BR112018012747A2 - instrumento eletrocirúrgico com múltiplas modalidades de tratamento - Google Patents
instrumento eletrocirúrgico com múltiplas modalidades de tratamentoInfo
- Publication number
- BR112018012747A2 BR112018012747A2 BR112018012747A BR112018012747A BR112018012747A2 BR 112018012747 A2 BR112018012747 A2 BR 112018012747A2 BR 112018012747 A BR112018012747 A BR 112018012747A BR 112018012747 A BR112018012747 A BR 112018012747A BR 112018012747 A2 BR112018012747 A2 BR 112018012747A2
- Authority
- BR
- Brazil
- Prior art keywords
- electrosurgical instrument
- bleeding
- treatment modalities
- multiple treatment
- vessel
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/042—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating using additional gas becoming plasma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B18/1477—Needle-like probes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B18/1482—Probes or electrodes therefor having a long rigid shaft for accessing the inner body transcutaneously in minimal invasive surgery, e.g. laparoscopy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/1815—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
- A61B2018/00011—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
- A61B2018/00029—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids open
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00059—Material properties
- A61B2018/00071—Electrical conductivity
- A61B2018/00077—Electrical conductivity high, i.e. electrically conducting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00107—Coatings on the energy applicator
- A61B2018/00113—Coatings on the energy applicator with foam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00166—Multiple lumina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
- A61B2018/00577—Ablation
- A61B2018/00583—Coblation, i.e. ablation using a cold plasma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
- A61B2018/00589—Coagulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00696—Controlled or regulated parameters
- A61B2018/00702—Power or energy
- A61B2018/00708—Power or energy switching the power on or off
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00875—Resistance or impedance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00994—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body combining two or more different kinds of non-mechanical energy or combining one or more non-mechanical energies with ultrasound
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B2018/1405—Electrodes having a specific shape
- A61B2018/1435—Spiral
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/1815—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
- A61B2018/183—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves characterised by the type of antenna
- A61B2018/1846—Helical antennas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/1815—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
- A61B2018/1861—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves with an instrument inserted into a body lumen or cavity, e.g. a catheter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/1815—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
- A61B2018/1869—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves with an instrument interstitially inserted into the body, e.g. needles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/1815—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
- A61B2018/1892—Details of electrical isolations of the antenna
Landscapes
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physics & Mathematics (AREA)
- Otolaryngology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Plasma & Fusion (AREA)
- Electromagnetism (AREA)
- Surgical Instruments (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
um instrumento eletrocirúrgico que é capaz de operação seletiva em qualquer um dentre (i) um modo de geração de plasma para coagulação superficial, (ii) um modo de radiação não ionizante para coagulação mais profunda, por exemplo, usando energia de micro-ondas, e (iii) um modo de administração de líquido para transportar o líquido até um local de tratamento, por exemplo, para contrair um vaso em hemorragia de modo que um médico possa ter o controle da hemorragia. esses modos de operação podem ser fornecidos em um instrumento eletrocirúrgico que é fisicamente configurado para ser adequado para a aplicação de pressão a um vaso tecidual, por exemplo, para agir como um tamponante para estancar a hemorragia.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1603744.2A GB2547941A (en) | 2016-03-04 | 2016-03-04 | Electrosurgical instrument |
PCT/EP2017/054899 WO2017149072A2 (en) | 2016-03-04 | 2017-03-02 | Electrosurgical instrument having multiple treatment modalities |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112018012747A2 true BR112018012747A2 (pt) | 2018-12-04 |
Family
ID=55858989
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112018012747A BR112018012747A2 (pt) | 2016-03-04 | 2017-03-02 | instrumento eletrocirúrgico com múltiplas modalidades de tratamento |
Country Status (15)
Country | Link |
---|---|
US (1) | US10820937B2 (pt) |
EP (1) | EP3422981B1 (pt) |
JP (1) | JP6960165B2 (pt) |
KR (1) | KR102414547B1 (pt) |
CN (1) | CN108697464B (pt) |
AU (1) | AU2017228015B2 (pt) |
BR (1) | BR112018012747A2 (pt) |
CA (1) | CA3008347A1 (pt) |
DK (1) | DK3422981T3 (pt) |
ES (1) | ES2779801T3 (pt) |
GB (1) | GB2547941A (pt) |
PT (1) | PT3422981T (pt) |
SG (1) | SG11201805321YA (pt) |
WO (1) | WO2017149072A2 (pt) |
ZA (1) | ZA201803424B (pt) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB201308558D0 (en) * | 2013-05-13 | 2013-06-19 | Creo Medical Ltd | Electrosurgical apparatus |
GB2550414A (en) * | 2016-05-20 | 2017-11-22 | Creo Medical Ltd | Antenna structure |
GB2559604A (en) * | 2017-02-13 | 2018-08-15 | Creo Medical Ltd | Microwave energy transfer component for electrosurgical apparatus |
GB2563377A (en) * | 2017-05-04 | 2018-12-19 | Creo Medical Ltd | Electrosurgical apparatus and method of tissue ablation |
GB2562110A (en) * | 2017-05-05 | 2018-11-07 | Creo Medical Ltd | Apparatus for sterilising an instrument channel of a surgical scoping device |
GB2563203A (en) * | 2017-06-01 | 2018-12-12 | Creo Medical Ltd | Electrosurgical apparatus |
CN109953815A (zh) * | 2017-12-25 | 2019-07-02 | 四川锦江电子科技有限公司 | 一种多极等离子消融导管管体 |
CN109953816A (zh) * | 2017-12-25 | 2019-07-02 | 四川锦江电子科技有限公司 | 一种多极等离子消融装置 |
CN109953819A (zh) * | 2017-12-25 | 2019-07-02 | 四川锦江电子科技有限公司 | 一种多极等离子消融导管 |
WO2019161284A1 (en) * | 2018-02-16 | 2019-08-22 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Ionizing radiation-free dental imaging by near-infrared fluorescence, and related systems |
US11197708B2 (en) | 2018-02-28 | 2021-12-14 | Gyrus Acmi, Inc. | Plasma generator configured for use with an auxiliary device |
GB2574365A (en) * | 2018-03-16 | 2019-12-11 | Creo Medical Ltd | Sterilization apparatus |
GB2576477B (en) * | 2018-05-01 | 2022-02-16 | Creo Medical Ltd | Apparatus for treating urinary tract infections |
GB2573823A (en) * | 2018-05-19 | 2019-11-20 | Creo Medical Ltd | Electrosurgical ablation instrument |
GB2574219A (en) * | 2018-05-30 | 2019-12-04 | Creo Medical Ltd | Electrosurgical instrument |
GB2577706A (en) * | 2018-10-03 | 2020-04-08 | Creo Medical Ltd | Electrosurgical instrument |
GB2579644A (en) * | 2018-12-10 | 2020-07-01 | Creo Medical Ltd | A modular electrosurgical system, and modules for said system |
EP3695798A1 (en) * | 2019-02-13 | 2020-08-19 | National University of Ireland Galway | An ablation probe |
JP7418141B2 (ja) * | 2019-06-04 | 2024-01-19 | 日本特殊陶業株式会社 | プラズマ照射装置及び先端デバイス |
KR102049483B1 (ko) * | 2019-08-07 | 2019-11-27 | 주식회사 울트라브이 | 범용 전기 수술기 |
GB2589589A (en) * | 2019-12-03 | 2021-06-09 | Creo Medical Ltd | Electrosurgical instrument |
GB2590424A (en) * | 2019-12-17 | 2021-06-30 | Creo Medical Ltd | Electrosurgical instrument and apparatus |
EP4120943B1 (en) * | 2020-03-19 | 2024-06-12 | Caps Medical Ltd. | Treatment of internal spaces using plasma generating device |
US20230126911A1 (en) * | 2020-03-19 | 2023-04-27 | Caps Medical Ltd. | Plasma system with a plurality of plasma generating sites |
CN111772776A (zh) * | 2020-07-16 | 2020-10-16 | 嘉兴市第二医院 | 一种射频与化学一体化消融装置 |
EP4329653A1 (fr) * | 2021-04-28 | 2024-03-06 | Sorbonne Universite | Outil pour dispositif de traitement medical par plasma et dispositif correspondant |
WO2022240233A1 (ko) * | 2021-05-13 | 2022-11-17 | 서석배 | Rf 전류 및 플라즈마 기반의 자극 제공 장치 |
CN114376722B (zh) * | 2022-03-24 | 2022-05-31 | 北京格瑞朗博科技发展有限公司 | 一种射频和低温等离子的手术电极 |
CN115778526B (zh) * | 2022-07-11 | 2023-08-29 | 南京康友医疗科技有限公司 | 一种微波、射频和测温一体式消融针 |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6787730B2 (en) * | 1998-07-09 | 2004-09-07 | Damian Coccio | Device for plasma incision of matter with a specifically tuned radiofrequency electromagnetic field generator |
US7276063B2 (en) * | 1998-08-11 | 2007-10-02 | Arthrocare Corporation | Instrument for electrosurgical tissue treatment |
US7311708B2 (en) * | 2001-12-12 | 2007-12-25 | Tissuelink Medical, Inc. | Fluid-assisted medical devices, systems and methods |
US6936048B2 (en) | 2003-01-16 | 2005-08-30 | Charlotte-Mecklenburg Hospital Authority | Echogenic needle for transvaginal ultrasound directed reduction of uterine fibroids and an associated method |
EP2320820B1 (en) * | 2008-05-16 | 2014-03-19 | Trod Medical | Percutaneous and laparoscopic surgical instrument |
JP4706725B2 (ja) | 2008-06-20 | 2011-06-22 | コニカミノルタビジネステクノロジーズ株式会社 | 定着装置および画像形成装置 |
US8968287B2 (en) * | 2008-10-21 | 2015-03-03 | Microcube, Llc | Methods and devices for applying energy to bodily tissues |
US20140358140A1 (en) * | 2008-10-21 | 2014-12-04 | Microcube, Llc | Microwave treatment devices and methods |
DE102009044512B4 (de) * | 2009-09-11 | 2021-08-12 | Erbe Elektromedizin Gmbh | Karbonisierungsverhinderungsvorrichtung |
GB2474058B (en) * | 2009-10-02 | 2014-10-01 | Creo Medical Ltd | Cosmetic Surgery Apparatus |
AU2010316657A1 (en) * | 2009-11-09 | 2012-06-21 | Ionmed Ltd | Plasma head for tissue welding |
JP5999778B2 (ja) * | 2010-10-26 | 2016-09-28 | エルベ エレクトロメディジン ゲゼルシャフト ミット ベシュレンクテル ハフツングERBE ELEKTROMEDIZIN GmbH | 止血器具 |
US9011421B2 (en) * | 2011-01-05 | 2015-04-21 | Covidien Lp | Energy-delivery devices with flexible fluid-cooled shaft, inflow/outflow junctions suitable for use with same, and systems including same |
GB2487199A (en) * | 2011-01-11 | 2012-07-18 | Creo Medical Ltd | Electrosurgical device with fluid conduit |
EP4039208B1 (en) * | 2011-01-19 | 2023-08-30 | Fractyl Health, Inc. | Devices for the treatment of tissue |
CA2845795A1 (en) * | 2011-04-08 | 2013-07-18 | Covidien Lp | Flexible microwave catheters for natural or artificial lumens |
EP2755588B1 (en) * | 2011-09-14 | 2016-05-18 | Boston Scientific Scimed, Inc. | Ablation device with ionically conductive balloon |
GB2503673A (en) * | 2012-07-03 | 2014-01-08 | Creo Medical Ltd | Electrosurgical device with convex under surface |
GB201308558D0 (en) * | 2013-05-13 | 2013-06-19 | Creo Medical Ltd | Electrosurgical apparatus |
GB2521611B (en) | 2013-12-23 | 2020-02-12 | Creo Medical Ltd | Electrosurgical apparatus and electrosurgical device |
GB2548382B (en) * | 2016-03-16 | 2019-04-03 | Fourth State Medicine Ltd | Plasma generation |
-
2016
- 2016-03-04 GB GB1603744.2A patent/GB2547941A/en not_active Withdrawn
-
2017
- 2017-03-02 AU AU2017228015A patent/AU2017228015B2/en not_active Ceased
- 2017-03-02 JP JP2018533634A patent/JP6960165B2/ja active Active
- 2017-03-02 WO PCT/EP2017/054899 patent/WO2017149072A2/en active Application Filing
- 2017-03-02 SG SG11201805321YA patent/SG11201805321YA/en unknown
- 2017-03-02 PT PT177082609T patent/PT3422981T/pt unknown
- 2017-03-02 CA CA3008347A patent/CA3008347A1/en active Pending
- 2017-03-02 BR BR112018012747A patent/BR112018012747A2/pt not_active Application Discontinuation
- 2017-03-02 CN CN201780004647.3A patent/CN108697464B/zh active Active
- 2017-03-02 US US15/781,442 patent/US10820937B2/en active Active
- 2017-03-02 KR KR1020187018263A patent/KR102414547B1/ko active IP Right Grant
- 2017-03-02 ES ES17708260T patent/ES2779801T3/es active Active
- 2017-03-02 DK DK17708260.9T patent/DK3422981T3/da active
- 2017-03-02 EP EP17708260.9A patent/EP3422981B1/en active Active
-
2018
- 2018-05-23 ZA ZA2018/03424A patent/ZA201803424B/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2017149072A2 (en) | 2017-09-08 |
CN108697464B (zh) | 2020-11-20 |
EP3422981A2 (en) | 2019-01-09 |
KR102414547B1 (ko) | 2022-06-29 |
SG11201805321YA (en) | 2018-07-30 |
PT3422981T (pt) | 2020-03-26 |
US20190083159A1 (en) | 2019-03-21 |
AU2017228015B2 (en) | 2021-05-13 |
AU2017228015A1 (en) | 2018-06-14 |
CA3008347A1 (en) | 2017-09-08 |
GB2547941A (en) | 2017-09-06 |
KR20180123005A (ko) | 2018-11-14 |
GB201603744D0 (en) | 2016-04-20 |
US10820937B2 (en) | 2020-11-03 |
WO2017149072A3 (en) | 2017-10-12 |
DK3422981T3 (da) | 2020-04-20 |
ZA201803424B (en) | 2019-08-28 |
CN108697464A (zh) | 2018-10-23 |
ES2779801T3 (es) | 2020-08-19 |
EP3422981B1 (en) | 2020-02-05 |
JP2019509077A (ja) | 2019-04-04 |
JP6960165B2 (ja) | 2021-11-05 |
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