BR112018008527A2 - composição de vacina contra neospora - Google Patents
composição de vacina contra neosporaInfo
- Publication number
- BR112018008527A2 BR112018008527A2 BR112018008527A BR112018008527A BR112018008527A2 BR 112018008527 A2 BR112018008527 A2 BR 112018008527A2 BR 112018008527 A BR112018008527 A BR 112018008527A BR 112018008527 A BR112018008527 A BR 112018008527A BR 112018008527 A2 BR112018008527 A2 BR 112018008527A2
- Authority
- BR
- Brazil
- Prior art keywords
- protein
- present
- compositions
- vaccine composition
- methods
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 241001147660 Neospora Species 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 abstract 6
- 108090000623 proteins and genes Proteins 0.000 abstract 6
- 238000000034 method Methods 0.000 abstract 2
- 241001147662 Neospora caninum Species 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 238000004811 liquid chromatography Methods 0.000 abstract 1
- 238000001294 liquid chromatography-tandem mass spectrometry Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 210000000059 tachyzoite Anatomy 0.000 abstract 1
- 238000004885 tandem mass spectrometry Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/002—Protozoa antigens
- A61K39/012—Coccidia antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/002—Protozoa antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/10—Protozoa; Culture media therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Virology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
Abstract
a presente invenção se refere a novas composições de proteína, métodos para produzir as ditas composições de proteína, composições farmacêuticas que compreendem as ditas composições de proteína e métodos para o tratamento de infecções causadas por neospora caninum. em particular, a presente invenção se refere a uma composição de proteína que compreende as proteínas especificadas na tabela a em uma quantidade de pelo menos cerca de 2 vezes ("fold change") maior do que a mesma proteína presente na taquizoíta integral, conforme calculado por meio de cromatografia de líquido - espectrometria de massa em tandem quantitativa sem marcador (lc-ms/ms).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15382532 | 2015-10-28 | ||
| PCT/EP2016/076137 WO2017072325A1 (en) | 2015-10-28 | 2016-10-28 | Neospora vaccine composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112018008527A2 true BR112018008527A2 (pt) | 2018-11-06 |
Family
ID=54427686
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112018008527A BR112018008527A2 (pt) | 2015-10-28 | 2016-10-28 | composição de vacina contra neospora |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US10864260B2 (pt) |
| EP (1) | EP3368070B9 (pt) |
| AU (1) | AU2016347636B2 (pt) |
| BR (1) | BR112018008527A2 (pt) |
| CA (1) | CA3003343A1 (pt) |
| CL (1) | CL2018001130A1 (pt) |
| CO (1) | CO2018004630A2 (pt) |
| ES (1) | ES2960032T3 (pt) |
| IL (1) | IL258976B (pt) |
| MX (1) | MX2018005254A (pt) |
| NZ (1) | NZ742210A (pt) |
| WO (1) | WO2017072325A1 (pt) |
| ZA (1) | ZA201803039B (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110183527B (zh) * | 2019-05-21 | 2021-03-12 | 中国农业大学 | 一种新孢子虫NcMIC26抗原及其应用 |
| CN116284316B (zh) * | 2023-01-17 | 2023-12-29 | 西湖大学 | 一种针对原肌球蛋白受体激酶a的d5结构域的d-蛋白抑制剂及其应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5240704A (en) * | 1983-07-03 | 1993-08-31 | Kitasato Kenkyusho | Vaccine, antibodies & antibody-containing compositions for inhibiting human dental caries induced by streptococcus mutans |
| US5707617A (en) | 1994-03-21 | 1998-01-13 | The Regents Of The University Of California | Bovine neospora isolates |
| ATE271122T1 (de) | 1996-11-12 | 2004-07-15 | Pfizer | Attenuierter lebender neospora impfstoff |
| BR9803232A (pt) * | 1997-08-26 | 2000-01-11 | Pfizer Prod Inc | Vaicna de neospora. |
| ES2281936T3 (es) | 1997-10-20 | 2007-10-01 | Bayer Corporation | Vacuna contra neospora. |
| WO2004026903A2 (en) | 2002-09-20 | 2004-04-01 | Akzo Nobel N.V. | Live antenuated parasite vaccine |
| CR6773A (es) | 2002-10-08 | 2006-05-30 | Wyeth Corp | Vacuna contra la myeloencephalitis protozoal equina |
| US7887818B2 (en) | 2008-02-20 | 2011-02-15 | The United States Of America As Represented By The Secretary Of Agriculture | Neospora caninum vaccine |
-
2016
- 2016-10-28 AU AU2016347636A patent/AU2016347636B2/en active Active
- 2016-10-28 ES ES16795246T patent/ES2960032T3/es active Active
- 2016-10-28 MX MX2018005254A patent/MX2018005254A/es unknown
- 2016-10-28 CA CA3003343A patent/CA3003343A1/en active Pending
- 2016-10-28 NZ NZ742210A patent/NZ742210A/en unknown
- 2016-10-28 IL IL258976A patent/IL258976B/en unknown
- 2016-10-28 BR BR112018008527A patent/BR112018008527A2/pt active Search and Examination
- 2016-10-28 WO PCT/EP2016/076137 patent/WO2017072325A1/en active Application Filing
- 2016-10-28 EP EP16795246.4A patent/EP3368070B9/en active Active
- 2016-10-28 US US15/771,832 patent/US10864260B2/en active Active
-
2018
- 2018-04-27 CL CL2018001130A patent/CL2018001130A1/es unknown
- 2018-04-30 CO CONC2018/0004630A patent/CO2018004630A2/es unknown
- 2018-05-09 ZA ZA2018/03039A patent/ZA201803039B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL258976A (en) | 2018-06-28 |
| CL2018001130A1 (es) | 2018-11-23 |
| US10864260B2 (en) | 2020-12-15 |
| AU2016347636B2 (en) | 2021-02-18 |
| AU2016347636A1 (en) | 2018-05-24 |
| EP3368070B1 (en) | 2023-08-30 |
| ZA201803039B (en) | 2022-01-26 |
| NZ742210A (en) | 2023-06-30 |
| IL258976B (en) | 2022-08-01 |
| CO2018004630A2 (es) | 2018-07-19 |
| EP3368070A1 (en) | 2018-09-05 |
| EP3368070C0 (en) | 2023-08-30 |
| MX2018005254A (es) | 2019-10-04 |
| CA3003343A1 (en) | 2017-05-04 |
| WO2017072325A1 (en) | 2017-05-04 |
| ES2960032T3 (es) | 2024-02-29 |
| US20180311332A1 (en) | 2018-11-01 |
| EP3368070B9 (en) | 2023-10-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] |