BR112015031416A2 - métodos para a promoção do desenvolvimento e/ou da saúde neuronal compreendendo a administração de uma combinação de ácido docosa-hexaenoico e ácido alfa-lipoico - Google Patents
métodos para a promoção do desenvolvimento e/ou da saúde neuronal compreendendo a administração de uma combinação de ácido docosa-hexaenoico e ácido alfa-lipoicoInfo
- Publication number
- BR112015031416A2 BR112015031416A2 BR112015031416A BR112015031416A BR112015031416A2 BR 112015031416 A2 BR112015031416 A2 BR 112015031416A2 BR 112015031416 A BR112015031416 A BR 112015031416A BR 112015031416 A BR112015031416 A BR 112015031416A BR 112015031416 A2 BR112015031416 A2 BR 112015031416A2
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- acid
- health
- alpha lipoic
- administering
- Prior art date
Links
- MBMBGCFOFBJSGT-KUBAVDMBSA-N all-cis-docosa-4,7,10,13,16,19-hexaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O MBMBGCFOFBJSGT-KUBAVDMBSA-N 0.000 title abstract 4
- AGBQKNBQESQNJD-UHFFFAOYSA-N lipoic acid Chemical compound OC(=O)CCCCC1CCSS1 AGBQKNBQESQNJD-UHFFFAOYSA-N 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 229940090949 docosahexaenoic acid Drugs 0.000 title abstract 2
- 235000020669 docosahexaenoic acid Nutrition 0.000 title abstract 2
- 235000019136 lipoic acid Nutrition 0.000 title abstract 2
- 230000007472 neurodevelopment Effects 0.000 title abstract 2
- 230000001737 promoting effect Effects 0.000 title abstract 2
- 229960002663 thioctic acid Drugs 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 4
- 235000016709 nutrition Nutrition 0.000 abstract 3
- 102000010445 Lactoferrin Human genes 0.000 abstract 1
- 108010063045 Lactoferrin Proteins 0.000 abstract 1
- 230000018109 developmental process Effects 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- CSSYQJWUGATIHM-IKGCZBKSSA-N l-phenylalanyl-l-lysyl-l-cysteinyl-l-arginyl-l-arginyl-l-tryptophyl-l-glutaminyl-l-tryptophyl-l-arginyl-l-methionyl-l-lysyl-l-lysyl-l-leucylglycyl-l-alanyl-l-prolyl-l-seryl-l-isoleucyl-l-threonyl-l-cysteinyl-l-valyl-l-arginyl-l-arginyl-l-alanyl-l-phenylal Chemical compound C([C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)C1=CC=CC=C1 CSSYQJWUGATIHM-IKGCZBKSSA-N 0.000 abstract 1
- 229940078795 lactoferrin Drugs 0.000 abstract 1
- 235000021242 lactoferrin Nutrition 0.000 abstract 1
- 230000001537 neural effect Effects 0.000 abstract 1
- 235000013406 prebiotics Nutrition 0.000 abstract 1
- 239000006041 probiotic Substances 0.000 abstract 1
- 230000000529 probiotic effect Effects 0.000 abstract 1
- 235000018291 probiotics Nutrition 0.000 abstract 1
- 230000008625 synaptic signaling Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/20—Dietetic milk products not covered by groups A23C9/12 - A23C9/18
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
- A23L33/12—Fatty acids or derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/19—Dairy proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7012—Compounds having a free or esterified carboxyl group attached, directly or through a carbon chain, to a carbon atom of the saccharide radical, e.g. glucuronic acid, neuraminic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/01—Hydrolysed proteins; Derivatives thereof
- A61K38/011—Hydrolysed proteins; Derivatives thereof from plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/01—Hydrolysed proteins; Derivatives thereof
- A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
- A61K38/018—Hydrolysed proteins; Derivatives thereof from animals from milk
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/40—Transferrins, e.g. lactoferrins, ovotransferrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Botany (AREA)
- Pediatric Medicine (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
a presente descrição refere-se a métodos para a promoção da saúde e/ou do desenvolvimento neuronal em um indivíduo, por meio do fornecimento de composições nutricionais compreendendo ácido docosa-hexaenoico e o ácido alfa-lipoico. a composição nutricional pode incluir ainda lactoferrina, um prebiótico, um probiótico, e misturas dos mesmos. adicionalmente, a presente descrição fornece métodos para acelerar o desenvolvimento da atividade neuronal e/ou o reforço da sinalização por sinapse eletroquímica, fornecendo a(s) composição(ões) nutricional(is), aqui revelada(s), a um indivíduo alvo.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13/942,827 US9226914B2 (en) | 2013-07-16 | 2013-07-16 | Methods for promoting neuronal development and/or health |
PCT/US2014/043532 WO2015009407A1 (en) | 2013-07-16 | 2014-06-21 | Methods for promoting neuronal development and/or health comprising administration of a combination of docosahexaenoic acid and alpha-lipoic acid |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112015031416A2 true BR112015031416A2 (pt) | 2017-07-25 |
Family
ID=51210794
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112015031416A BR112015031416A2 (pt) | 2013-07-16 | 2014-06-21 | métodos para a promoção do desenvolvimento e/ou da saúde neuronal compreendendo a administração de uma combinação de ácido docosa-hexaenoico e ácido alfa-lipoico |
Country Status (13)
Country | Link |
---|---|
US (1) | US9226914B2 (pt) |
EP (1) | EP3102196A1 (pt) |
CN (1) | CN105358144B (pt) |
AR (1) | AR096942A1 (pt) |
AU (1) | AU2014290767A1 (pt) |
BR (1) | BR112015031416A2 (pt) |
CA (1) | CA2918460A1 (pt) |
HK (1) | HK1221658A1 (pt) |
MX (1) | MX2016000423A (pt) |
PH (1) | PH12016500025A1 (pt) |
SG (1) | SG11201510330YA (pt) |
TW (1) | TW201542101A (pt) |
WO (1) | WO2015009407A1 (pt) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20150290261A1 (en) * | 2014-04-10 | 2015-10-15 | Mead Johnson Nutrition Company | Methods of use for probiotics and prebiotics |
US10525016B2 (en) * | 2015-06-03 | 2020-01-07 | Mead Johnson Nutrition Company | Nutritional compositions containing an elevated level of inositol and uses thereof |
US10617701B2 (en) * | 2015-07-10 | 2020-04-14 | Mead Johnson Nutrition Company | Nutritional compositions containing phosphatidylethanolamine, sphingomyelin and docosahexaenoic acid |
CN110891982B (zh) | 2017-04-17 | 2023-12-22 | 芝加哥大学 | 向肠道递送短链脂肪酸以用于人体保健和疾病治疗的聚合物材料 |
US11197917B2 (en) | 2017-12-01 | 2021-12-14 | ByHeart, Inc. | Formulations for nutritional support in subjects in need thereof |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE61701B1 (en) | 1986-07-17 | 1994-11-30 | Morinaga Milk Industry Co Ltd | Process for producing bovine lactoferrin in high purity |
US5407957A (en) | 1990-02-13 | 1995-04-18 | Martek Corporation | Production of docosahexaenoic acid by dinoflagellates |
DK165090D0 (da) | 1990-07-09 | 1990-07-09 | Kem En Tec As | Konglomererede partikler |
WO1992012711A1 (en) | 1991-01-24 | 1992-08-06 | Martek Corporation | Microbial oil mixtures and uses thereof |
US5374567A (en) | 1993-05-20 | 1994-12-20 | The United States Of America As Represented By The Secretary Of The Navy | Operational amplifier using bipolar junction transistors in silicon-on-sapphire |
EP0744901B1 (en) | 1994-02-16 | 2001-12-05 | Pharming Intellectual Property BV | Isolation of lactoferrin from milk |
SE9503926D0 (sv) | 1995-11-07 | 1995-11-07 | Pharmacia Biotech Ab | Adsorptionsförfarande och separationsmedium |
GB9715444D0 (en) | 1997-07-22 | 1997-09-24 | Scotia Holdings Plc | Therapeutic and dietary compositions |
EP1087828B1 (en) | 1998-06-18 | 2008-09-17 | Upfront Chromatography A/S | Expanded bed adsorption system |
AU5823801A (en) | 2000-05-12 | 2001-11-20 | Upfront Chromatography As | A bed adsorption system |
US6332533B1 (en) | 2000-08-29 | 2001-12-25 | H.H.H. Incorprorated | Media holder mouse pad |
EP2272378B1 (en) | 2001-06-01 | 2014-08-06 | Upfront Chromatography A/S | Fractionation of protein containing mixtures |
AU2003218623B2 (en) | 2002-03-07 | 2008-01-17 | Upfront Chromatography A/S | A process of isolating lactoferrin |
US20050107338A1 (en) | 2003-11-17 | 2005-05-19 | Seidman Michael D. | Nutritional supplement enhancing mitochondrial function |
CN103734746B (zh) * | 2004-07-19 | 2017-01-11 | 纽崔西亚公司 | 天冬氨酸用于调节血中葡萄糖水平的用途 |
US8883814B2 (en) | 2006-06-05 | 2014-11-11 | Keyview Labs, Inc. | Compositions and methods for enhancing brain function |
US20080003330A1 (en) | 2006-06-30 | 2008-01-03 | Ricardo Rueda | Infant formulas for early brain development |
EP2251030A1 (en) | 2009-05-12 | 2010-11-17 | Nestec S.A. | Lactoferrin and brain health and development in infants |
EP2258218A1 (en) | 2009-06-02 | 2010-12-08 | Nestec S.A. | Nutritional Composition for Supporting Brain Development and Function of Toddlers |
US20120219526A1 (en) | 2009-10-29 | 2012-08-30 | Nestec S.A. | Nutritional compositions comprising lactoferrin and probiotics and kits of parts thereof |
WO2011069987A1 (en) * | 2009-12-08 | 2011-06-16 | Nestec S.A. | Infant formula with probiotics and milk fat globule membrane components |
EP2554058A4 (en) * | 2010-03-31 | 2013-12-25 | Vegenat S A | FUNCTIONAL FOOD SUPPLEMENT, IN PARTICULAR FOR NUTRITIONAL AND PREVENTION AND IMPROVEMENT OF NEUROLOGICAL ILLNESSES, NEURODEEGENERATIVE ILLNESSES OR COGNITIVE DISORDERS |
US8968722B2 (en) * | 2010-12-29 | 2015-03-03 | Mead Johnson Nutrition Company | Milk-based nutritional compositions containing lactoferrin and uses thereof |
CN102318827B (zh) | 2011-07-15 | 2013-02-27 | 浙江康恩贝健康产品有限公司 | 一种促进神经系统发育的营养素组合物及保健品 |
EP2609814A1 (en) | 2011-12-30 | 2013-07-03 | Nestec S.A. | Lactobacillus reuteri DSM 17938 for the development of cognitive function |
US20140179775A1 (en) | 2012-02-29 | 2014-06-26 | Mead Johnson Nutrition Company | Neurogenesis screening method and uses thereof |
US20140199265A1 (en) | 2013-01-11 | 2014-07-17 | Mead Johnson Nutrition Company | Nutritional compositions containing a neurologic component and uses thereof |
-
2013
- 2013-07-16 US US13/942,827 patent/US9226914B2/en not_active Expired - Fee Related
-
2014
- 2014-06-21 EP EP14740058.4A patent/EP3102196A1/en not_active Withdrawn
- 2014-06-21 BR BR112015031416A patent/BR112015031416A2/pt not_active Application Discontinuation
- 2014-06-21 MX MX2016000423A patent/MX2016000423A/es unknown
- 2014-06-21 WO PCT/US2014/043532 patent/WO2015009407A1/en active Application Filing
- 2014-06-21 CN CN201480040471.3A patent/CN105358144B/zh not_active Expired - Fee Related
- 2014-06-21 SG SG11201510330YA patent/SG11201510330YA/en unknown
- 2014-06-21 CA CA2918460A patent/CA2918460A1/en not_active Abandoned
- 2014-06-21 AU AU2014290767A patent/AU2014290767A1/en not_active Abandoned
- 2014-06-26 TW TW103122081A patent/TW201542101A/zh unknown
- 2014-07-16 AR ARP140102630A patent/AR096942A1/es unknown
-
2016
- 2016-01-05 PH PH12016500025A patent/PH12016500025A1/en unknown
- 2016-08-18 HK HK16109891.3A patent/HK1221658A1/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US9226914B2 (en) | 2016-01-05 |
CA2918460A1 (en) | 2015-01-22 |
AU2014290767A1 (en) | 2015-12-24 |
EP3102196A1 (en) | 2016-12-14 |
PH12016500025A1 (en) | 2016-03-28 |
AR096942A1 (es) | 2016-02-10 |
WO2015009407A1 (en) | 2015-01-22 |
SG11201510330YA (en) | 2016-01-28 |
CN105358144B (zh) | 2018-05-11 |
CN105358144A (zh) | 2016-02-24 |
US20150023923A1 (en) | 2015-01-22 |
MX2016000423A (es) | 2016-04-20 |
HK1221658A1 (zh) | 2017-06-09 |
TW201542101A (zh) | 2015-11-16 |
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