BR112018003107A2 - aparelho para estimular atividade neural em um nervo vago, método para tratar broncoconstrição, broncodilatador, forma de onda elétrica neuromodulatória, uso de um dispositivo de neuromodulação, e, sistema de neuromodulação - Google Patents

aparelho para estimular atividade neural em um nervo vago, método para tratar broncoconstrição, broncodilatador, forma de onda elétrica neuromodulatória, uso de um dispositivo de neuromodulação, e, sistema de neuromodulação

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Publication number
BR112018003107A2
BR112018003107A2 BR112018003107A BR112018003107A BR112018003107A2 BR 112018003107 A2 BR112018003107 A2 BR 112018003107A2 BR 112018003107 A BR112018003107 A BR 112018003107A BR 112018003107 A BR112018003107 A BR 112018003107A BR 112018003107 A2 BR112018003107 A2 BR 112018003107A2
Authority
BR
Brazil
Prior art keywords
vagus nerve
neural activity
neuromodulation
bronchodilator
electrical waveform
Prior art date
Application number
BR112018003107A
Other languages
English (en)
Portuguese (pt)
Inventor
E Hunsberger Gerald
K Kwong Kevin
John Carr Michael
Original Assignee
Galvani Bioelectronics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galvani Bioelectronics Ltd filed Critical Galvani Bioelectronics Ltd
Publication of BR112018003107A2 publication Critical patent/BR112018003107A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/205—Applying electric currents by contact electrodes continuous direct currents for promoting a biological process
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36053—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for vagal stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/0816—Measuring devices for examining respiratory frequency
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/087—Measuring breath flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/091—Measuring volume of inspired or expired gases, e.g. to determine lung capacity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14542—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring blood gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/388—Nerve conduction study, e.g. detecting action potential of peripheral nerves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4029—Detecting, measuring or recording for evaluating the nervous system for evaluating the peripheral nervous systems
    • A61B5/4035—Evaluating the autonomic nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36057—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for stimulating afferent nerves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/3611—Respiration control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36135—Control systems using physiological parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/36167—Timing, e.g. stimulation onset
    • A61N1/36171—Frequency

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pathology (AREA)
  • Pulmonology (AREA)
  • Physiology (AREA)
  • Optics & Photonics (AREA)
  • Electrotherapy Devices (AREA)
BR112018003107A 2015-08-21 2016-08-18 aparelho para estimular atividade neural em um nervo vago, método para tratar broncoconstrição, broncodilatador, forma de onda elétrica neuromodulatória, uso de um dispositivo de neuromodulação, e, sistema de neuromodulação BR112018003107A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562208057P 2015-08-21 2015-08-21
PCT/IB2016/054957 WO2017033101A1 (en) 2015-08-21 2016-08-18 Neuromodulation device

Publications (1)

Publication Number Publication Date
BR112018003107A2 true BR112018003107A2 (pt) 2018-09-25

Family

ID=56853696

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018003107A BR112018003107A2 (pt) 2015-08-21 2016-08-18 aparelho para estimular atividade neural em um nervo vago, método para tratar broncoconstrição, broncodilatador, forma de onda elétrica neuromodulatória, uso de um dispositivo de neuromodulação, e, sistema de neuromodulação

Country Status (11)

Country Link
US (2) US11878160B2 (enExample)
EP (2) EP4052756B1 (enExample)
JP (1) JP2018523542A (enExample)
KR (1) KR20180044941A (enExample)
CN (1) CN108367151A (enExample)
AU (1) AU2016310626A1 (enExample)
BR (1) BR112018003107A2 (enExample)
CA (1) CA2996252A1 (enExample)
ES (2) ES2982192T3 (enExample)
RU (1) RU2018105336A (enExample)
WO (1) WO2017033101A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11571574B2 (en) 2016-11-11 2023-02-07 Galvani Bioelectronics Limited Treatment of diseases mediated by thyroid and parathyroid hormones
CN109045468B (zh) * 2018-08-09 2022-05-24 西安科悦医疗技术有限公司 一种耳部迷走神经刺激系统及其装置
AU2021209435A1 (en) * 2020-01-23 2022-08-25 Saluda Medical Pty Ltd Neuromodulation of primary and/or postsynaptic neurons

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07501233A (ja) * 1991-08-09 1995-02-09 サイベロニクス，インク． 神経刺激による不安障害の治療
ATE489132T1 (de) * 2004-12-27 2010-12-15 The Feinstein Inst Medical Res Behandlung von entzündlichen erkrankungen durch elektrische stimulation des vagus-nervs
US8660647B2 (en) 2005-07-28 2014-02-25 Cyberonics, Inc. Stimulating cranial nerve to treat pulmonary disorder
US7747324B2 (en) * 2005-11-10 2010-06-29 Electrocore Llc Electrical stimulation treatment of bronchial constriction
US8812112B2 (en) * 2005-11-10 2014-08-19 ElectroCore, LLC Electrical treatment of bronchial constriction
US8874227B2 (en) * 2009-03-20 2014-10-28 ElectroCore, LLC Devices and methods for non-invasive capacitive electrical stimulation and their use for vagus nerve stimulation on the neck of a patient
US20100217347A1 (en) 2006-12-16 2010-08-26 Greatbatch, Inc. Neurostimulation for the treatment of pulmonary disorders
US8483831B1 (en) 2008-02-15 2013-07-09 Holaira, Inc. System and method for bronchial dilation
EP4166107A1 (en) * 2008-05-09 2023-04-19 Nuvaira, Inc. Systems, assemblies, and methods for treating a bronchial tree
US8843210B2 (en) * 2009-03-20 2014-09-23 ElectroCore, LLC Non-invasive vagal nerve stimulation to treat disorders
US20120302909A1 (en) * 2009-11-11 2012-11-29 Mayse Martin L Methods and systems for screening subjects
US9398933B2 (en) 2012-12-27 2016-07-26 Holaira, Inc. Methods for improving drug efficacy including a combination of drug administration and nerve modulation
JP2015008746A (ja) * 2013-06-26 2015-01-19 オリンパス株式会社 神経刺激装置、副作用予測装置および神経刺激装置の作動方法
US20150202444A1 (en) 2014-01-17 2015-07-23 Cardiac Pacemakers, Inc. Systems and methods for selective stimulation of nerve fibers in carotid sinus
US9737716B2 (en) * 2014-08-12 2017-08-22 Cyberonics, Inc. Vagus nerve and carotid baroreceptor stimulation system

Also Published As

Publication number Publication date
EP4052756B1 (en) 2024-05-15
CN108367151A (zh) 2018-08-03
AU2016310626A1 (en) 2018-03-08
US11878160B2 (en) 2024-01-23
US20180236224A1 (en) 2018-08-23
CA2996252A1 (en) 2017-03-02
JP2018523542A (ja) 2018-08-23
EP4052756A1 (en) 2022-09-07
EP3337556A1 (en) 2018-06-27
ES2914685T3 (es) 2022-06-15
WO2017033101A1 (en) 2017-03-02
US20240131327A1 (en) 2024-04-25
ES2982192T3 (es) 2024-10-15
EP3337556B1 (en) 2022-05-25
RU2018105336A (ru) 2019-09-23
KR20180044941A (ko) 2018-05-03

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Legal Events

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B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]