR (1) | BR112018013592A2 (pt) |
CA (1) | CA3009746A1 (pt) |
MX (1) | MX2018008109A (pt) |
RU (1) | RU2018123153A (pt) |
WO (1) | WO2017118622A1 (pt) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2019002362A1 (en) * | 2017-06-28 | 2019-01-03 | Spherium Biomed, S.L. | TOPICAL COMPOSITIONS OF CYCLOSPORIN A |
WO2020047205A1 (en) * | 2018-08-31 | 2020-03-05 | Arctic Therapeutics, Llc | Novel topical formulation for intradermal application and uses thereof |
GB201904757D0 (en) * | 2019-04-04 | 2019-05-22 | Biorelevant Com Ltd | Biorelevant composition |
CN113350484A (zh) * | 2021-04-21 | 2021-09-07 | 珠海欧维斯科技有限公司 | 一种毛囊再生复合物的研发制备及应用 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2222770B (en) * | 1988-09-16 | 1992-07-29 | Sandoz Ltd | Pharmaceutical compositions containing cyclosporins |
US5891846A (en) | 1994-02-17 | 1999-04-06 | Shiseido Company, Ltd. | Cyclosporin-containing emulsion composition |
WO2001028518A1 (de) * | 1999-10-20 | 2001-04-26 | Vesifact Ag | Cyclosporine enthaltende mikroemulsion-prekonzentrate und mikroemulsionen |
US20050059583A1 (en) | 2003-09-15 | 2005-03-17 | Allergan, Inc. | Methods of providing therapeutic effects using cyclosporin components |
US20070015691A1 (en) * | 2005-07-13 | 2007-01-18 | Allergan, Inc. | Cyclosporin compositions |
KR101492447B1 (ko) * | 2013-05-20 | 2015-02-23 | 주식회사태준제약 | 사이클로스포린을 함유하는 나노에멀젼 점안 조성물 및 그의 제조 방법 |
-
2016
- 2016-01-04 EP EP16382001.2A patent/EP3187172A1/en not_active Withdrawn
-
2017
- 2017-01-03 KR KR1020187021717A patent/KR20180100596A/ko unknown
- 2017-01-03 EP EP17700019.7A patent/EP3399964A1/en not_active Withdrawn
- 2017-01-03 CN CN201780005744.4A patent/CN108472254A/zh active Pending
- 2017-01-03 RU RU2018123153A patent/RU2018123153A/ru not_active Application Discontinuation
- 2017-01-03 MX MX2018008109A patent/MX2018008109A/es unknown
- 2017-01-03 CA CA3009746A patent/CA3009746A1/en not_active Abandoned
- 2017-01-03 WO PCT/EP2017/050059 patent/WO2017118622A1/en active Application Filing
- 2017-01-03 US US16/068,276 patent/US20190022174A1/en not_active Abandoned
- 2017-01-03 BR BR112018013592A patent/BR112018013592A2/pt not_active Application Discontinuation
- 2017-01-03 JP JP2018553313A patent/JP2019504878A/ja active Pending
- 2017-01-03 AU AU2017205249A patent/AU2017205249A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU2017205249A1 (en) | 2018-07-12 |
KR20180100596A (ko) | 2018-09-11 |
US20190022174A1 (en) | 2019-01-24 |
JP2019504878A (ja) | 2019-02-21 |
CN108472254A (zh) | 2018-08-31 |
CA3009746A1 (en) | 2017-07-13 |
EP3399964A1 (en) | 2018-11-14 |
MX2018008109A (es) | 2018-11-29 |
EP3187172A1 (en) | 2017-07-05 |
RU2018123153A (ru) | 2020-02-06 |
WO2017118622A1 (en) | 2017-07-13 |
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Legal Events
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B350 | Update of information on the portal [chapter 15.35 patent gazette] |