BR112015032554A8 - moduladores do receptor de bradicinina e seu uso - Google Patents
moduladores do receptor de bradicinina e seu usoInfo
- Publication number
- BR112015032554A8 BR112015032554A8 BR112015032554A BR112015032554A BR112015032554A8 BR 112015032554 A8 BR112015032554 A8 BR 112015032554A8 BR 112015032554 A BR112015032554 A BR 112015032554A BR 112015032554 A BR112015032554 A BR 112015032554A BR 112015032554 A8 BR112015032554 A8 BR 112015032554A8
- Authority
- BR
- Brazil
- Prior art keywords
- receptor modulators
- bradykinin receptor
- bradykinin
- âbradykinin
- useâ
- Prior art date
Links
- 102000010183 Bradykinin receptor Human genes 0.000 title abstract 2
- 108050001736 Bradykinin receptor Proteins 0.000 title abstract 2
- 201000006474 Brain Ischemia Diseases 0.000 abstract 1
- 206010008120 Cerebral ischaemia Diseases 0.000 abstract 1
- 208000004454 Hyperalgesia Diseases 0.000 abstract 1
- 208000035154 Hyperesthesia Diseases 0.000 abstract 1
- 208000002193 Pain Diseases 0.000 abstract 1
- 206010008118 cerebral infarction Diseases 0.000 abstract 1
- 230000002526 effect on cardiovascular system Effects 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000005962 receptors Human genes 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/18—Kallidins; Bradykinins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
resumo da patente de invenã§ã£o para: âmoduladores do receptor de bradicinina e seu usoâ. esta invenã§ã£o refere-se geralmente a novos peptãdeos biolã³gicos e purificadas, como os moduladores de receptores da bradicinina, para uso no tratamento e/ou prevenã§ã£o de doenã§as inflamatã³rias, dor, hiperalgesia, doenã§as isquãªmicas cardiovasculares e/ou cerebrais, em indivãduos que dele necessitam.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH11682013 | 2013-06-25 | ||
PCT/IB2014/001162 WO2014207534A2 (en) | 2013-06-25 | 2014-06-24 | Bradykinin receptor modulators and use thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112015032554A2 BR112015032554A2 (pt) | 2017-08-22 |
BR112015032554A8 true BR112015032554A8 (pt) | 2018-01-23 |
Family
ID=52142768
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112015032554A BR112015032554A8 (pt) | 2013-06-25 | 2014-06-24 | moduladores do receptor de bradicinina e seu uso |
Country Status (5)
Country | Link |
---|---|
US (1) | US9920096B2 (pt) |
EP (1) | EP3013851A4 (pt) |
JP (1) | JP2016528192A (pt) |
BR (1) | BR112015032554A8 (pt) |
WO (1) | WO2014207534A2 (pt) |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4560655A (en) | 1982-12-16 | 1985-12-24 | Immunex Corporation | Serum-free cell culture medium and process for making same |
US4657866A (en) | 1982-12-21 | 1987-04-14 | Sudhir Kumar | Serum-free, synthetic, completely chemically defined tissue culture media |
US4767704A (en) | 1983-10-07 | 1988-08-30 | Columbia University In The City Of New York | Protein-free culture medium |
US4693993A (en) | 1985-06-13 | 1987-09-15 | Stewart John M | Bradykinin antagonist peptides |
GB8516415D0 (en) | 1985-06-28 | 1985-07-31 | Celltech Ltd | Culture of animal cells |
US4927762A (en) | 1986-04-01 | 1990-05-22 | Cell Enterprises, Inc. | Cell culture medium with antioxidant |
ATE135397T1 (de) | 1988-09-23 | 1996-03-15 | Cetus Oncology Corp | Zellenzuchtmedium für erhöhtes zellenwachstum, zur erhöhung der langlebigkeit und expression der produkte |
US5122469A (en) | 1990-10-03 | 1992-06-16 | Genentech, Inc. | Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins |
CA2137367A1 (en) * | 1992-06-05 | 1993-12-23 | Amrit K. Judd | Peptides having platelet-derived growth factor (pdgf) activity |
JPH07330795A (ja) * | 1994-06-07 | 1995-12-19 | Toagosei Co Ltd | ペプチドおよびモノクローナル抗体 |
WO1998007746A1 (en) * | 1996-08-19 | 1998-02-26 | Universite De Sherbrooke | B1-bradykinin receptor antagonists and use thereof |
US20020165174A1 (en) * | 1997-01-31 | 2002-11-07 | Gill Parkash S. | Methods and compositions for antisense VEGF oligonucleotides |
JP2001002586A (ja) * | 1999-06-21 | 2001-01-09 | Toagosei Co Ltd | 重粒子線療法用薬剤 |
US7045133B2 (en) * | 2000-01-18 | 2006-05-16 | Ludwig Institute For Cancer Research | VEGF-D/VEGF-C/VEGF peptidomimetic inhibitor |
DE10141749A1 (de) | 2000-08-29 | 2002-03-14 | Max Delbrueck Centrum | Mittel zur Beeinflussung der Angiogenese |
US7863239B2 (en) * | 2005-01-24 | 2011-01-04 | Pepscan Systems B.V. | Binding compounds, immunogenic compounds and peptidomimetics |
WO2010111625A1 (en) * | 2009-03-27 | 2010-09-30 | Zymogenetics, Inc. | Compositions and methods for using multispecific-binding proteins comprising an antibody-receptor combination |
US20100305002A1 (en) * | 2009-04-27 | 2010-12-02 | Roswell Park Cancer Institute | Reagents and Methods for Producing Bioactive Secreted Peptides |
EP2568995B1 (en) * | 2010-05-14 | 2016-07-20 | Max-Delbrück-Centrum für Molekulare Medizin | Therapeutic use of agonists of bradykinin receptor 1 or 2, for modulation collateral blood vessel growth |
WO2012088563A1 (en) | 2010-11-24 | 2012-07-05 | Vegenics Pty Limited | Vegfr-2-specific forms of vegf-d and vegf-c and uses thereof |
-
2014
- 2014-06-24 BR BR112015032554A patent/BR112015032554A8/pt not_active Application Discontinuation
- 2014-06-24 EP EP14818114.2A patent/EP3013851A4/en not_active Withdrawn
- 2014-06-24 WO PCT/IB2014/001162 patent/WO2014207534A2/en active Application Filing
- 2014-06-24 US US14/392,278 patent/US9920096B2/en active Active
- 2014-06-24 JP JP2016522885A patent/JP2016528192A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP3013851A4 (en) | 2016-12-28 |
JP2016528192A (ja) | 2016-09-15 |
BR112015032554A2 (pt) | 2017-08-22 |
WO2014207534A3 (en) | 2015-04-09 |
US20160176929A1 (en) | 2016-06-23 |
US9920096B2 (en) | 2018-03-20 |
EP3013851A2 (en) | 2016-05-04 |
WO2014207534A2 (en) | 2014-12-31 |
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B08G | Application fees: restoration [chapter 8.7 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
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Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |