BR112017007039A2 - reator para hidrólise enzimática de um material. - Google Patents

reator para hidrólise enzimática de um material.

Info

Publication number
BR112017007039A2
BR112017007039A2 BR112017007039-1A BR112017007039A BR112017007039A2 BR 112017007039 A2 BR112017007039 A2 BR 112017007039A2 BR 112017007039 A BR112017007039 A BR 112017007039A BR 112017007039 A2 BR112017007039 A2 BR 112017007039A2
Authority
BR
Brazil
Prior art keywords
reactor
enzymatic hydrolysis
chamber
heat
temperature
Prior art date
Application number
BR112017007039-1A
Other languages
English (en)
Other versions
BR112017007039B1 (pt
BR112017007039B8 (pt
Inventor
Aglen Lars
Original Assignee
N & U As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from NO20141197A external-priority patent/NO20141197A1/no
Application filed by N & U As filed Critical N & U As
Publication of BR112017007039A2 publication Critical patent/BR112017007039A2/pt
Publication of BR112017007039B1 publication Critical patent/BR112017007039B1/pt
Publication of BR112017007039B8 publication Critical patent/BR112017007039B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/14—Production of inert gas mixtures; Use of inert gases in general
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/02—Apparatus for enzymology or microbiology with agitation means; with heat exchange means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/04—Apparatus for enzymology or microbiology with gas introduction means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/16—Apparatus for enzymology or microbiology containing, or adapted to contain, solid media
    • C12M1/18—Multiple fields or compartments
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/40—Apparatus specially designed for the use of free, immobilised, or carrier-bound enzymes, e.g. apparatus containing a fluidised bed of immobilised enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/18—Apparatus specially designed for the use of free, immobilized or carrier-bound enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/06—Tubular
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/24—Gas permeable parts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/44—Multiple separable units; Modules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/58—Reaction vessels connected in series or in parallel
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/06—Nozzles; Sprayers; Spargers; Diffusers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/06—Nozzles; Sprayers; Spargers; Diffusers
    • C12M29/08—Air lift
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/24—Recirculation of gas
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/18—Heat exchange systems, e.g. heat jackets or outer envelopes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/18—Heat exchange systems, e.g. heat jackets or outer envelopes
    • C12M41/22—Heat exchange systems, e.g. heat jackets or outer envelopes in contact with the bioreactor walls
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M45/00—Means for pre-treatment of biological substances
    • C12M45/09—Means for pre-treatment of biological substances by enzymatic treatment

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Clinical Laboratory Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Thermal Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)

Abstract

é provido um reator para hidrólise enzimática de uma matéria-prima compreendendo na sequência: i) - um primeiro trocador de calor (hex1) adaptado para aquecer a matéria-prima provida ao reator a uma temperatura em uma faixa que favorece a hidrólise enzimática, ii) - um reator compreendendo várias câmaras do reator (r1-r6) ligadas em série, separadas por válvulas vedáveis (v1-v6), iii) - um segundo trocador de calor (hex2) adaptado para aquecer a mistura reacional a uma temperatura mais elevada do que a temperatura variando em favorecer a hidrólise enzimática, o reator sendo formado com as câmaras tubulares do reator inclinadas (r1-r6) montadas para formar um reator com eixo geométrico vertical, a primeira câmara do reator (r1) sendo a câmara verticalmente mais elevada do reator, ao mesmo tempo que pelo menos uma câmara do reator é adaptada para ser agitada com um gás inerte de fluxo contínuo.
BR112017007039A 2014-10-07 2015-10-05 Reator para hidrólise enzimática de um material. BR112017007039B8 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
NO20141197A NO20141197A1 (no) 2014-10-07 2014-10-07 Reaktor for enzymatisk hydrolyse av et råmateriale
NO20141197 2014-10-07
NO20150943 2015-07-15
NO20150943A NO342290B1 (no) 2014-10-07 2015-07-15 Reaktor for enzymatisk hydrolyse av et råmateriale
PCT/NO2015/050183 WO2016056922A1 (en) 2014-10-07 2015-10-05 Compact reactor for enzymatic treatment

Publications (3)

Publication Number Publication Date
BR112017007039A2 true BR112017007039A2 (pt) 2018-01-30
BR112017007039B1 BR112017007039B1 (pt) 2022-02-22
BR112017007039B8 BR112017007039B8 (pt) 2022-09-13

Family

ID=55653423

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017007039A BR112017007039B8 (pt) 2014-10-07 2015-10-05 Reator para hidrólise enzimática de um material.

Country Status (14)

Country Link
US (1) US11072770B2 (pt)
EP (1) EP3204486B1 (pt)
JP (1) JP6671614B2 (pt)
CN (1) CN107109326B (pt)
AU (1) AU2015328779B2 (pt)
BR (1) BR112017007039B8 (pt)
CA (1) CA2962402C (pt)
CL (1) CL2017000832A1 (pt)
CY (1) CY1122847T1 (pt)
DK (1) DK179596B1 (pt)
PL (1) PL3204486T3 (pt)
RS (1) RS60218B1 (pt)
SI (1) SI3204486T1 (pt)
WO (1) WO2016056922A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10201900158PA (en) * 2019-01-08 2020-08-28 Jie Xiong Jonathan Yeo Manufacturing facility

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5141861A (en) 1983-11-03 1992-08-25 Bio Process Innovation, Inc. Method of use of a multi-stage reactor-separator with simultaneous product separation
JPH07106154B2 (ja) 1986-05-28 1995-11-15 花王株式会社 酵素もしくは微生物反応方法
CN88212729U (zh) * 1988-01-20 1988-11-09 周栋梁 连续发酵反应器
US5409639A (en) * 1993-06-25 1995-04-25 Verona Inc. Hardwood floor cleaner composition
IT1262502B (it) 1993-08-27 1996-06-28 Consiglio Nazionale Ricerche Impianto a fotobioreattori tubolari per la coltura industriale di microrganismi fotosintetici.
US5733758A (en) 1997-01-10 1998-03-31 Nguyen; Quang A. Tower reactors for bioconversion of lignocellulosic material
US6451268B1 (en) * 1999-04-16 2002-09-17 Minerals Technologies Inc. Method and apparatus for continuous gas liquid reactions
DK175501B1 (da) 2002-12-02 2004-11-15 Green Earth Anlæg og fremgangsmåde til kontinuerlig hydrolyse af et proteinholdigt animalsk eller vegetabilsk råmateriale
WO2006024242A1 (en) * 2004-08-31 2006-03-09 Biotech Progress, A.S. Method and devices for the continuous processing of renewable raw materials
NO322996B1 (no) * 2005-05-27 2006-12-18 Lars Aglen Sylindrisk reaktor for kontinuerlig behandling av en materialblanding under omrøring og med definert oppholdstid.
FR2943685B1 (fr) * 2009-03-25 2011-04-29 Microphyt Reacteur photosynthetique pour la culture de microorganiques et procede de culture de microorganismes
CN201495212U (zh) * 2009-09-17 2010-06-02 王利杰 高效乙酸生物反应器
CN102791887A (zh) 2010-01-18 2012-11-21 株式会社Ihi 生物质处理装置
US20130323714A1 (en) 2012-06-04 2013-12-05 Alan T. Cheng System and method for micro-aeration based fermentation
MX2015005047A (es) 2012-10-22 2015-12-01 Abengoa Bioenergy New Technologies Llc Metodos y aparatos relacionados con la licuefaccion de suspensiones de biomasa.

Also Published As

Publication number Publication date
EP3204486B1 (en) 2020-03-25
PL3204486T3 (pl) 2020-07-13
CL2017000832A1 (es) 2017-11-10
DK201770211A1 (en) 2017-04-03
AU2015328779B2 (en) 2019-11-14
RS60218B1 (sr) 2020-06-30
CN107109326A (zh) 2017-08-29
CN107109326B (zh) 2020-04-28
JP6671614B2 (ja) 2020-03-25
EP3204486A4 (en) 2018-07-04
WO2016056922A1 (en) 2016-04-14
BR112017007039B1 (pt) 2022-02-22
US20170306280A1 (en) 2017-10-26
SI3204486T1 (sl) 2020-07-31
AU2015328779A1 (en) 2017-04-27
DK179596B1 (en) 2019-02-25
US11072770B2 (en) 2021-07-27
CA2962402A1 (en) 2016-04-14
JP2017537651A (ja) 2017-12-21
BR112017007039B8 (pt) 2022-09-13
CY1122847T1 (el) 2021-05-05
EP3204486A1 (en) 2017-08-16
CA2962402C (en) 2023-03-21

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B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
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