BR112015022468A2 - síntese do gás óxido nítrico para inalação - Google Patents

síntese do gás óxido nítrico para inalação

Info

Publication number
BR112015022468A2
BR112015022468A2 BR112015022468A BR112015022468A BR112015022468A2 BR 112015022468 A2 BR112015022468 A2 BR 112015022468A2 BR 112015022468 A BR112015022468 A BR 112015022468A BR 112015022468 A BR112015022468 A BR 112015022468A BR 112015022468 A2 BR112015022468 A2 BR 112015022468A2
Authority
BR
Brazil
Prior art keywords
chamber
nitric oxide
control parameters
patient
synthesis
Prior art date
Application number
BR112015022468A
Other languages
English (en)
Other versions
BR112015022468B1 (pt
Inventor
Yu Binglan
Hickcox Matthew
Hardin Paul
M Zapol Warren
Original Assignee
Massachusetts Gen Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Gen Hospital filed Critical Massachusetts Gen Hospital
Publication of BR112015022468A2 publication Critical patent/BR112015022468A2/pt
Publication of BR112015022468B1 publication Critical patent/BR112015022468B1/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/12—Preparation of respiratory gases or vapours by mixing different gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/02—Inhalators with activated or ionised fluids, e.g. electrohydrodynamic [EHD] or electrostatic devices; Ozone-inhalators with radioactive tagged particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0057—Pumps therefor
    • A61M16/0063—Compressors
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    • A61M16/0072—Tidal volume piston pumps
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    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
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    • B01D53/34—Chemical or biological purification of waste gases
    • B01D53/46—Removing components of defined structure
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    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B21/00—Nitrogen; Compounds thereof
    • C01B21/20—Nitrogen oxides; Oxyacids of nitrogen; Salts thereof
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    • A61M16/201—Controlled valves
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    • A61M2016/0018—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Plasma & Fusion (AREA)
  • Inorganic Chemistry (AREA)
  • Environmental & Geological Engineering (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Oxygen, Ozone, And Oxides In General (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

abstract: in some additional aspects, an apparatus can include a chamber having an inlet valve for receiving a reactant gas and an outlet valve for delivering a product gas, a piston positioned inside the chamber and configured to move along a length of the chamber for adjusting pressure in the chamber, a sensor for collecting information related to one or more conditions of a respiratory system associated with a patient, a controller for determining one or more control parameters based on the collected information, and one or more pairs of electrodes positioned inside the chamber for initiating a series of electric arcs external to the patient to generate nitric oxide based on the determined control parameters. tradução do resumo resumo patente de invenção: síntese do gás óxido nítrico para i-nalação a patente de invenção refere-se a um aparelho que pode incluir uma câmara que possui uma válvula de entrada para receber um gás reagente e uma válvula de saída para o fornecimento de um produto gasoso, um êmbolo posicionado no interior da câmara e confi-gurado para se mover ao longo de um comprimento da câmara de a-juste de pressão na câmara, um sensor para a colhetar informação relacionada com um ou mais condições de um sistema respiratório as-sociado a um paciente, um controlador para a determinar um ou mais parâmetros de controle com base na informação recolhida, e um ou mais pares de eletrodos posicionados no interior da câmara para inici-ar uma série de arcos elétricos externos ao paciente para gerar o óxido nítrico com base nos parâmetros de controle determinados.
BR112015022468-7A 2013-03-15 2014-03-14 Aparelho e método para síntese do gás óxido nítrico para inalação BR112015022468B1 (pt)

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PCT/US2014/027986 WO2014143842A1 (en) 2013-03-15 2014-03-14 Synthesis of nitric oxide gas for inhalation

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RU2692953C2 (ru) 2019-06-28
BR112015022468B1 (pt) 2022-11-01
MX2019014954A (es) 2020-02-19
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CN105431191A (zh) 2016-03-23
PL2968827T3 (pl) 2019-08-30
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AU2014228152A1 (en) 2015-10-01
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CA2906660C (en) 2021-05-25
RU2015143714A (ru) 2017-04-20
US20200345966A1 (en) 2020-11-05
US20160030699A1 (en) 2016-02-04
MX2019014953A (es) 2020-02-19
US10279139B2 (en) 2019-05-07
AU2021201157A1 (en) 2021-03-11
HK1222587A1 (zh) 2017-07-07
JP2016516488A (ja) 2016-06-09
CA2906660A1 (en) 2014-09-18
MX370384B (es) 2019-12-11
US20180221619A1 (en) 2018-08-09
EP2968827B1 (en) 2019-02-20
JP2021007861A (ja) 2021-01-28
KR102447456B1 (ko) 2022-09-23
AU2018206762A1 (en) 2018-08-16
CN105431191B (zh) 2018-08-24
AU2018206762B2 (en) 2020-11-26
AU2021201157B2 (en) 2023-04-27
JP6787946B2 (ja) 2020-11-18
US10773047B2 (en) 2020-09-15

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