BR112017000338A2 - ?composição de hidrogel, cobertura para feridas, gel, creme ou loção, e, processo para preparação de uma composição de hidrogel? - Google Patents
?composição de hidrogel, cobertura para feridas, gel, creme ou loção, e, processo para preparação de uma composição de hidrogel?Info
- Publication number
- BR112017000338A2 BR112017000338A2 BR112017000338A BR112017000338A BR112017000338A2 BR 112017000338 A2 BR112017000338 A2 BR 112017000338A2 BR 112017000338 A BR112017000338 A BR 112017000338A BR 112017000338 A BR112017000338 A BR 112017000338A BR 112017000338 A2 BR112017000338 A2 BR 112017000338A2
- Authority
- BR
- Brazil
- Prior art keywords
- hydrogel composition
- lotion
- cream
- gel
- preparing
- Prior art date
Links
- 239000000017 hydrogel Substances 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title abstract 5
- 239000006071 cream Substances 0.000 title 1
- 239000000499 gel Substances 0.000 title 1
- 239000006210 lotion Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000004433 Thermoplastic polyurethane Substances 0.000 abstract 1
- 229920006037 cross link polymer Polymers 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000000178 monomer Substances 0.000 abstract 1
- 229920002803 thermoplastic polyurethane Polymers 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0052—Mixtures of macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
- A61K31/125—Camphor; Nuclear substituted derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/042—Gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/87—Polyurethanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/225—Mixtures of macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/60—Liquid-swellable gel-forming materials, e.g. super-absorbents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
- A61L26/0066—Medicaments; Biocides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
- A61L26/008—Hydrogels or hydrocolloids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L33/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- C08L33/02—Homopolymers or copolymers of acids; Metal or ammonium salts thereof
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L33/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- C08L33/04—Homopolymers or copolymers of esters
- C08L33/06—Homopolymers or copolymers of esters of esters containing only carbon, hydrogen and oxygen, which oxygen atoms are present only as part of the carboxyl radical
- C08L33/08—Homopolymers or copolymers of acrylic acid esters
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L75/00—Compositions of polyureas or polyurethanes; Compositions of derivatives of such polymers
- C08L75/04—Polyurethanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/48—Thickener, Thickening system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Dispersion Chemistry (AREA)
- Hematology (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Birds (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pain & Pain Management (AREA)
- Cosmetics (AREA)
- Polyurethanes Or Polyureas (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Abstract
uma composição de hidrogel a partir de um polímero reticulado derivado de um ou mais monómeros carboxílicos polimerizáveis olefinicamente insaturados e uma composição de poliuretano termoplástico são descritas. o hidrogel exibe elevada tensão de rendimento em baixo cisalhamento. a composição de hidrogel provê materiais úteis para cuidados pessoais, cuidados de saúde, aplicações médicas e farmacêuticas, entre outros.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462022245P | 2014-07-09 | 2014-07-09 | |
US62/022245 | 2014-07-09 | ||
PCT/US2015/039649 WO2016007692A1 (en) | 2014-07-09 | 2015-07-09 | Hydrogel compositions |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112017000338A2 true BR112017000338A2 (pt) | 2017-11-07 |
BR112017000338B1 BR112017000338B1 (pt) | 2021-02-23 |
Family
ID=53682871
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112017000338-4A BR112017000338B1 (pt) | 2014-07-09 | 2015-07-09 | Composição de combinação de hidrogel, cobertura para feridas, gel,creme ou loção, e, processo para preparação de uma composição de combinaçãode hidrogel |
Country Status (10)
Country | Link |
---|---|
US (1) | US10493178B2 (pt) |
EP (1) | EP3166650B1 (pt) |
JP (1) | JP6873897B2 (pt) |
KR (1) | KR102455927B1 (pt) |
CN (1) | CN106687149B (pt) |
BR (1) | BR112017000338B1 (pt) |
ES (1) | ES2860763T3 (pt) |
MX (1) | MX2017000368A (pt) |
TW (1) | TWI707909B (pt) |
WO (1) | WO2016007692A1 (pt) |
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GB0808376D0 (en) | 2008-05-08 | 2008-06-18 | Bristol Myers Squibb Co | Wound dressing |
GB0817796D0 (en) | 2008-09-29 | 2008-11-05 | Convatec Inc | wound dressing |
GB201020236D0 (en) | 2010-11-30 | 2011-01-12 | Convatec Technologies Inc | A composition for detecting biofilms on viable tissues |
WO2012078784A1 (en) | 2010-12-08 | 2012-06-14 | Convatec Technologies Inc. | Wound exudate system accessory |
JP5965409B2 (ja) | 2010-12-08 | 2016-08-03 | コンバテック・テクノロジーズ・インコーポレイテッドConvatec Technologies Inc | 創傷滲出液を評価するための統合システム |
GB201115182D0 (en) | 2011-09-02 | 2011-10-19 | Trio Healthcare Ltd | Skin contact material |
GB2497406A (en) | 2011-11-29 | 2013-06-12 | Webtec Converting Llc | Dressing with a perforated binder layer |
CN105008611A (zh) | 2012-12-20 | 2015-10-28 | 康沃特克科技公司 | 化学改性的纤维素纤维的处理 |
TW201800069A (zh) | 2016-03-30 | 2018-01-01 | 康華特科技有限公司 | 傷口中微生物感染檢測方法 |
CA3019445A1 (en) | 2016-03-30 | 2017-12-14 | Synovo Gmbh | Detecting microbial infection in wounds |
MX2019000239A (es) | 2016-07-08 | 2019-09-06 | Convatec Technologies Inc | Sistema de presion negativa flexible. |
WO2018009879A1 (en) | 2016-07-08 | 2018-01-11 | Convatec Technologies Inc. | Fluid flow sensing |
CA3030151A1 (en) | 2016-07-08 | 2018-01-11 | Convatec Technologies Inc. | Fluid collection apparatus |
KR101921727B1 (ko) * | 2016-12-28 | 2018-11-23 | 주식회사 제네웰 | 실리콘 수지 조성물, 이의 제조방법 및 이를 포함하는 흉터 치료제 |
EP3691688B1 (en) * | 2017-10-06 | 2021-12-08 | Laboratorio Reig Jofré, S.A. | Hydrogel compositions for the treatment of molluscum contagiosum |
CN107652662B (zh) * | 2017-11-06 | 2020-09-08 | 东莞市雄林新材料科技股份有限公司 | 一种具有高耐热性的生物基tpu材料及其制备方法 |
KR102120962B1 (ko) * | 2017-12-27 | 2020-06-10 | 주식회사 티앤엘 | 개선된 점착성을 가진 하이드로겔 드레싱 |
US12076215B2 (en) | 2019-06-03 | 2024-09-03 | Convatec Limited | Methods and devices to disrupt and contain pathogens |
CN110294831B (zh) * | 2019-07-04 | 2021-08-13 | 南京大学 | 一种用于智能窗户的弹性热致变色材料制备方法及其产物和应用 |
CN110694095A (zh) * | 2019-10-23 | 2020-01-17 | 北京幸福益生再生医学科技有限公司 | 一种再生硅矿物质材料皮肤修复敷贴及其制备方法 |
US11771819B2 (en) | 2019-12-27 | 2023-10-03 | Convatec Limited | Low profile filter devices suitable for use in negative pressure wound therapy systems |
US11331221B2 (en) | 2019-12-27 | 2022-05-17 | Convatec Limited | Negative pressure wound dressing |
CN113913361A (zh) * | 2021-10-13 | 2022-01-11 | 安徽省立医院(中国科学技术大学附属第一医院) | 一种用于研究细胞机械力感应的生物试剂盒及其制备方法 |
KR20240093626A (ko) * | 2021-10-21 | 2024-06-24 | 에보니크 수퍼압소버 게엠베하 | 향상된 탄성 거동을 갖는 고속 초흡수제의 제조 |
CN114381083B (zh) * | 2021-12-17 | 2023-03-24 | 浙江理工大学上虞工业技术研究院有限公司 | 一种角膜接触镜用抗菌抗氧化水凝胶及其制备方法 |
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WO2012068059A1 (en) * | 2010-11-18 | 2012-05-24 | Lubrizol Advanced Materials, Inc. | Polymer for surgeons gloves |
JP2015517874A (ja) * | 2012-05-29 | 2015-06-25 | スリーエム イノベイティブ プロパティズ カンパニー | 超吸収体及び中間体を備えるポリマー発泡体を含む吸収性物品 |
CN203425113U (zh) * | 2013-05-31 | 2014-02-12 | 天津法莫西医药科技有限公司 | 卡波姆水凝胶浸渍海绵保护层的医用敷料 |
CN103520767B (zh) * | 2013-10-28 | 2016-08-17 | 山东赛克赛斯药业科技有限公司 | 一种抗菌促愈水凝胶敷料及其制备方法 |
CN103623454B (zh) * | 2013-11-28 | 2015-04-22 | 北京健康广济贸易有限公司 | 一种高通透率薄膜敷料 |
JP2015166418A (ja) * | 2014-03-03 | 2015-09-24 | 住友精化株式会社 | 増粘組成物 |
CN107027292A (zh) * | 2014-05-05 | 2017-08-08 | 路博润先进材料公司 | 均匀膜组合物 |
-
2015
- 2015-07-09 EP EP15739463.6A patent/EP3166650B1/en active Active
- 2015-07-09 JP JP2017501023A patent/JP6873897B2/ja active Active
- 2015-07-09 ES ES15739463T patent/ES2860763T3/es active Active
- 2015-07-09 WO PCT/US2015/039649 patent/WO2016007692A1/en active Application Filing
- 2015-07-09 US US15/324,888 patent/US10493178B2/en active Active
- 2015-07-09 CN CN201580048250.5A patent/CN106687149B/zh active Active
- 2015-07-09 MX MX2017000368A patent/MX2017000368A/es active IP Right Grant
- 2015-07-09 BR BR112017000338-4A patent/BR112017000338B1/pt not_active IP Right Cessation
- 2015-07-09 TW TW104122301A patent/TWI707909B/zh not_active IP Right Cessation
- 2015-07-09 KR KR1020177003581A patent/KR102455927B1/ko active IP Right Grant
Also Published As
Publication number | Publication date |
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US20170202999A1 (en) | 2017-07-20 |
EP3166650A1 (en) | 2017-05-17 |
KR20170028431A (ko) | 2017-03-13 |
CN106687149A (zh) | 2017-05-17 |
TWI707909B (zh) | 2020-10-21 |
KR102455927B1 (ko) | 2022-10-17 |
EP3166650B1 (en) | 2021-03-03 |
CN106687149B (zh) | 2021-02-19 |
ES2860763T3 (es) | 2021-10-05 |
US10493178B2 (en) | 2019-12-03 |
JP6873897B2 (ja) | 2021-05-19 |
WO2016007692A1 (en) | 2016-01-14 |
BR112017000338B1 (pt) | 2021-02-23 |
TW201609925A (zh) | 2016-03-16 |
JP2017521528A (ja) | 2017-08-03 |
MX2017000368A (es) | 2017-05-12 |
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