BR112017001958A2 - composições de núcleo - Google Patents
composições de núcleoInfo
- Publication number
- BR112017001958A2 BR112017001958A2 BR112017001958A BR112017001958A BR112017001958A2 BR 112017001958 A2 BR112017001958 A2 BR 112017001958A2 BR 112017001958 A BR112017001958 A BR 112017001958A BR 112017001958 A BR112017001958 A BR 112017001958A BR 112017001958 A2 BR112017001958 A2 BR 112017001958A2
- Authority
- BR
- Brazil
- Prior art keywords
- core compositions
- mixture
- active pharmaceutical
- pharmaceutical ingredient
- adsorbing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Molecular Biology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
a presente invenção refere-se a um processo para adsorção de um ingrediente farmacêutico ativo em um substrato, compreendendo as etapas de (a) adicionar e misturar um adsorvente inerte a uma forma não sólida compreendendo o ingrediente farmacêutico ativo, formando assim uma mistura; e (b) secar a mistura para formar um material sólido quebradiço.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462032029P | 2014-08-01 | 2014-08-01 | |
PCT/US2015/043127 WO2016019252A1 (en) | 2014-08-01 | 2015-07-31 | Core compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112017001958A2 true BR112017001958A2 (pt) | 2017-11-21 |
Family
ID=53879786
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112017001958A BR112017001958A2 (pt) | 2014-08-01 | 2015-07-31 | composições de núcleo |
Country Status (7)
Country | Link |
---|---|
US (1) | US20160030345A1 (pt) |
EP (1) | EP3174527B1 (pt) |
CN (1) | CN106794142A (pt) |
BR (1) | BR112017001958A2 (pt) |
CA (1) | CA2956947C (pt) |
RU (1) | RU2017106094A (pt) |
WO (1) | WO2016019252A1 (pt) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10245284B2 (en) * | 2015-08-19 | 2019-04-02 | Alpex Pharma S.A. | Granular composition for oral administration |
DE102016218604A1 (de) | 2016-09-27 | 2018-03-29 | Constantin Adams | Partikuläres Stoffgemisch, vorzugsweise zur Verwendung bei der Prophylaxe und/oder Behandlung einer Atemwegsstörung |
EP3823598A2 (en) * | 2018-07-18 | 2021-05-26 | Glatt Gmbh | Immediate release formulations of cannabinoids |
CN112107694B (zh) * | 2020-10-30 | 2022-07-22 | 黄山中皇制药有限公司 | 一种喜炎平干混悬剂 |
CN114452262A (zh) * | 2022-03-03 | 2022-05-10 | 成都恒瑞制药有限公司 | 一种盐酸西替利嗪片及其制备方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100226979A1 (en) * | 2006-03-21 | 2010-09-09 | Jubilant Organosys Limited | Taste Masked Phamaceutical Composition for Oral Solid Dosage form and Process for Preparing the Same Using Magnesium Aluminium Silicate |
US20110097414A1 (en) * | 2007-02-26 | 2011-04-28 | Sandal Roshan Lal | Pharmaceutical compositions comprising adsorbate of fenofibrate |
CN101380474B (zh) * | 2007-09-06 | 2012-07-25 | 北京大学 | 用于口服制剂的pH敏感性固体药物组合物及制备方法 |
EP2072042A1 (en) * | 2007-12-21 | 2009-06-24 | Lek Pharmaceuticals D.D. | Active pharmaceutical ingredient on solid support, amorphous and with improved solubility |
US9629809B2 (en) * | 2008-07-21 | 2017-04-25 | Si Group, Inc. | High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms |
JP2010106007A (ja) * | 2008-08-14 | 2010-05-13 | Sony Corp | 薬剤徐放剤、吸着剤、機能性食品、マスク及び吸着シート |
KR20110110097A (ko) * | 2008-10-28 | 2011-10-06 | 에이전시 포 사이언스, 테크놀로지 앤드 리서치 | 수난용성 성분을 위한 메조포러스 물질 부형제 |
CN102697761B (zh) * | 2012-06-01 | 2013-09-04 | 北京大学 | 一种布洛芬缓释固体组合物及其制备方法 |
-
2015
- 2015-07-31 WO PCT/US2015/043127 patent/WO2016019252A1/en active Application Filing
- 2015-07-31 BR BR112017001958A patent/BR112017001958A2/pt not_active Application Discontinuation
- 2015-07-31 CN CN201580053828.6A patent/CN106794142A/zh not_active Withdrawn
- 2015-07-31 EP EP15751191.6A patent/EP3174527B1/en active Active
- 2015-07-31 RU RU2017106094A patent/RU2017106094A/ru unknown
- 2015-07-31 US US14/814,795 patent/US20160030345A1/en not_active Abandoned
- 2015-07-31 CA CA2956947A patent/CA2956947C/en active Active
Also Published As
Publication number | Publication date |
---|---|
CA2956947C (en) | 2022-11-08 |
WO2016019252A1 (en) | 2016-02-04 |
EP3174527A1 (en) | 2017-06-07 |
CA2956947A1 (en) | 2016-02-04 |
RU2017106094A (ru) | 2018-09-04 |
US20160030345A1 (en) | 2016-02-04 |
CN106794142A (zh) | 2017-05-31 |
EP3174527B1 (en) | 2021-02-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |