BR112018000383A2 - métodos para tratar hcv - Google Patents
métodos para tratar hcvInfo
- Publication number
- BR112018000383A2 BR112018000383A2 BR112018000383A BR112018000383A BR112018000383A2 BR 112018000383 A2 BR112018000383 A2 BR 112018000383A2 BR 112018000383 A BR112018000383 A BR 112018000383A BR 112018000383 A BR112018000383 A BR 112018000383A BR 112018000383 A2 BR112018000383 A2 BR 112018000383A2
- Authority
- BR
- Brazil
- Prior art keywords
- treatment
- hcv
- weeks
- methods
- compound
- Prior art date
Links
- 102000014150 Interferons Human genes 0.000 abstract 2
- 108010050904 Interferons Proteins 0.000 abstract 2
- 239000003443 antiviral agent Substances 0.000 abstract 2
- 229940079322 interferon Drugs 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- IWUCXVSUMQZMFG-AFCXAGJDSA-N Ribavirin Chemical compound N1=C(C(=O)N)N=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](CO)O1 IWUCXVSUMQZMFG-AFCXAGJDSA-N 0.000 abstract 1
- 229940125904 compound 1 Drugs 0.000 abstract 1
- 229940125782 compound 2 Drugs 0.000 abstract 1
- 229960000329 ribavirin Drugs 0.000 abstract 1
- HZCAHMRRMINHDJ-DBRKOABJSA-N ribavirin Natural products O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1N=CN=C1 HZCAHMRRMINHDJ-DBRKOABJSA-N 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F16/00—Information retrieval; Database structures therefor; File system structures therefor
- G06F16/20—Information retrieval; Database structures therefor; File system structures therefor of structured data, e.g. relational data
- G06F16/21—Design, administration or maintenance of databases
- G06F16/215—Improving data quality; Data cleansing, e.g. de-duplication, removing invalid entries or correcting typographical errors
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F16/00—Information retrieval; Database structures therefor; File system structures therefor
- G06F16/20—Information retrieval; Database structures therefor; File system structures therefor of structured data, e.g. relational data
- G06F16/23—Updating
- G06F16/2365—Ensuring data consistency and integrity
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F16/00—Information retrieval; Database structures therefor; File system structures therefor
- G06F16/20—Information retrieval; Database structures therefor; File system structures therefor of structured data, e.g. relational data
- G06F16/23—Updating
- G06F16/2379—Updates performed during online database operations; commit processing
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F7/00—Methods or arrangements for processing data by operating upon the order or content of the data handled
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F16/00—Information retrieval; Database structures therefor; File system structures therefor
- G06F16/20—Information retrieval; Database structures therefor; File system structures therefor of structured data, e.g. relational data
- G06F16/25—Integrating or interfacing systems involving database management systems
- G06F16/252—Integrating or interfacing systems involving database management systems between a Database Management System and a front-end application
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Theoretical Computer Science (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Databases & Information Systems (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Virology (AREA)
- Data Mining & Analysis (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Quality & Reliability (AREA)
- Computer Security & Cryptography (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
a presente invenção apresenta terapias sem interferon para o tratamento de hcv. de preferência, o tratamento ocorre por uma duração de tratamento mais cur-ta, tal como no máximo 12 semanas. em um aspecto, o tratamento compreende ad-ministrar pelo menos dois agentes antivirais de atuação direta a um sujeito com in-fecção por hcv, em que o tratamento dura 12 semanas e não inclui a administração de interferon ou ribavirina, e os ditos pelo menos dois agentes antivirais de atuação direta compreendem (a) composto 1 ou um sal farmaceuticamente aceitável do mesmo e (b) composto 2 ou um sal farmaceuticamente aceitável do mesmo.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562190045P | 2015-07-08 | 2015-07-08 | |
US201562266954P | 2015-12-14 | 2015-12-14 | |
PCT/US2016/041334 WO2017007934A1 (en) | 2015-07-08 | 2016-07-07 | Methods for treating hcv |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112018000383A2 true BR112018000383A2 (pt) | 2018-09-18 |
Family
ID=56497883
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112018000383A BR112018000383A2 (pt) | 2015-07-08 | 2016-07-07 | métodos para tratar hcv |
Country Status (10)
Country | Link |
---|---|
US (2) | US20180177779A1 (pt) |
EP (1) | EP3319604A1 (pt) |
JP (2) | JP6808660B2 (pt) |
CN (1) | CN107921038A (pt) |
AU (1) | AU2016291154B2 (pt) |
BR (1) | BR112018000383A2 (pt) |
CA (1) | CA2991417A1 (pt) |
HK (1) | HK1255481A1 (pt) |
MX (1) | MX2018000240A (pt) |
WO (1) | WO2017007934A1 (pt) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11484534B2 (en) | 2013-03-14 | 2022-11-01 | Abbvie Inc. | Methods for treating HCV |
MX2016012799A (es) | 2014-04-02 | 2016-12-12 | Abbvie Inc | Metodos para tratar el virus de la hepatitis c. |
US20170248953A1 (en) * | 2016-02-25 | 2017-08-31 | Ford Global Technologies, Llc | Autonomous peril control |
JP2018131439A (ja) * | 2017-02-14 | 2018-08-23 | アッヴィ・インコーポレイテッド | Hcvを処置する方法 |
CA2981993A1 (en) * | 2017-08-02 | 2019-02-02 | Abbvie Inc. | Methods for treating hcv |
WO2020106835A1 (en) | 2018-11-20 | 2020-05-28 | Abbvie Inc. | Methods for treating acute hcv |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9394279B2 (en) | 2009-06-11 | 2016-07-19 | Abbvie Inc. | Anti-viral compounds |
NZ608720A (en) | 2010-09-21 | 2015-03-27 | Enanta Pharm Inc | Macrocyclic proline derived hcv serine protease inhibitors |
PT107925A (pt) | 2011-10-21 | 2014-12-03 | Abbvie Inc | Tratamento de combinação de daa (eg. com abt-072 ou abt-333) para utilização no tratamento de hcv |
BR112015006056A2 (pt) * | 2012-09-18 | 2017-07-04 | Abbvie Inc | métodos para tratar hcv |
EP3597190A1 (en) * | 2012-09-18 | 2020-01-22 | AbbVie Inc. | Methods for treating hepatitis c |
RS60881B1 (sr) * | 2013-03-14 | 2020-11-30 | Abbvie Inc | Kombinacija dva antivirusa za lečenje hepatitisa c |
EP3060216A4 (en) * | 2013-10-25 | 2017-06-21 | Abbvie Inc. | Methods for treating hcv |
MX2016012799A (es) * | 2014-04-02 | 2016-12-12 | Abbvie Inc | Metodos para tratar el virus de la hepatitis c. |
-
2016
- 2016-07-07 EP EP16741468.9A patent/EP3319604A1/en not_active Withdrawn
- 2016-07-07 BR BR112018000383A patent/BR112018000383A2/pt not_active Application Discontinuation
- 2016-07-07 JP JP2017568145A patent/JP6808660B2/ja active Active
- 2016-07-07 US US15/738,773 patent/US20180177779A1/en not_active Abandoned
- 2016-07-07 CA CA2991417A patent/CA2991417A1/en not_active Abandoned
- 2016-07-07 WO PCT/US2016/041334 patent/WO2017007934A1/en active Application Filing
- 2016-07-07 CN CN201680051535.9A patent/CN107921038A/zh active Pending
- 2016-07-07 MX MX2018000240A patent/MX2018000240A/es unknown
- 2016-07-07 AU AU2016291154A patent/AU2016291154B2/en active Active
-
2018
- 2018-11-15 HK HK18114657.5A patent/HK1255481A1/zh unknown
-
2020
- 2020-12-08 JP JP2020203169A patent/JP2021050223A/ja active Pending
-
2024
- 2024-03-22 US US18/613,308 patent/US20240232171A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2021050223A (ja) | 2021-04-01 |
JP2018519321A (ja) | 2018-07-19 |
US20240232171A1 (en) | 2024-07-11 |
JP6808660B2 (ja) | 2021-01-06 |
CN107921038A (zh) | 2018-04-17 |
HK1255481A1 (zh) | 2019-08-16 |
MX2018000240A (es) | 2018-03-14 |
US20180177779A1 (en) | 2018-06-28 |
CA2991417A1 (en) | 2017-01-12 |
WO2017007934A1 (en) | 2017-01-12 |
AU2016291154A1 (en) | 2018-01-25 |
AU2016291154B2 (en) | 2021-10-21 |
EP3319604A1 (en) | 2018-05-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
B07G | Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette] |
Free format text: NOTIFICACAO DE DEVOLUCAO DO PEDIDO EM FUNCAO DA REVOGACAO DO ART. 229-C DA LEI NO 9.279, DE 1996, POR FORCA DA LEI NO 14.195, DE 2021 |
|
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |