BR112018007731A2 - composição para tratamento de infertilidade em um indivíduo feminino - Google Patents
composição para tratamento de infertilidade em um indivíduo femininoInfo
- Publication number
- BR112018007731A2 BR112018007731A2 BR112018007731A BR112018007731A BR112018007731A2 BR 112018007731 A2 BR112018007731 A2 BR 112018007731A2 BR 112018007731 A BR112018007731 A BR 112018007731A BR 112018007731 A BR112018007731 A BR 112018007731A BR 112018007731 A2 BR112018007731 A2 BR 112018007731A2
- Authority
- BR
- Brazil
- Prior art keywords
- composition
- infertility
- female individual
- female
- hyaluronic acid
- Prior art date
Links
- 208000000509 infertility Diseases 0.000 title abstract 3
- 230000036512 infertility Effects 0.000 title abstract 3
- 231100000535 infertility Toxicity 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 abstract 2
- 229920002674 hyaluronan Polymers 0.000 abstract 2
- 229960003160 hyaluronic acid Drugs 0.000 abstract 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 abstract 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 102000008100 Human Serum Albumin Human genes 0.000 abstract 1
- 108091006905 Human Serum Albumin Proteins 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 abstract 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 abstract 1
- 239000011575 calcium Substances 0.000 abstract 1
- 229910052791 calcium Inorganic materials 0.000 abstract 1
- 229920003086 cellulose ether Polymers 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 150000002500 ions Chemical class 0.000 abstract 1
- 229960004194 lidocaine Drugs 0.000 abstract 1
- 239000003589 local anesthetic agent Substances 0.000 abstract 1
- 239000011777 magnesium Substances 0.000 abstract 1
- 229910052749 magnesium Inorganic materials 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000011591 potassium Substances 0.000 abstract 1
- 229910052700 potassium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Veterinary Medicine (AREA)
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- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
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- Gynecology & Obstetrics (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Vascular Medicine (AREA)
- Pulmonology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
uma composição farmacêutica para o tratamento da infertilidade em um indivíduo do sexo feminino consistindo substancialmente em anestésico local do tipo amida, tal como lidocaína, albumina humana, agente controlador da viscosidade selecionado de ácido hialurônico recombinante e combinação de ácido hialurônico recombinante e éter de celulose solúvel em água, opcionalmente citrato, glicose e/ou aminoácido, compreendendo opcionalmente um ou mais íons selecionados do grupo que consiste em sódio, potássio, magnésio, cálcio, acetato, cloreto, sulfato. é também revelado um método de tratamento de infertilidade por administração da composição a um indivíduo do sexo feminino que necessite disso.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE1500425-2 | 2015-10-23 | ||
SE1500425 | 2015-10-23 | ||
PCT/SE2016/000055 WO2017069672A1 (en) | 2015-10-23 | 2016-10-11 | Composition for treatment of infertility in a female subject |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112018007731A2 true BR112018007731A2 (pt) | 2018-10-23 |
BR112018007731B1 BR112018007731B1 (pt) | 2023-11-14 |
Family
ID=58558029
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112018007731-3A BR112018007731B1 (pt) | 2015-10-23 | 2016-10-11 | Composições para tratamento de infertilidade em uma paciente do sexo feminino |
Country Status (20)
Country | Link |
---|---|
US (1) | US11191839B2 (pt) |
EP (1) | EP3364959B1 (pt) |
JP (2) | JP7276806B2 (pt) |
CN (1) | CN108348488A (pt) |
AU (1) | AU2016340769B2 (pt) |
BR (1) | BR112018007731B1 (pt) |
CA (1) | CA3002515C (pt) |
CL (1) | CL2018001058A1 (pt) |
DK (1) | DK3364959T3 (pt) |
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JP3449738B2 (ja) * | 1991-07-10 | 2003-09-22 | 武田薬品工業株式会社 | 水溶性組成物 |
US5700485A (en) | 1992-09-10 | 1997-12-23 | Children's Medical Center Corporation | Prolonged nerve blockade by the combination of local anesthetic and glucocorticoid |
EP1158978B1 (en) * | 1997-02-15 | 2005-10-05 | Edelstam Inc. | Medicament against dysmenorrhoea and premenstrual syndrome comprising lidocaine |
US5977143A (en) * | 1997-02-15 | 1999-11-02 | Edelstam; Greta | Medicament against infertility which reduces phagocytosis of spermatozoa in women |
IL129951A0 (en) * | 1997-07-02 | 2000-02-29 | Euro Celtique Sa | Prolonged anesthesia in joints and body spaces |
US6762053B2 (en) | 2000-06-09 | 2004-07-13 | Vitrolife, Inc. | Mammalian gamete and embryo culture media and culture media supplements |
CN1847393A (zh) * | 2000-06-09 | 2006-10-18 | 维特罗莱夫公司 | 添加剂,制剂和培养基 |
FR2815035B1 (fr) | 2000-10-05 | 2003-03-07 | Commissariat Energie Atomique | Procede de coprecipitation d'actinides et procede de preparation d'oxydes mixtes d'actinides |
AUPR803501A0 (en) * | 2001-10-02 | 2001-10-25 | Xeno Trans Ltd | Gene transfer composition and method |
US7998579B2 (en) | 2002-08-12 | 2011-08-16 | Exxonmobil Chemical Patents Inc. | Polypropylene based fibers and nonwovens |
ES2354696T3 (es) | 2003-07-31 | 2011-03-17 | Toyo Boseki Kabushiki Kaisha | Planta que produce ácido hialurónico. |
JP2007174957A (ja) | 2005-12-27 | 2007-07-12 | Toyobo Co Ltd | ヒアルロン酸生産酵母 |
JP5561636B2 (ja) | 2009-03-03 | 2014-07-30 | 東洋紡株式会社 | 改良されたヒアルロン酸の製造方法 |
US20110280763A1 (en) * | 2010-05-17 | 2011-11-17 | Abbott Medical Optics Inc. | Light-activated disinfection system |
WO2011145993A1 (en) * | 2010-05-19 | 2011-11-24 | Isifer Ab | Treatment for reducing inflammation |
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CA3002515A1 (en) | 2017-04-27 |
PL3364959T3 (pl) | 2022-12-27 |
SG10201912767WA (en) | 2020-02-27 |
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IL258757B (en) | 2021-07-29 |
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SA518391400B1 (ar) | 2022-09-19 |
IL258757A (en) | 2018-06-28 |
US11191839B2 (en) | 2021-12-07 |
EP3364959A1 (en) | 2018-08-29 |
JP2021130688A (ja) | 2021-09-09 |
CA3002515C (en) | 2024-01-02 |
MX2018004958A (es) | 2019-03-28 |
MY196628A (en) | 2023-04-23 |
BR112018007731B1 (pt) | 2023-11-14 |
WO2017069672A1 (en) | 2017-04-27 |
CN108348488A (zh) | 2018-07-31 |
EA036687B1 (ru) | 2020-12-08 |
AU2016340769A1 (en) | 2018-04-19 |
AU2016340769B2 (en) | 2018-07-12 |
JP7276806B2 (ja) | 2023-05-18 |
KR20180066193A (ko) | 2018-06-18 |
CL2018001058A1 (es) | 2018-09-14 |
EP3364959B1 (en) | 2022-07-13 |
HUE061056T2 (hu) | 2023-05-28 |
US20190240338A1 (en) | 2019-08-08 |
EP3364959A4 (en) | 2019-05-22 |
EA201890714A1 (ru) | 2018-09-28 |
NZ740967A (en) | 2024-03-22 |
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