BR112016020738A2 - Composição de liberação controlada e método - Google Patents
Composição de liberação controlada e métodoInfo
- Publication number
- BR112016020738A2 BR112016020738A2 BR112016020738A BR112016020738A BR112016020738A2 BR 112016020738 A2 BR112016020738 A2 BR 112016020738A2 BR 112016020738 A BR112016020738 A BR 112016020738A BR 112016020738 A BR112016020738 A BR 112016020738A BR 112016020738 A2 BR112016020738 A2 BR 112016020738A2
- Authority
- BR
- Brazil
- Prior art keywords
- controlled release
- release composition
- dosage form
- coating
- coalescing agent
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5015—Organic compounds, e.g. fats, sugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/282—Organic compounds, e.g. fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/282—Organic compounds, e.g. fats
- A61K9/2826—Sugars or sugar alcohols, e.g. sucrose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2893—Tablet coating processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5089—Processes
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
COMPOSIÇÃO DE LIBERAÇÃO CONTROLADA E MÉTODO. Em um aspecto, a presente invenção é direcionada a um método de fazer uma forma de dosagem sólida de liberação controlada tendo uma camada de revestimento de etilcelulose, cuja camada compreende um agente de coalescência que é um éster orgânico tendo um Valor HLB de 3 a 8. O uso de tal agente de coalescência permite a formação de um revestimento de liberação controlada eficaz sem a necessidade de ainda uma etapa de cura após o processo de revestimento. Em outros aspectos, a invenção diz respeito a uma dispersão aquosa útil em tal método, bem como a forma de dosagem revestida produzida.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461951065P | 2014-03-11 | 2014-03-11 | |
US61/951,065 | 2014-03-11 | ||
US201462073365P | 2014-10-31 | 2014-10-31 | |
US62/073,365 | 2014-10-31 | ||
PCT/US2015/018743 WO2015138200A1 (en) | 2014-03-11 | 2015-03-04 | Controlled release composition and method |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112016020738A2 true BR112016020738A2 (pt) | 2017-08-15 |
BR112016020738B1 BR112016020738B1 (pt) | 2023-04-11 |
Family
ID=54067754
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112016020738-6A BR112016020738B1 (pt) | 2014-03-11 | 2015-03-04 | Composição de liberação controlada e método |
Country Status (8)
Country | Link |
---|---|
US (3) | US20150258033A1 (pt) |
EP (1) | EP3116483B1 (pt) |
JP (1) | JP6616780B2 (pt) |
CN (1) | CN106102723B (pt) |
BR (1) | BR112016020738B1 (pt) |
CA (1) | CA2940684C (pt) |
MX (1) | MX2016011729A (pt) |
WO (1) | WO2015138200A1 (pt) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
USRE48948E1 (en) | 2008-04-18 | 2022-03-01 | Warsaw Orthopedic, Inc. | Clonidine compounds in a biodegradable polymer |
KR102113261B1 (ko) | 2018-03-28 | 2020-05-20 | 주식회사 엘지화학 | 용출 제어형 비료 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4330338A (en) * | 1978-10-02 | 1982-05-18 | Purdue Research Foundation | Pharmaceutical coating composition, and preparation and dosages so coated |
US4629753A (en) | 1981-11-18 | 1986-12-16 | The Lubrizol Corporation | Water dispersed rust inhibitive coating compositions |
NZ221411A (en) * | 1986-08-11 | 1989-10-27 | Innovata Biomed Ltd | Pharmaceutical compositions containing microcapsules and a surfactant |
AU601528B2 (en) * | 1986-12-22 | 1990-09-13 | Ortho-Mcneil Pharmaceutical, Inc. | Resilient transdermal drug-delivery device and compositions and devices employing fatty acid esters/ethers of alkanediols and percutaneous absorption enhancers |
US5273760A (en) | 1991-12-24 | 1993-12-28 | Euroceltigue, S.A. | Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer |
US5853740A (en) * | 1996-08-07 | 1998-12-29 | Abbott Laboratories | Delivery system for pharmaceutical agents encapsulated with oils |
US5695551A (en) * | 1996-12-09 | 1997-12-09 | Dow Corning Corporation | Water repellent composition |
US20030180352A1 (en) * | 1999-11-23 | 2003-09-25 | Patel Mahesh V. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
EP1896002A4 (en) * | 2005-06-27 | 2009-11-25 | Biovail Lab Int Srl | BUPROPIONAL SALT FORMULATIONS WITH MODIFIED RELEASE |
AU2006284053B2 (en) * | 2005-08-22 | 2010-04-22 | Novartis Ag | Pharmaceutical compositions comprising a pH-dependent drug, a pH modifier and a retarding agent |
US7829148B2 (en) | 2006-02-07 | 2010-11-09 | Fmc Corporation | Coating process to produce controlled release coatings |
US8088414B2 (en) * | 2006-02-07 | 2012-01-03 | Fmc Corporation | Latex or pseudolatex compositions, coatings and coating processes |
WO2010060008A1 (en) | 2008-11-21 | 2010-05-27 | Elementis Specialties, Inc. | Voc-free coalescing agent |
CN101919803A (zh) * | 2010-07-16 | 2010-12-22 | 钟术光 | 一种控释制剂 |
-
2015
- 2015-03-04 BR BR112016020738-6A patent/BR112016020738B1/pt active IP Right Grant
- 2015-03-04 MX MX2016011729A patent/MX2016011729A/es unknown
- 2015-03-04 CA CA2940684A patent/CA2940684C/en active Active
- 2015-03-04 CN CN201580013110.4A patent/CN106102723B/zh active Active
- 2015-03-04 EP EP15761728.3A patent/EP3116483B1/en active Active
- 2015-03-04 JP JP2016556754A patent/JP6616780B2/ja active Active
- 2015-03-04 WO PCT/US2015/018743 patent/WO2015138200A1/en active Application Filing
- 2015-03-04 US US14/638,490 patent/US20150258033A1/en not_active Abandoned
-
2018
- 2018-08-03 US US16/054,019 patent/US20180360763A1/en not_active Abandoned
-
2022
- 2022-06-09 US US17/836,314 patent/US20230072225A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
CA2940684C (en) | 2023-05-02 |
WO2015138200A1 (en) | 2015-09-17 |
CN106102723B (zh) | 2021-06-25 |
JP6616780B2 (ja) | 2019-12-04 |
CN106102723A (zh) | 2016-11-09 |
CA2940684A1 (en) | 2015-09-17 |
MX2016011729A (es) | 2016-10-28 |
BR112016020738B1 (pt) | 2023-04-11 |
EP3116483A4 (en) | 2017-11-08 |
EP3116483B1 (en) | 2021-04-21 |
US20230072225A1 (en) | 2023-03-09 |
US20180360763A1 (en) | 2018-12-20 |
EP3116483A1 (en) | 2017-01-18 |
US20150258033A1 (en) | 2015-09-17 |
JP2017507164A (ja) | 2017-03-16 |
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Legal Events
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B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
B25A | Requested transfer of rights approved |
Owner name: DUPONT NUTRITION USA, INC. (US) |
|
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 04/03/2015, OBSERVADAS AS CONDICOES LEGAIS |