BR112017017622A2 - reagentes e métodos para a detecção de doenças infecciosas - Google Patents

reagentes e métodos para a detecção de doenças infecciosas

Info

Publication number
BR112017017622A2
BR112017017622A2 BR112017017622A BR112017017622A BR112017017622A2 BR 112017017622 A2 BR112017017622 A2 BR 112017017622A2 BR 112017017622 A BR112017017622 A BR 112017017622A BR 112017017622 A BR112017017622 A BR 112017017622A BR 112017017622 A2 BR112017017622 A2 BR 112017017622A2
Authority
BR
Brazil
Prior art keywords
methods
reagents
infectious diseases
detection
sers
Prior art date
Application number
BR112017017622A
Other languages
English (en)
Inventor
S Tabb Joel
green Omar
Original Assignee
Ionica Sciences
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ionica Sciences filed Critical Ionica Sciences
Publication of BR112017017622A2 publication Critical patent/BR112017017622A2/pt

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G01N21/658—Raman scattering enhancement Raman, e.g. surface plasmons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/16—Aptamers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

são aqui fornecidos reagentes ativos de dispersão de raman intensificada pela superfície (sers) e métodos para detectar um ou mais analitos em uma amostra. ditos reagentes ativos de sers são adaptáveis, sensíveis e fáceis de utilizar no diagnóstico de doenças infecciosas em um paciente, ou a detecção de toxinas, bactérias, vírus, patógenos, hormônios, citocinas, antígenos, anticorpos ou drogas ilícitas em uma amostra biológica. tais métodos podem ser manipulados por policiais, soldados ou profissionais de saúde no campo, e não requerem treinamento especializado.
BR112017017622A 2015-02-19 2016-02-19 reagentes e métodos para a detecção de doenças infecciosas BR112017017622A2 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562118453P 2015-02-19 2015-02-19
US201562263995P 2015-12-07 2015-12-07
US201562264088P 2015-12-07 2015-12-07
PCT/US2016/018600 WO2016134214A1 (en) 2015-02-19 2016-02-19 Reagents and methods for detecting infectious diseases

Publications (1)

Publication Number Publication Date
BR112017017622A2 true BR112017017622A2 (pt) 2018-05-08

Family

ID=56689105

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017017622A BR112017017622A2 (pt) 2015-02-19 2016-02-19 reagentes e métodos para a detecção de doenças infecciosas

Country Status (10)

Country Link
US (2) US11300519B2 (pt)
EP (1) EP3259286A4 (pt)
JP (2) JP6985936B2 (pt)
KR (1) KR20170128342A (pt)
CN (1) CN107849118A (pt)
AU (2) AU2016219897C1 (pt)
BR (1) BR112017017622A2 (pt)
CA (1) CA2976963A1 (pt)
IL (1) IL254024B (pt)
WO (1) WO2016134214A1 (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2702033T3 (es) 2011-11-21 2019-02-27 Abay Sa Amplificación de la señal en inmunoensayos
TWI691716B (zh) 2014-08-13 2020-04-21 美商艾巴希斯公司 電漿特異性結合搭配物檢定中之信號放大
JP6944438B2 (ja) 2015-08-04 2021-10-06 ゾエティス サービシズ リミテッド ライアビリティ カンパニー 溶液ベースのプラズモン特異的結合パートナーアッセイにおけるシグナル増幅
US20170328912A1 (en) * 2016-05-10 2017-11-16 Regents Of The University Of Minnesota Glycopolymer capture matrix for use with surface-enhanced raman spectroscopy detection and related systems and methods
IL295118A (en) 2017-01-30 2022-09-01 Zoetis Services Llc Solution-based specific plasmon binding assays and metallic nanostructures
CN110546484A (zh) * 2017-02-03 2019-12-06 社会福祉法人三星生命公益财团 用于诊断急性发热性疾病的现场即时系统和方法
WO2018143684A1 (ko) * 2017-02-03 2018-08-09 사회복지법인 삼성생명공익재단 급성 열성 질환을 진단하기 위한 현장 진단 시스템 및 방법
CN108310397B (zh) * 2018-04-26 2021-02-26 郑州轻工业学院 一种具有sers/荧光双模态靶向肿瘤细胞成像的诊疗试剂及其制备方法
CN108760715B (zh) * 2018-05-07 2021-11-09 同济大学 检测多氯联苯表面增强拉曼散射核酸适配体传感器及应用
TWI686599B (zh) * 2018-05-24 2020-03-01 國立清華大學 塵蟎抗原檢測系統及方法
CN109001178B (zh) * 2018-06-26 2020-09-25 中国科学院合肥物质科学研究院 表面增强拉曼散射检测器件及其制备方法
JP2022107068A (ja) * 2019-04-26 2022-07-21 バイオ・アクセラレーター株式会社 観察システム、観察方法
CN110079522B (zh) * 2019-05-14 2022-12-13 南方科技大学 一种单层二硫化钼的使用方法和dna的切割方法
CN110937582B (zh) * 2019-12-10 2021-10-19 山东师范大学 一种硒化锌纳米线及其作为表面增强拉曼散射基底的应用
CN111504976B (zh) * 2020-04-29 2021-12-28 深圳米瑞科信息技术有限公司 石墨烯/Cu-Cu2S复合材料及其制备方法
FR3109818A1 (fr) * 2020-04-30 2021-11-05 Greentropism Méthode de détection de la présence d’un agent pathogène dans un liquide biologique
CN111665356A (zh) * 2020-05-29 2020-09-15 深圳网联光仪科技有限公司 一种基于sers的病毒检测方法及装置
CN111624186B (zh) * 2020-06-24 2021-03-16 江南大学 一种基于荧光和拉曼双信号增强的肠毒素光谱分析方法
GB202017378D0 (en) * 2020-11-02 2020-12-16 Univ Birmingham Single point variant detection
CN112526120B (zh) * 2020-11-19 2024-05-14 山东省农业科学院农业质量标准与检测技术研究所 一种基于spr技术检测沙丁胺醇的方法
WO2022169421A1 (en) * 2021-02-04 2022-08-11 Silver Factory Technology Pte Ltd Surface-enhanced raman scattering (sers) platform for analysis
CN113075194A (zh) * 2021-03-23 2021-07-06 武汉康义盛生物科技有限公司 一种新型的拉曼光谱检测试剂盒及其使用方法
CN114113034A (zh) * 2021-11-17 2022-03-01 肇庆市华师大光电产业研究院 一种多壁碳纳米管“手指”的制备方法及其在表面增强拉曼散射检测中的应用
CN115531539B (zh) * 2022-09-19 2023-09-15 海南大学 一种近红外sers信号增强纳米探针及其制备方法和在一体化诊疗感染细菌中的应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050227252A1 (en) * 2002-08-20 2005-10-13 Moon John A Diffraction grating-based encoded articles for multiplexed experiments
JP2009523406A (ja) * 2005-11-15 2009-06-25 オクソニカ・インコーポレーテッド 生体剤（ｂｉｏａｇｅｎｔｓ）の検出のためのＳＥＲＳに基づく方法
BRPI0809138B8 (pt) * 2007-03-20 2021-07-27 Becton Dickinson Co método para detectar a presença ou quantidade de um ou mais analitos em uma amostra biológica
CA2709456A1 (en) * 2007-12-31 2009-07-16 The Regents Of The University Of California Sers-based, single step, real-time detection of protein kinase and/or phosphatase activity
US20100105053A1 (en) * 2008-10-10 2010-04-29 Hansang Cho Aptamer based sensors and related methods and systems
KR101247610B1 (ko) * 2009-12-11 2013-03-26 서울대학교산학협력단 라만 활성분자가 나노입자 이합체의 접합부에 위치한 이합체 코어쉘 나노 입자, 이의 용도 및 이의 제조방법
US9689801B2 (en) 2009-12-22 2017-06-27 Agency For Science, Technology And Research SERS-based analyte detection
US20120302940A1 (en) * 2011-05-26 2012-11-29 Jackson State University Popcorn Shape Gold Nanoparticle For Targeted Diagnosis, Photothermal Treatment and In-Situ Monitoring Therapy Response for Cancer and Multiple Drug Resistance Bacteria
CN104380105B (zh) * 2011-11-02 2017-04-12 开普敦大学 生物样品中的分析物的检测和/或定量方法
CN102608102A (zh) * 2012-03-24 2012-07-25 南京师范大学 一种基于表面增强拉曼光谱的人乳腺癌细胞mcf-7的特异性检测方法
US12016682B2 (en) * 2013-03-14 2024-06-25 The Regents Of The University Of California In-vivo monitoring of molecular targets
CN104237203B (zh) * 2014-09-28 2016-08-24 苏州大学 一种定量检测水样汞离子浓度的sers传感器及其制备方法

Also Published As

Publication number Publication date
US20180217068A1 (en) 2018-08-02
JP2022033117A (ja) 2022-02-28
WO2016134214A1 (en) 2016-08-25
EP3259286A4 (en) 2018-07-11
US20220146431A1 (en) 2022-05-12
US11300519B2 (en) 2022-04-12
EP3259286A1 (en) 2017-12-27
JP6985936B2 (ja) 2021-12-22
CA2976963A1 (en) 2016-08-25
IL254024A0 (en) 2017-10-31
JP2018512598A (ja) 2018-05-17
IL254024B (en) 2021-07-29
AU2016219897A1 (en) 2017-09-21
AU2016219897B2 (en) 2022-01-27
AU2016219897C1 (en) 2022-04-21
CN107849118A (zh) 2018-03-27
KR20170128342A (ko) 2017-11-22
AU2022202775A1 (en) 2022-05-19

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B350 Update of information on the portal [chapter 15.35 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

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B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2762 DE 12-12-2023 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.