BR112015026827A2 - Formas polimórficas de cloridrato de nilotinibe - Google Patents

Formas polimórficas de cloridrato de nilotinibe

Info

Publication number
BR112015026827A2
BR112015026827A2 BR112015026827A BR112015026827A BR112015026827A2 BR 112015026827 A2 BR112015026827 A2 BR 112015026827A2 BR 112015026827 A BR112015026827 A BR 112015026827A BR 112015026827 A BR112015026827 A BR 112015026827A BR 112015026827 A2 BR112015026827 A2 BR 112015026827A2
Authority
BR
Brazil
Prior art keywords
nilotinib hydrochloride
polymorphic forms
nilotinib
hydrochloride
forms
Prior art date
Application number
BR112015026827A
Other languages
English (en)
Inventor
Peddy Vishweshwar
Chennuru Ramanaiah
Ramakrishnan Srividya
Original Assignee
Dr Reddy´S Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Reddy´S Laboratories Ltd filed Critical Dr Reddy´S Laboratories Ltd
Publication of BR112015026827A2 publication Critical patent/BR112015026827A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

FORMAS POLIMÓRFICAS DE CLORIDRATO DE NILOTINIBE. Formas Cristalinas R5, R5a, R5b e R6 do cloridrato de nilotinibe e processos para a sua preparação.
BR112015026827A 2013-04-24 2014-04-23 Formas polimórficas de cloridrato de nilotinibe BR112015026827A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1795CH2013 2013-04-24
PCT/IB2014/060935 WO2014174456A2 (en) 2013-04-24 2014-04-23 Polymorphic forms of nilotinib hydrochloride

Publications (1)

Publication Number Publication Date
BR112015026827A2 true BR112015026827A2 (pt) 2017-09-05

Family

ID=51792459

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015026827A BR112015026827A2 (pt) 2013-04-24 2014-04-23 Formas polimórficas de cloridrato de nilotinibe

Country Status (11)

Country Link
US (2) US9580408B2 (pt)
EP (2) EP3461818A1 (pt)
JP (2) JP2016522182A (pt)
CN (1) CN105324375A (pt)
AU (1) AU2014259029B2 (pt)
BR (1) BR112015026827A2 (pt)
CA (1) CA2912902A1 (pt)
EA (1) EA201592032A1 (pt)
MX (1) MX2015014897A (pt)
NZ (1) NZ714378A (pt)
WO (1) WO2014174456A2 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2013332205B2 (en) 2012-10-15 2017-08-31 Apotex Inc. Solid forms of Nilotinib hydrochloride
WO2014174456A2 (en) 2013-04-24 2014-10-30 Dr. Reddys Laboratories Limited Polymorphic forms of nilotinib hydrochloride
WO2016020891A1 (en) * 2014-08-08 2016-02-11 Dr. Reddy’S Laboratories Limited Process for the preparation of polymorphic forms of nilotinib
CN106478603B (zh) * 2015-08-25 2021-01-01 江苏豪森药业集团有限公司 尼洛替尼盐酸盐的新晶型及其制备方法和医药用途
EP3404025B1 (en) * 2017-05-16 2019-12-04 F.I.S.- Fabbrica Italiana Sintetici S.p.A. Process for the preparation of pure nilotinib and its salt
CZ2017821A3 (cs) 2017-12-20 2019-07-03 Zentiva, K.S. Léková forma obsahující krystalický nilotinib
JP7409696B2 (ja) * 2018-06-15 2024-01-09 ハンダ ファーマシューティカルズ インコーポレイテッド キナーゼ阻害剤の塩およびその組成物
US20210380557A1 (en) * 2018-11-05 2021-12-09 Laurus Labs Limited Crystalline form of nilotinib hydrochloride, process for its preparation and pharmaceutical composition containing the same

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GT200600316A (es) 2005-07-20 2007-04-02 Sales de 4-metilo-n-(3-(4-metilo-imidazol-1-ilo)-5-trifluorometilo-fenilo)-3-(4-piridina-3-ilo-pirimidina-2-iloamino)- benzamida.
GT200600315A (es) 2005-07-20 2007-03-19 Formas cristalinas de 4-metilo-n-[3-(4-metilo-imidazol-1-ilo)-5-trifluorometilo-fenilo]-3-(4-pyridina-3-ilo-pirimidina-2-iloamino)-benzamida
WO2010009402A2 (en) * 2008-07-17 2010-01-21 Teva Pharmaceutical Industries Ltd. Nilotinib intermediates and preparation thereof
ES2394258T3 (es) * 2008-11-05 2013-01-30 Teva Pharmaceutical Industries Ltd. Formas cristalinas de Nilotinib HCL
WO2011033307A1 (en) * 2009-09-17 2011-03-24 Generics [Uk] Limited Nilotinib dihydrochloride salt
IN2010KO00035A (pt) * 2010-01-15 2016-09-02
PL2571863T3 (pl) * 2010-06-21 2016-03-31 Teva Pharma Sole nilotynibu i ich postacie krystaliczne
CN102453024B (zh) 2010-10-27 2014-09-03 浙江九洲药业股份有限公司 一种尼罗替尼盐酸盐晶型及其制备方法
IN2010CH03577A (pt) 2010-11-26 2012-07-20 Hetero Research Foundation
US9061028B2 (en) * 2012-02-15 2015-06-23 Natco Pharma Limited Process for the preparation of Nilotinib
WO2014174456A2 (en) 2013-04-24 2014-10-30 Dr. Reddys Laboratories Limited Polymorphic forms of nilotinib hydrochloride

Also Published As

Publication number Publication date
CN105324375A (zh) 2016-02-10
JP2016522182A (ja) 2016-07-28
EA201592032A1 (ru) 2016-04-29
AU2014259029A1 (en) 2015-12-10
US9580408B2 (en) 2017-02-28
CA2912902A1 (en) 2014-10-30
EP2989090A2 (en) 2016-03-02
JP2019014762A (ja) 2019-01-31
WO2014174456A2 (en) 2014-10-30
WO2014174456A3 (en) 2015-02-19
US20160130252A1 (en) 2016-05-12
US9981947B2 (en) 2018-05-29
EP2989090A4 (en) 2017-01-18
MX2015014897A (es) 2016-03-07
EP3461818A1 (en) 2019-04-03
US20170260162A1 (en) 2017-09-14
AU2014259029B2 (en) 2018-08-16
NZ714378A (en) 2020-08-28

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B15K Others concerning applications: alteration of classification

Free format text: A CLASSIFICACAO ANTERIOR ERA: C07D 401/14

Ipc: C07D 401/14 (2006.01), A61P 35/02 (2006.01)

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements