BR112015013248A2 - método de determinação do fluxo sanguíneo através das artérias coronárias, processador (36) para determinar o fluxo sanguíneo através das artérias coronárias, dispositivo de imageamento e programa de computador - Google Patents
método de determinação do fluxo sanguíneo através das artérias coronárias, processador (36) para determinar o fluxo sanguíneo através das artérias coronárias, dispositivo de imageamento e programa de computadorInfo
- Publication number
- BR112015013248A2 BR112015013248A2 BR112015013248A BR112015013248A BR112015013248A2 BR 112015013248 A2 BR112015013248 A2 BR 112015013248A2 BR 112015013248 A BR112015013248 A BR 112015013248A BR 112015013248 A BR112015013248 A BR 112015013248A BR 112015013248 A2 BR112015013248 A2 BR 112015013248A2
- Authority
- BR
- Brazil
- Prior art keywords
- coronary arteries
- blood flow
- myocardial muscle
- determining blood
- determining
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
- A61B6/50—Clinical applications
- A61B6/504—Clinical applications involving diagnosis of blood vessels, e.g. by angiography
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
- A61B6/02—Devices for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
- A61B6/03—Computerised tomographs
- A61B6/032—Transmission computed tomography [CT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
- A61B6/48—Diagnostic techniques
- A61B6/481—Diagnostic techniques involving the use of contrast agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
- A61B6/48—Diagnostic techniques
- A61B6/482—Diagnostic techniques involving multiple energy imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
- A61B6/50—Clinical applications
- A61B6/503—Clinical applications involving diagnosis of heart
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
- A61B6/52—Devices using data or image processing specially adapted for radiation diagnosis
- A61B6/5205—Devices using data or image processing specially adapted for radiation diagnosis involving processing of raw data to produce diagnostic data
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
- A61B6/52—Devices using data or image processing specially adapted for radiation diagnosis
- A61B6/5211—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data
- A61B6/5217—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data extracting a diagnostic or physiological parameter from medical diagnostic data
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/0002—Inspection of images, e.g. flaw detection
- G06T7/0012—Biomedical image inspection
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
- A61B2090/3966—Radiopaque markers visible in an X-ray image
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
- A61B6/52—Devices using data or image processing specially adapted for radiation diagnosis
- A61B6/5288—Devices using data or image processing specially adapted for radiation diagnosis involving retrospective matching to a physiological signal
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/10—Image acquisition modality
- G06T2207/10072—Tomographic images
- G06T2207/10081—Computed x-ray tomography [CT]
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/30—Subject of image; Context of image processing
- G06T2207/30004—Biomedical image processing
- G06T2207/30048—Heart; Cardiac
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/30—Subject of image; Context of image processing
- G06T2207/30004—Biomedical image processing
- G06T2207/30101—Blood vessel; Artery; Vein; Vascular
- G06T2207/30104—Vascular flow; Blood flow; Perfusion
Abstract
resumo método de determinação do fluxo sanguíneo através das artérias coronárias, processador (36) para determinar o fluxo sanguíneo através das artérias coronárias, dispositivo de imageamento e programa de computador a presente invenção refere-se a um método de determinação do fluxo sanguíneo através das artérias coronárias que compreende gerar (s1) um conjunto de dados da imagem 3d pelo menos das artérias coronárias e do músculo miocardial, gerar (s2) um conjunto de dados de marcador 3d pelo menos do músculo miocardial a partir de um conjunto de dados 3d de dupla energia ou espectral obtido após a administração de um marcador, sendo que o dito conjunto de dados de marcador 3d indica a quantia do dito marcador contida dentro de voxels do dito músculo miocardial, subdividir (s3) o músculo miocardial em segmentos de músculo miocardial, determinar (s4) qual artéria coronária supre os segmentos respectivos de músculo miocardial, determinar (s5) o volume de sangue que flui para os segmentos respectivos de músculo miocardial a partir do dito conjunto de dados de marcador 3d e determinar (s6) o volume total de sangue que flui para uma artéria coronária de interesse, através da soma do volume de sangue que flui para todos os segmentos de músculo miocardial supridos pela dita artéria coronária. 1/1
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261735624P | 2012-12-11 | 2012-12-11 | |
PCT/IB2013/060294 WO2014091339A1 (en) | 2012-12-11 | 2013-11-21 | Method of determining the blood flow through coronary arteries |
Publications (1)
Publication Number | Publication Date |
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BR112015013248A2 true BR112015013248A2 (pt) | 2017-07-11 |
Family
ID=50029163
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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BR112015013248A BR112015013248A2 (pt) | 2012-12-11 | 2013-11-21 | método de determinação do fluxo sanguíneo através das artérias coronárias, processador (36) para determinar o fluxo sanguíneo através das artérias coronárias, dispositivo de imageamento e programa de computador |
Country Status (7)
Country | Link |
---|---|
US (1) | US9867584B2 (pt) |
EP (1) | EP2932469B1 (pt) |
JP (1) | JP5953438B2 (pt) |
CN (1) | CN104871211B (pt) |
BR (1) | BR112015013248A2 (pt) |
RU (1) | RU2015128005A (pt) |
WO (1) | WO2014091339A1 (pt) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8200466B2 (en) | 2008-07-21 | 2012-06-12 | The Board Of Trustees Of The Leland Stanford Junior University | Method for tuning patient-specific cardiovascular simulations |
US9405886B2 (en) | 2009-03-17 | 2016-08-02 | The Board Of Trustees Of The Leland Stanford Junior University | Method for determining cardiovascular information |
US8315812B2 (en) | 2010-08-12 | 2012-11-20 | Heartflow, Inc. | Method and system for patient-specific modeling of blood flow |
US10111633B2 (en) * | 2013-12-04 | 2018-10-30 | Koninklijke Philips N.V. | Local FFR estimation and visualisation for improved functional stenosis analysis |
WO2015092588A2 (en) * | 2013-12-17 | 2015-06-25 | Koninklijke Philips N.V. | Spectral image data processing |
US20150164450A1 (en) * | 2013-12-18 | 2015-06-18 | Siemens Medical Solutions Usa, Inc. | System and Method for Real Time 4D Quantification |
US9747525B2 (en) * | 2014-06-16 | 2017-08-29 | Siemens Healthcare Gmbh | Method and system for improved hemodynamic computation in coronary arteries |
EP3160335B1 (en) * | 2014-06-30 | 2023-09-20 | Koninklijke Philips N.V. | Apparatus for determining a fractional flow reserve value |
JP6635695B2 (ja) * | 2014-07-16 | 2020-01-29 | キヤノンメディカルシステムズ株式会社 | 画像処理装置、医用画像診断装置、及び画像処理方法 |
US10658085B2 (en) | 2014-08-29 | 2020-05-19 | Knu-Industry Coorporation Foundation | Method for determining patient-specific blood vessel information |
US9386933B2 (en) | 2014-08-29 | 2016-07-12 | Heartflow, Inc. | Systems and methods for determination of blood flow characteristics and pathologies through modeling of myocardial blood supply |
WO2016172206A1 (en) * | 2015-04-20 | 2016-10-27 | The Johns Hopkins University | Patient-specific virtual intervention laboratory to prevent stroke |
EP3313275B1 (en) | 2015-06-25 | 2021-08-04 | Analytics For Life Inc. | Method and system using mathematical analysis and machine learning related to a disease |
US11071501B2 (en) | 2015-08-14 | 2021-07-27 | Elucid Bioiwaging Inc. | Quantitative imaging for determining time to adverse event (TTE) |
US11094058B2 (en) | 2015-08-14 | 2021-08-17 | Elucid Bioimaging Inc. | Systems and method for computer-aided phenotyping (CAP) using radiologic images |
US10176408B2 (en) | 2015-08-14 | 2019-01-08 | Elucid Bioimaging Inc. | Systems and methods for analyzing pathologies utilizing quantitative imaging |
US11087459B2 (en) | 2015-08-14 | 2021-08-10 | Elucid Bioimaging Inc. | Quantitative imaging for fractional flow reserve (FFR) |
US11113812B2 (en) | 2015-08-14 | 2021-09-07 | Elucid Bioimaging Inc. | Quantitative imaging for detecting vulnerable plaque |
US10517678B2 (en) * | 2015-10-02 | 2019-12-31 | Heartflow, Inc. | System and method for diagnosis and assessment of cardiovascular disease by comparing arterial supply capacity to end-organ demand |
WO2018050806A1 (en) * | 2016-09-16 | 2018-03-22 | Koninklijke Philips N.V. | Apparatus and method for determining a fractional flow reserve |
WO2018133118A1 (zh) * | 2017-01-23 | 2018-07-26 | 上海联影医疗科技有限公司 | 血流状态分析系统及方法 |
EP3573531B1 (en) | 2017-01-24 | 2021-07-28 | Spectrum Dynamics Medical Limited | Systems for computation of functional index parameter values for blood vessels |
EP3378398A1 (en) * | 2017-03-24 | 2018-09-26 | Koninklijke Philips N.V. | Myocardial ct perfusion image synthesis |
EP3644857A1 (en) * | 2017-06-30 | 2020-05-06 | Koninklijke Philips N.V. | Machine learning spectral ffr-ct |
US11589924B2 (en) * | 2017-08-01 | 2023-02-28 | Siemens Healthcare Gmbh | Non-invasive assessment and therapy guidance for coronary artery disease in diffuse and tandem lesions |
EP3489893B1 (en) * | 2017-11-22 | 2020-06-24 | Siemens Healthcare GmbH | Method and system for assessing a haemodynamic parameter |
US11133109B2 (en) * | 2017-12-29 | 2021-09-28 | Analytics For Life Inc. | Method and system to assess disease using phase space volumetric objects |
US11918333B2 (en) | 2017-12-29 | 2024-03-05 | Analytics For Life Inc. | Method and system to assess disease using phase space tomography and machine learning |
CN108717695B (zh) * | 2018-04-25 | 2021-07-13 | 数坤(北京)网络科技股份有限公司 | 心脏冠脉血管自动分段命名方法 |
US11471090B2 (en) | 2018-06-04 | 2022-10-18 | Analytics For Life Inc. | Method and system to assess pulmonary hypertension using phase space tomography and machine learning |
CN109190618B (zh) * | 2018-08-17 | 2021-06-25 | 重庆大学 | 基于图像识别技术的高温熔渣流量测量装置及方法 |
JP7246907B2 (ja) * | 2018-12-12 | 2023-03-28 | 日本メジフィジックス株式会社 | 心筋核医学画像データのスコアリング |
CN109717953B (zh) * | 2019-02-01 | 2021-01-08 | 杭州晟视科技有限公司 | 一种血流量的确定方法、装置、电子设备和计算机存储介质 |
US10861157B2 (en) | 2019-04-04 | 2020-12-08 | Medtronic Vascular, Inc. | System and methods for determining modified fractional flow reserve values |
CN112950544A (zh) * | 2021-02-02 | 2021-06-11 | 深圳睿心智能医疗科技有限公司 | 一种确定冠脉参数的方法 |
CN113100737B (zh) * | 2021-04-06 | 2023-10-27 | 复旦大学附属中山医院 | 基于冠状动脉cta的缺血心肌负荷定量评价系统 |
EP4349262A1 (en) * | 2022-10-06 | 2024-04-10 | Koninklijke Philips N.V. | Flow state normalization for functional cta |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5431161A (en) | 1993-04-15 | 1995-07-11 | Adac Laboratories | Method and apparatus for information acquistion, processing, and display within a medical camera system |
GB0221434D0 (en) | 2002-09-16 | 2002-10-23 | Houston John G | A method of analysing fluid flow in a conduit |
IL165636A0 (en) | 2004-12-08 | 2006-01-15 | Paieon Inc | Method and apparatus for finding the coronary velocity and flow and related parameters |
EP1830701A1 (en) | 2004-12-08 | 2007-09-12 | Paieon Inc. | Method and apparatus for blood vessel parameter determinations |
CN101495039B (zh) | 2005-09-22 | 2012-05-30 | 皇家飞利浦电子股份有限公司 | 用于能谱ct的定量物质分解 |
WO2007110795A2 (en) | 2006-03-29 | 2007-10-04 | Philips Intellectual Property & Standards Gmbh | Effective dual-energy x-ray attenuation measurement |
DE102007029886B4 (de) * | 2007-06-28 | 2016-10-06 | Siemens Healthcare Gmbh | Verfahren zum Segmentieren einer Herzmuskelwand und Vorrichtung zur Detektion einer pathologisch veränderten Koronararterie |
WO2009077978A1 (en) | 2007-12-19 | 2009-06-25 | Philips Intellectual Property & Standards Gmbh | Method for acquiring 3-dimensional images of a myocardium, particularly of a myocardial blush |
DE102008014792B3 (de) | 2008-03-18 | 2009-06-18 | Siemens Aktiengesellschaft | Verfahren und Vorrichtung zur Simulation eines Blutflusses in einem Gefäßabschnitt |
US8200466B2 (en) | 2008-07-21 | 2012-06-12 | The Board Of Trustees Of The Leland Stanford Junior University | Method for tuning patient-specific cardiovascular simulations |
EP2350889A2 (en) | 2008-08-25 | 2011-08-03 | ETH Zurich | Method and system for obtaining high-resolution flow-field data from sparse measurement data |
US20100130878A1 (en) | 2008-11-24 | 2010-05-27 | General Electric Company | Systems, apparatus and processes for automated blood flow assessment of vasculature |
US9405886B2 (en) | 2009-03-17 | 2016-08-02 | The Board Of Trustees Of The Leland Stanford Junior University | Method for determining cardiovascular information |
CN102232857A (zh) * | 2010-05-06 | 2011-11-09 | 高春平 | 非创伤性聚焦超声冠状动脉体外溶栓系统 |
CN102232856A (zh) * | 2010-05-06 | 2011-11-09 | 高春平 | 双频超声多维聚焦脑血管溶栓系统 |
US20110307231A1 (en) | 2010-06-09 | 2011-12-15 | Jens Kirchner | Method and arrangement for creating an individualized, computer-aided model of a system, and a corresponding computer program and a corresponding machine-readable storage medium |
US8682626B2 (en) | 2010-07-21 | 2014-03-25 | Siemens Aktiengesellschaft | Method and system for comprehensive patient-specific modeling of the heart |
CN101889861B (zh) * | 2010-07-28 | 2011-10-26 | 沈阳恒德医疗器械研发有限公司 | 心脑血管特性与血流特性分析仪 |
US8315812B2 (en) | 2010-08-12 | 2012-11-20 | Heartflow, Inc. | Method and system for patient-specific modeling of blood flow |
US8157742B2 (en) | 2010-08-12 | 2012-04-17 | Heartflow, Inc. | Method and system for patient-specific modeling of blood flow |
US9119540B2 (en) | 2010-09-16 | 2015-09-01 | Siemens Aktiengesellschaft | Method and system for non-invasive assessment of coronary artery disease |
DE102010043849B3 (de) * | 2010-11-12 | 2012-02-16 | Siemens Aktiengesellschaft | Vorrichtung und Computertomograph zur Bestimmung und Darstellung der Durchblutung des Herzmuskels |
US10186056B2 (en) | 2011-03-21 | 2019-01-22 | General Electric Company | System and method for estimating vascular flow using CT imaging |
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2013
- 2013-11-21 EP EP13824654.1A patent/EP2932469B1/en active Active
- 2013-11-21 RU RU2015128005A patent/RU2015128005A/ru not_active Application Discontinuation
- 2013-11-21 CN CN201380064745.8A patent/CN104871211B/zh active Active
- 2013-11-21 BR BR112015013248A patent/BR112015013248A2/pt not_active IP Right Cessation
- 2013-11-21 JP JP2015547208A patent/JP5953438B2/ja active Active
- 2013-11-21 WO PCT/IB2013/060294 patent/WO2014091339A1/en active Application Filing
- 2013-11-21 US US14/647,860 patent/US9867584B2/en active Active
Also Published As
Publication number | Publication date |
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EP2932469A1 (en) | 2015-10-21 |
CN104871211A (zh) | 2015-08-26 |
RU2015128005A (ru) | 2017-01-19 |
US20150297161A1 (en) | 2015-10-22 |
US9867584B2 (en) | 2018-01-16 |
JP2016504084A (ja) | 2016-02-12 |
JP5953438B2 (ja) | 2016-07-20 |
EP2932469B1 (en) | 2018-10-31 |
CN104871211B (zh) | 2018-09-11 |
WO2014091339A1 (en) | 2014-06-19 |
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